Korean J Anesthesiol.  2001 Sep;41(3):284-288. 10.4097/kjae.2001.41.3.284.

Effect of Midazolam, Fentanyl and Propofol for Intravenous Anesthesia in Patients Undergoing the Cardioversion

Affiliations
  • 1Department of Anesthesiology, College of Medicine, Catholic University, Seoul, Korea.
  • 2Department of Cardiology Division, College of Medicine, Catholic University, Seoul, Korea.
  • 3Department of Internal Medicine, College of Medicine, Catholic University, Seoul, Korea.

Abstract

BACKGROUND
Elective cardioversion is a short procedure performed under amnesia, sedation or anesthesia for the treatment of cardiac dysrhythmia. Midazolam, fentanyl and propofol on hemodynamic changes and side effects were studied.
METHODS
Thirty patients scheduled for an elective cardioversion in the coronary care unit received propofol 500microgram/kg I.V., followed by a continuous infusion with 25 75microgram/kg/min until they lost consciousness as determined by cessation of response to verbal command. All patients received midazolam 0.02 mg/kg and fentanyl 2microgram/kg I.V. 5 minutes before induction. In addition, the cardiologist administrated the electric shock. Blood pressures and heart rates were measured prior to induction, after the administration of midazolam and fentanyl, after cardioversion, 5 minutes after cardioversion and recovery. The recovery time from terminating drug administration to awakening, and the total dose of propofol were recorded. Patients were observed for side effects.
RESULTS
Systolic, mean, and diastolic blood pressures were significantly decreased 5 minutes after cardioversion and recovery. Heart rates were significantly decreased after cardioversion, 5 minutes after cardioversion and recovery. Recovery times were 22.1 14.9 minutes and the total dose of propofol was 0.79 0.39 mg/kg. Incidence of apnea (> 30 s) was 30%.
CONCLUSIONS
We concluded that midazolam, fentanyl and propofol in patients undergoing an electric cardioversion decreased blood pressure and heart rate, but the cardiovascular status was maintained within clinically acceptable levels.

Keyword

Anesthetics; fentanyl; midazolam; propofol; cardioversion; hemodynamics

MeSH Terms

Amnesia
Anesthesia
Anesthesia, Intravenous*
Anesthetics
Apnea
Arrhythmias, Cardiac
Blood Pressure
Consciousness
Coronary Care Units
Electric Countershock*
Fentanyl*
Heart Rate
Hemodynamics
Humans
Incidence
Midazolam*
Propofol*
Shock
Anesthetics
Fentanyl
Midazolam
Propofol
Full Text Links
  • KJAE
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr