J Korean Geriatr Soc.
2010 Sep;14(3):171-174. 10.4235/jkgs.2010.14.3.171.
A Case of Dopamine Dysregulation Syndrome and Repetitive Behavior Caused by Levodopa in Parkinson's Disease
- Affiliations
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- 1Department of Neurology, Kosin University College of Medicine, Busan, Korea. merritt329@hanmail.net
- KMID: 2015199
- DOI: http://doi.org/10.4235/jkgs.2010.14.3.171
Abstract
- Levodopa treatment in Parkinson's disease (PD) can cause a wide range of non-motor manifestations including poor impulse control and stereotyped behaviors. Punding is a term used to describe complex prolonged, purposeless and repetitive behavior in patients under dopamine replacement therapy. We report a 64-year-old PD patient who, concomitantly with self-increment of levodopa, developed punding behaviors in association with dopamine dysregulation syndrome. Gradual reduction of dopaminergic medication partially alleviated repetitive behavior over time.
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