Clin Exp Reprod Med.
2014 Jun;41(2):80-85. 10.5653/cerm.2014.41.2.80.
Vitamin D deficiency in women with polycystic ovary syndrome
- Affiliations
-
- 1Department of Obstetrics and Gynecology, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea.
- 2The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea. ymchoi@snu.ac.kr
- 3Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
- 4Department of Obstetrics and Gynecology, Maria Fertility Hospital, Seoul, Korea.
- 5Department of Obstetrics and Gynecology, Seoul Municipal Boramae Hospital, Seoul, Korea.
- 6Department of Obstetrics and Gynecology, Graduate School of Medicine, Dongguk University, Seoul, Korea.
- KMID: 2049069
- DOI: http://doi.org/10.5653/cerm.2014.41.2.80
Abstract
OBJECTIVE
To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group.
METHODS
We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng/mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls.
RESULTS
Women with PCOS showed no differences in the level of 25-hydroxy vitamin D (19.6+/-6.6 ng/mL in patients vs. 20.1+/-7.4 ng/mL in controls, respectively, p=0.696) or prevalence of vitamin D deficiency (57.9% in patients vs. 56.5% in controls, respectively, p=0.880). In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls.
CONCLUSION
Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Studies on Fibrinolytic System Behavior in Women with Polycystic Ovary Syndrome
- Medical diagnosis and treatment of polycystic ovary syndrome
- Inter-ovarian differences in ultrasound markers of ovarian size in women with polycystic ovary syndrome
- Polycystic Ovary Syndrome and Women Health
- Epidemiology and Diagnostic Criteria of Polycystic Ovary Syndrome
