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From papyrus leaves to bioprinting and virtual reality: history and innovation in anatomy

Bisht B, Hope A, Paul MK

The human quest to master the anatomy and physiology of living systems started as early as 1600 BC, with documents from the Greeks, Indians, and Romans presenting the earliest systematic...
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Refeeding Syndrome as a Possible Cause of Very Early Mortality in Acute Pancreatitis

Jeon TJ, Lee KJ, Woo HS, Kim EJ, Kim YS, Park JY, Cho JH

BACKGROUND/AIMS: Refeeding syndrome (RFS) is a fatal clinical complication that can occur as a result of fluid and electrolyte shifts during early nutritional rehabilitation for malnourished patients. This study was...
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Bile Acid Transporters Are Expressed and Heterogeneously Distributed in Rat Bile Ducts

Luo ZL, Cheng L, Wang T, Tang LJ, Tian FZ, Xiang K, Cui L

BACKGROUND/AIMS: Cholangiocytes are capable of reabsorbing bile salts from bile, but the pathophysiological significance of this process is unclear. To this end, we detected the expression and distribution of bile...
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Neuroimmune interactions and kidney disease

Hasegawa S, Inoue T, Inagi R

The autonomic nervous system plays critical roles in maintaining homeostasis in humans, directly regulating inflammation by altering the activity of the immune system. The cholinergic anti-inflammatory pathway is a well-studied...
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Clinical and pharmacological application of multiscale multiphysics heart simulator, UT-Heart

Okada JI, Washio T, Sugiura S, Hisada T

A heart simulator, UT-Heart, is a finite element model of the human heart that can reproduce all the fundamental activities of the working heart, including propagation of excitation, contraction, and...
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Clinical Pearls of Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock

Choi MS, Sung K, Cho YH

Extracorporeal membrane oxygenation (ECMO) is a technique that uses a pump to drain blood from a body, circulate blood through a membrane lung, and return the oxygenated blood back into...
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Constrictive Pericarditis: A Medical or Surgical Disease?

Chang SA, Oh JK

Constrictive pericarditis is a disease of the pericardium resulting from chronic inflammation and/or scar responsible for a clinical feature of left and right ventricular failure. Although constrictive pericarditis has long...
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Artemisinin and the Nobel Prize in physiology or medicine 2015

Park JY

No abstract available.
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Sexual Knowledge, Sexual Attitudes, and Perceptions and Actualities of Sex Education among Elementary School Parents

Shin H, Lee JM, Min JY

PURPOSE: This study was conducted to understand sexual knowledge, sexual attitudes, and the perceptions and actualities of sex education among parents of elementary school children. METHODS: This is a descriptive study...
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Extracellular vesicles in renal physiology and clinical applications for renal disease

Kwon SH

Many cells in the nephron release extracellular vesicles (EVs). EVs envelop nucleic acids, proteins, and lipids. The surfaces of EVs express donor cell-specific markers, ligands, and major histocompatibility complex molecules....
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A Study on Clinical Variables Contributing to Differentiation of Delirium and Non-Delirium Patients in the ICU

Ko C, Kim JJ, Cho D, Oh J, Park JY

OBJECTIVES: It is not clear which clinical variables are most closely associated with delirium in the Intensive Care Unit (ICU). By comparing clinical data of ICU delirium and non-delirium patients,...
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Usefulness of the neutrophil-to-lmphocyte ratio as a prognostic predictor in elderly patients admitted to the intensive care unit through emergency department

Kim SK, Park JH, Oh S, Park SH, Kim HJ, Kim SH, Kim SW, Zhu J, Choi SP, Oh JH

OBJECTIVE: The purpose of this study was to test the hypothesis that an increase in the neutrophil-to-lymphocyte ratio (NLR) increases the risk of in-hospital density in patients aged 65 and...
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The problem of medicating women like the men: conceptual discussion of menstrual cycle-dependent psychopharmacology

Yum SK, Yum SY, Kim T

While hormonal changes during the ovulatory cycles affect multiple body systems, medical management, including medication dosing remains largely uniform between the sexes. Little is known about sex-specific pharmacology in women....
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Current Progress in Tendon and Ligament Tissue Engineering

Lim WL, Liau LL, Ng MH, Chowdhury , Law JX

BACKGROUND: Tendon and ligament injuries accounted for 30% of all musculoskeletal consultations with 4 million new incidences worldwide each year and thus imposed a significant burden to the society and...
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A physiology based model of heart rate variability

von Rosenberg W, Hoting MO, Mandic DP

Heart rate variability (HRV) is governed by the autonomic nervous system (ANS) and is routinely used to estimate the state of body and mind. At the same time, recorded HRV...
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Position Statement: Exercise Guidelines to Increase Peak Bone Mass in Adolescents

Min SK, Oh T, Kim SH, Cho J, Chung HY, Park DH, Kim CS

BACKGROUND: An increase in bone mineral density during adolescence increases resistance to fractures in older age. The Korean Society for Bone and Mineral Research and the Korean Society of Exercise...
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Outcomes of Modified Canal Wall Down Mastoidectomy and Mastoid Obliteration Using Autologous Materials

Kim BG, Kim HJ, Lee SJ, Lee E, Lee SA, Lee JD

OBJECTIVES: The traditional canal wall down mastoidectomy (CWDM) procedure commonly has potential problems of altering the anatomy and physiology of the middle ear and mastoid. This study evaluated outcomes in...
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Glimpse of Relation between Imaging and Physiology

Heo JH

No abstract available.
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Pleuropericardial Cyst Mimicking a Metastasis of Differentiated Thyroid Carcinoma on Whole-Body Iodine-131 Scan: a Case Report

Bourogianni O, Pagonidis , Stathaki M, Tsaroucha , Papadaki E, Koukouraki S

Post-therapeutic whole-body scan (WBS) with I-131 has been widely used for the follow-up of patients with well-differentiated thyroid cancer (DTC). Although the sensitivity of WBS with I-131 in detection of...
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Changes in Gastrointestinal Physiology in Obese Patients

Yun SH, Park JK, Shin JE, Diet, Obesity, and Metabolism Research Group of Korean Society of Neurogastroenterology and Motility

Obesity is a prevalent disease with significant morbidity and mortality. It is a state of chronic low-grade inflammation due to excess body fat. Weight homeostasis is maintained through changes in...
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