J Korean Assoc Oral Maxillofac Surg.
2003 Feb;29(1):1-4.
Differentiation of adult canine bone marrow stem cells into neurons
- Affiliations
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- 1Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea. choibh@wonju.yonsei.ac.kr
- 2Department of Dentistry, Kangnung Asan Hospital, Korea.
- 3Department of Otolaryngology, Wonju College of Medicine, Yonsei University, Korea.
- 4Me-Plus dental clinic, Korea.
- 5Korean Baylor Academy and KIDA, Korea.
Abstract
- In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with DMSO/BHA/FeCl2. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by FeCl2. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.
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