Korean J Nephrol.  1999 Jul;18(4):625-629.

A Case of Acute Interstitial Nephritis and Myoglobinuria after Alcohol Drinking

Affiliations
  • 1Department of Internal Medicine, Korea Veterans Hospital, Seoul, Korea.
  • 2Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea.

Abstract

Rhabdomyolysis is defined as skeletal muscle injury with release of muscle cell constituents into the plasma and may lead to acute renal failure secondary to myoglobinuria. The causes of rhabdomyolysis is diverse:alcohol abuse, primary muscle disease, disturbance of muscle metabolism, sustained seizure, infection, drugs, tox ins, trauma, severe exercise, CO intoxication etc. Rhabdomyolysis may cause acute derangement in electrolyte balance and death. It should be diagnosed earlier and managed properly. We experienced a 49 year-old woman developed acute renal failure and myoglobinuria after alcohol drinking. A kidney biopsy revealed acute interstitial nephritis. In the presence of otherwise unexplained acute renal failure in alcoholic patients, rhabdomyolysis should be considered in the differential diagnosis.

Keyword

Rhabdomyolysis; Myogobinuria; Acute renal failure; Acute interstitial nephritis; Alcohol

MeSH Terms

Acute Kidney Injury
Alcohol Drinking*
Alcoholics
Biopsy
Diagnosis, Differential
Female
Humans
Kidney
Metabolism
Middle Aged
Muscle Cells
Muscle, Skeletal
Myoglobinuria*
Nephritis, Interstitial*
Plasma
Rhabdomyolysis
Seizures
Water-Electrolyte Balance
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