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Impact of Sarcopenia on the Risk of Erosive Esophagitis

Heo CM, Kim TJ, Lee H, Pyo JH, Min YW, Min BH, Lee JH, Son HJ, Baek SY, Kim K, Ryu S, Rhee PL, Kim JJ

BACKGROUND/AIMS: An association between obesity and erosive esophagitis has been reported, but the effects of sarcopenia and obesity on erosive esophagitis are unknown. This study examined the relationship between obesity,...
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Impact of Skeletal Muscle Mass on Metabolic Health

Kim G, Kim JH

Skeletal muscle is regarded as an endocrine and paracrine organ. Muscle-derived secretory proteins, referred to as myokines, mediate interactions between skeletal muscle mass and other organs such as the liver,...
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Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women

Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB

BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown....
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Prognostic Value of Skeletal Muscle Depletion Measured on Computed Tomography for Overall Survival in Patients with Non-Metastatic Breast Cancer

Huh J, Park B, Lee H, An YS, Jung Y, Kim JY, Kang DK, Kim KW, Kim TH

PURPOSE: The purpose of this study was to evaluate the prognostic value of skeletal muscle depletion measured on computed tomography (CT) in patients with non-metastatic invasive breast cancer. METHODS: This retrospective...
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Assessment of neovascularization during bone healing using contrast-enhanced ultrasonography in a canine tibial osteotomy model: a preliminary study

Jeon S, Jang J, Lee G, Park S, Lee SK, Kim H, Choi J

Blood perfusion of skeletal muscle and callus was evaluated using contrast-enhanced ultrasonography (CEUS) in a canine osteotomy model to determine the applicability of CEUS in the assessment of neovascularization during...
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Development and Validation of a Deep Learning System for Segmentation of Abdominal Muscle and Fat on Computed Tomography

Park HJ, Shin Y, Park J, Kim H, Lee IS, Seo DW, Huh J, Lee TY, Park T, Lee J, Kim KW

OBJECTIVE: We aimed to develop and validate a deep learning system for fully automated segmentation of abdominal muscle and fat areas on computed tomography (CT) images. MATERIALS AND METHODS: A fully...
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Relationships between Spinal Sarcopenia and Spinal Sagittal Balance in Older Women

Kim DH, Lee SY, Park SJ, Lee YS

BACKGROUND: Spinal sarcopenia is receiving renewed attention as a cause of spinal sagittal imbalance. However, the relationships between spinal sarcopenia and spinal sagittal balance (SSB) have not been thoroughly investigated....
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Exercise, the Gut Microbiome, and Frailty

Shin HE, Kwak SE, Lee JH, Zhang D, Bae JH, Song W

The gut microbiome is deeply associated with both skeletal muscle and brain function. In particular, gut microbiome dysbiosis may accelerate age-related diseases by affecting these systems. Although there is increasing...
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Pharmacological Interventions for Treatment of Sarcopenia: Current Status of Drug Development for Sarcopenia

Kwak JY, Kwon KS

Sarcopenia, the loss of skeletal muscle mass and function with age, was first recognized as a disease in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) (M62.84) and...
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Effectiveness of ultrasonographic skeletal muscle assessment in patients after total knee arthroplasty

Kitsuda Y, Tanimura C, Inoue K, Park D, Osaki M, Hagino H

OBJECTIVES: This study aimed to characterize the skeletal muscles of patients who underwent total knee arthroplasty (TKA) using ultrasonography in order to investigate the effectiveness of ultrasonographic skeletal muscle assessment...
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Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice

Zhang D, Lee JH, Kwak SE, Shin HE, Zhang Y, Moon HY, Shin DM, Seong JK, Tang L, Song W

BACKGROUND: Autophagy maintains metabolic homeostasis of muscles, and its impairment may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long-term high-fat diet. This study aimed to explore the...
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A Review of the Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Lean Body Mass in Humans

Sargeant J, Henson J, King JA, Yates T, Khunti K, Davies MJ

Weight loss is an important goal in the management of several chronic conditions, including type 2 diabetes mellitus, and pharmacological therapies that aid weight loss are appealing. Glucagon-like peptide-1 receptor...
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Architectural Changes in the Medial Gastrocnemius on Sonography after Nerve Ablation in Healthy Adults

Park JE, Seong YJ, Kim ES, Park D, Lee Y, Park H, Rha DW

Architectural changes in healthy muscle after denervation have not yet been reported. This study aimed to investigate architectural changes in the medial head of the gastrocnemius muscle (GCM) after aesthetic...
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Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model

Lee D, Seo Y, Kim YW, Kim S, Choi J, Moon SH, Bae H, Kim HS, Kim H, Kim JH, Kim TY, Kim E, Yim S, Lim I, Bang H, Kim JH, Ko JH

Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in...
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Paraneoplastic Dermatomyositis with Severe Itching

Oh JH, Park HJ, Choi M, Park HJ

  • KMID: 2457692
  • Korean J Dermatol.
  • 2019 Aug;57(7):395-398.
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by typical cutaneous manifestation and inflammation of the skeletal muscles. However, this progressive symmetric proximal muscle weakness may be minimal or absent...
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MBP-FGF2-Immobilized Matrix Maintains Self-Renewal and Myogenic Differentiation Potential of Skeletal Muscle Stem Cells

Sah JP, Hao NT, Kim Y, Eigler T, Tzahor E, Kim SH, Hwang Y, Yoon JK

The robust capacity of skeletal muscle stem cells (SkMSCs, or satellite cells) to regenerate into new muscles in vivo has offered promising therapeutic options for the treatment of degenerative muscle...
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The impact of sarcopenia on health-related quality of life in elderly people: Korean National Health and Nutrition Examination Survey

Sun DS, Lee H, Yim HW, Won HS, Ko YH

BACKGROUND/AIMS: The purpose of the study is to investigate the associations between sarcopenia and health-related quality of life in elderly men and women in Korea. METHODS: In a cross-sectional study using...
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Contrast Enhanced Ultrasound Perfusion Imaging in Skeletal Muscle

Nguyen T, Davidson B

The ability to accurately evaluate skeletal muscle microvascular blood flow has broad clinical applications for understanding the regulation of skeletal muscle perfusion in health and disease states. Contrast-enhanced ultrasound (CEU)...
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Sarcopenia Is Significantly Associated with Presence and Severity of Nonalcoholic Fatty Liver Disease

Chung GE, Kim MJ, Yim JY, Kim JS, Yoon JW

BACKGROUND: The association between nonalcoholic fatty liver disease (NAFLD) and sarcopenia has been suggested. We investigated the association between sarcopenia and NAFLD independent of visceral adiposity and searched for the...
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Fall Risk Assessment of Rural Elderly Population in Korea

Park D, Jo H, Yoon CH, Lee ES, Oh MK, Lee CH

OBJECTIVE: To investigate the risk factors for fall in the elderly population residing in rural areas of Korea and provide useful data for their prevention. METHODS: As part of farmers’ health...
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