Obstet Gynecol Sci.  2014 Nov;57(6):534-538. 10.5468/ogs.2014.57.6.534.

Recurrent ovarian steroid cell tumor, not otherwise specified managed with debulking surgery, radiofrequency ablation, and adjuvant chemotherapy

  • 1Department of Obstetrics and Gynecology, Wonkwang University School of Medicine, Iksan, Korea. caduceus4u@naver.com


Steroid cell tumors, not otherwise specified, are infrequently encountered ovarian neoplasms, which constitute <0.1% of all ovarian tumors. Most of these tumors are unilateral, and almost one-third of all cases are reportedly malignant. However, because most of these tumors are diagnosed in the early stage, and do not recur or metastasize, little is known about their response to therapies such as chemotherapy or radiation. Here, we present a rare case of recurrent steroid cell tumor, not otherwise specified that showed a complete response after debulking surgery, radiofrequency ablation, and adjuvant chemotherapy.


Adjuvant chemotherapy; Debulking surgery; Radiofrequency ablation; Recurrent steroid cell tumor

MeSH Terms

Catheter Ablation*
Chemotherapy, Adjuvant*
Drug Therapy
Ovarian Neoplasms


  • Fig. 1 (A) Preoperative abdominopelvic computed tomography shows 24-mm arterial well-enhancing mass at segment 5 of liver and 30-mm well-enhancing omental mass at paracolic gutter space. (B,C) Abdominopelvic computed tomography and positron emission tomography/computed tomography after the completion of treatment shows no definitive noticeable nodules and discrete fluorodeoxyglucose uptake noted at the peritoneal cavity and liver.

  • Fig. 2 (A) Steroid cell tumor, not otherwise specified composed of cells with abundant eosinophilic to clear cytoplasm. The cells have an appearance similar to adrenal cortical cells (H&E, ×200). (B) Diffuse nuclear and cytoplasmic staining for inhibin-a in steroid cell tumor (×200). (C) Diffuse nuclear and cytoplasmic staining for calretinin in steroid cell tumor (×200).


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