Korean J Geriatr Gerontol.  2013 Dec;14(2):66-70.

Impulse Control and Repetitive Behavior Disorders in Parkinson’s Disease

• Kim SJ
• Yoo BG

Abstract

Background
Parkinson's disease (PD) is an increasing chronic neurodegenerative disease. Motor symptoms are the main criteria in diagnosing PD. However PD patients are suffered from non motor symptoms as much as motor symptoms. Among non motor symptoms impulse control and repetitive behavior disorders (ICRBs) deprives the patient's quality of life, so treatment for ICRBs has become important. The purpose of this study is to determine how many patients are affected on ICRBs and which factors affect the development of ICRBs.
Methods
The study was done among 206 Parkinson's disease patients enrolled in Pusan Paik Hospital Parkinson's disease center. The questionnaire for impulsive-compulsive disorders in Parkinson's disease (QUIP) was used in evaluating ICRBs. Frequency analysis was used to find the prevalence rates of ICRBs among PD patients. Univariate analysis were used to analyze which factors affect ICRBs.
Results
33 patients (16%) had ICRBs. Hobbyism, eating, buying, punding were relatively common while sexual behaviors, gambling and walkabout occurred less frequently. On Univariate analysis, factors significantly associated with ICRBs were age, dopamine agonist use, levodopa daily dose (LDD), total levodopa equivalent daily dose.
Conclusion
Our findings suggest that the ICRBs are associated with age, dopamine agonist use, LDD, total LEDD in PD patients. The dopamine agonists and increase of levodopa doses should be carefully prescribed in PD patients with high risk of ICRBs.

Keyword

Parkinson’s disease; Impulse control disorder