Clin Exp Reprod Med.
2018 Dec;45(4):149-153. 10.5653/cerm.2018.45.4.149.
Bone marrow-derived stem cells contribute to regeneration of the endometrium
- Affiliations
-
- 1Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea. kwyi@korea.ac.kr
- KMID: 2427409
- DOI: http://doi.org/10.5653/cerm.2018.45.4.149
Abstract
- Stem cells are undifferentiated cells capable of self-renewal and differentiation into various cell lineages. Stem cells are responsible for the development of organs and regeneration of damaged tissues. The highly regenerative nature of the human endometrium during reproductive age suggests that stem cells play a critical role in endometrial physiology. Bone marrow-derived cells migrate to the uterus and participate in the healing and restoration of functionally or structurally damaged endometrium. This review summarizes recent research into the potential therapeutic effects of bone marrow-derived stem cells in conditions involving endometrial impairment.
