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Coexistence of Cerebral Microbleeds and Amyloid Pathology in Patients with Cognitive Complaints

Lim EY, Ryu SY, Shim YS, Yang DW, Cho AH

BACKGROUND AND PURPOSE: We investigated the prevalence of amyloid positivity and cerebral microbleeds (CMBs) in subjects with cognitive complaints with the aim of identifying differences in clinical parameters and cognitive...
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Relationships between [¹⁸F]-THK5351 Retention and Language Functions in Primary Progressive Aphasia

Jeong HJ, Yoon CW, Seo S, Lee SY, Suh MK, Seo HE, Kim WR, Lee H, Heo JH, Lee YB, Park KH, Choi SH, Ido T, Lee KM, Noh Y

BACKGROUND AND PURPOSE: There are three distinct subtypes of primary progressive aphasia (PPA): the nonfluent/agrammatic variant (nfvPPA), the semantic variant (svPPA), and the logopenic variant (lvPPA). We sought to characterize...
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Cerebral Amyloid Quantification in Cognitively Normal Korean Adults Using F-18 Florbetaben PET

Jeong J, Jeong YJ, Park KW, Kang DY

PURPOSE: To investigate regional cerebral amyloid beta retention in cognitively normal Korean adults using F-18 florbetaben (FBB). METHODS: We prospectively analyzed F-18 FBB positron emission tomography (PET)/CT scans of 30 cognitively...
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The Effect of Daily Low Dose Tadalafil on Cerebral Perfusion and Cognition in Patients with Erectile Dysfunction and Mild Cognitive Impairment

Choi JB, Cho KJ, Kim JC, Kim CH, Chung YA, Jeong HS, Shim YS, Koh JS

OBJECTIVE: The aims of this study were to investigate the effects of daily low-dose tadalafil on cognitive function and to examine whether there was a change in cerebral blood flow...
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A Comprasion of the Activation of Mirror Neurons Induced by Action Observation between Simple and Complex Hand Movement

Lee MY, Kim JS

PURPOSE: We compared the activation pattern of the mirror neurons (MN) between two types of hand movement according to action observation using functional MRI. METHODS: Twelve right-handed healthy subjects (5 male...
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Pilot Study: An Ocular Biomarker for Diagnosis of Attention Deficit Hyperactivity Disorder

Bae S, Kim JT, Han JM, Han DH

OBJECTIVE: Biomarkers of attention deficit hyperactivity disorder (ADHD) are crucial for early diagnosis and intervention, in which the identification of biomarkers in other areas of the body that represent the...
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Effects of Amisulpride Adjunctive Therapy on Working Memory and Brain Metabolism in the Frontal Cortex of Patients with Schizophrenia: A Preliminary Positron Emission Tomography/Computerized Tomography Investigation

Park JH, Hong JS, Kim SM, Min KJ, Chung US, Han DH

OBJECTIVE: Dopamine plays a significant role in working memory by acting as a key neuromodulator between brain networks. Additionally, treatment of patients with schizophrenia using amisulpride, a pure dopamine class...
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A Functional Domain Based Approach in Neurocognitive Rehabilitation with Transcranial Direct Current Stimulation: A Case Report

Sreeraj VS, Shivakumar V, Bose A, Abhiram PN, Agarwal SM, Chhabra H, Narayanaswamy JC, Venkatasubramanian G

Transcranial direct current stimulation (tDCS) is a novel brain stimulation technique which has kindled hope in alleviating motor, language as well as cognitive deficits in neuronal injury. Current case report...
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Fear Network Model in Panic Disorder: The Past and the Future

Lai CH

The core concept for pathophysiology in panic disorder (PD) is the fear network model (FNM). The alterations in FNM might be linked with disturbances in the autonomic nervous system (ANS),...
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Postpartum Superior Sagittal Sinus Thrombosis: A Case Report

Han KH, Won YD, Na MK, Han MH, Ryu JI, Kim JM, Kim CH, Cheong JH

Cerebral venous sinus thrombosis (CVST) is a rare disease. Early diagnosis and treatment are important, as CVST is potentially fatal. Pregnancy and puerperium are known risk factors for CVST. Here,...
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Pheochromocytoma with Brain Metastasis: A Extremely Rare Case in Worldwide

Cho YS, Ryu HJ, Kim SH, Kang SG

Pheochromocytoma (PCC) is a neuroendocrine tumor that mainly arises from the medulla of the adrenal gland. Some PCCs become malignant and metastasize to other organs. For example, it typically involves...
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Metaplastic Meningioma Overspreading the Cerebral Convexity

Choi YH, Choi CY, Lee CH, Koo HW, Chang SH

Meningioma is relatively common, benign, and extra-axial tumor accounting for about 20% of primary brain and spinal cord tumors. The World Health Organization (WHO) classified these tumors into Grade I...
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FDG PET Findings according to Wandering Patterns of Patients with Drug-naïve Alzheimer's Disease

Yang Y, Kwak YT

BACKGROUND AND PURPOSE: To explore anatomic substrate of specific wandering patterns in patients with Alzheimer's disease (AD) by performing positron emission tomography with 18F fluorodeoxyglucose positron emission tomography (FDG PET). METHODS:...
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Brain Regional Homogeneity Changes in Cirrhotic Patients with or without Hepatic Encephalopathy Revealed by Multi-Frequency Bands Analysis Based on Resting-State Functional MRI

Zhang G, Cheng Y, Shen W, Liu B, Huang L, Xie S

OBJECTIVE: To investigate brain regional homogeneity (ReHo) changes of multiple sub-frequency bands in cirrhotic patients with or without hepatic encephalopathy using resting-state functional MRI. MATERIALS AND METHODS: This study recruited 46...
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Use of the facial dismasking flap approach for surgical treatment of a multifocal craniofacial abscess

Ishii Y, Yano T, Ito O

The decision of which surgical approach to use for the treatment of a multifocal craniofacial abscess is still a controversial matter. A failure to control disease progress in the craniofacial...
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Regional Brain Activity During Rest and Gastric Water Load in Subtypes of Functional Dyspepsia: A Preliminary Brain Functional Magnetic Resonance Imaging Study

Chen Y, Wang R, Hou B, Feng F, Fang X, Zhu L, Sun X, Wang Z, Ke M

  • KMID: 2413103
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):268-279.
  • doi: 10.5056/jnm17076
BACKGROUND/AIMS: Functional dyspepsia (FD) remains a great clinical challenge since the FD subtypes, defined by Rome III classification, still have heterogeneous pathogenesis. Previous studies have shown notable differences in visceral...
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Hydrocephalus in a Patient with Alzheimer's Disease

Kang MJ, Park YH, Kim S, Yi S

BACKGROUND: Normal pressure hydrocephalus (NPH) is an etiology of dementia that is reversible following cerebrospinal fluid shunt placement, however, surgical intervention not always clinically effective and the respons to shunt...
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Obesity and Brain Positron Emission Tomography

Pak K, Kim SJ, Kim IJ

Obesity, an increasingly common problem in modern societies, results from energy intake chronically exceeding energy expenditure. This imbalance of energy can be triggered by the internal state of the caloric...
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Changes in Regional Cerebral Perfusion after Nicergoline Treatment in Early Alzheimer's Disease: A Pilot Study

Im JJ, Jeong HS, Park JS, Yang Y, Na SH, Oh JK, Chung YA, Song IU

BACKGROUND AND PURPOSE: Nicergoline is an ergoline derivative that is used to treat cognitive deficits in cerebrovascular disease and various forms of dementia. Although therapeutic effects of nicergoline have been...
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Neural Correlates of Motor Recovery Measured by SPECT at Six Months After Basal Ganglia Stroke

Choi JW, Kim MH, Park SA, Sin DS, Kim MS

OBJECTIVE: To investigate neural correlates associated with recovery of motor function over 6 months in patients with basal ganglia (BG) stroke using acetazolamide (ACZ) stress brain-perfusion single-photon emission computed tomography...
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