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β-Patchoulene: Conversion from Patchouli Alcohol by Acid Catalysts and its In silico Anti-inflammatory Study

F, Soekamto NH, Firdausiah S, Rasyid H, Rifai A

β-patchoulene (β-PAE) is a tricyclic sesquiterpene which performed many potential bioactivities and can be found in patchouli oil but in very low concentration. This study aimed to obtained β-PAE in...
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University Freshmen's Problem Drinking: Its Individual- and Family-Level Factors

Moon J, Noh S, Youn Y, Kim Y, Kang E, Choo J

Background: University students have been known as having a higher rate of problem drinking than the general population in South Korea. In particular, the university freshmen may experience problem drinking...
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The association between alcohol use and suicide attempt in employees

Choo WY, Lee U, Park JH, Shin YC, Sim M, Oh KS, Shin DW, Jeon SW, Kim MK, Cho SJ

Purpose: This study aimed to analyze the alcohol use patterns that may influence suicide attempt in employees who have suicidal ideation. Methods: The 15,199 participants were classified into three groups according...
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Association Between Suicide Risk and Comorbidity of Mood Disorder and Alcohol Use Disorder: Using Common Data Model in Psychiatry

Cho YH, Lee E, Her ES, Hwang G, Lim KY, Noh JS, Shin Y, Hong CH, Roh HW, Lee D, Lee H, Kim D, Park RW, Park B, Son SJ

Objectives This study determines the effects of comorbidity of mood disorder and alcohol use disorder on suicide behavior. Methods We converted data from the electronic medical records of one university hospital...
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Choreiform Dyskinesia as a Sole Manifestation of Alcohol Withdrawal Syndrome

Yoon S, Do TH, Park JH

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Effect of Coffee, Tobacco, and Alcohol on Parkinson’s Disease

Seol W, Kim H, Son I

Since the neuroprotective effects of coffee and tobacco on Parkinson’s disease have been reported more than 50 years ago, clinical studies using caffeine and nicotine that were presumed as effective...
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Association between Alcohol Consumption and Serum Cortisol Levels: a Mendelian Randomization Study

Yang JH, Kweon SS, Lee YH, Choi SW, Ryu SY, Nam HS, Park KS, Kim HY, Shin MH

Background: Several studies have reported conflicting results regarding the relationship between alcohol consumption and cortisol levels. However, the causality between alcohol consumption and cortisol levels has not been evaluated. Methods: This...
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Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans

Choi CK, Shin MH, Cho SH, Kim HY, Zheng W, Long J, Kweon SS

Purpose Excessive alcohol consumption has been linked to an increased risk of colorectal cancer (CRC). We evaluated the association between alcohol-related genetic variants and CRC risk. Materials and Methods The study...
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Effectiveness of Drinking Reduction Program Focused on Self-Determination Enhancement for College Students with Problematic Drinking

Ma JK, Yoo MS

Purpose: This study examined the impact of a drinking reduction program on drinking motivation, drinking refusal self-efficacy, and problematic drinking behaviors in college students with problematic drinking habits. Methods: This...
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Causal effect of alcohol use on the risk of end-stage kidney disease and related comorbidities: a Mendelian randomization study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: An inverse observational association between alcohol use and the risk of chronic kidney disease (CKD) or end-stage kidney disease (ESKD) has been reported. The causal effect of alcohol use...
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Changing Trends in Liver Cirrhosis Etiology and Severity in Korea: the Increasing Impact of Alcohol

Yoon JH, Jun CH, Kim JH, Yoon EL, Kim BS, Song JE, Suk KT, Kim MY, Kang SH

Background: Chronic hepatitis B is the most common cause of liver cirrhosis in South Korea. However, alcoholic liver disease has shown an increasing trend. Although the clinical implications surrounding liver...
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A Study of Criminal Manifestation and Characteristics of Elderly Mental Illness

Cha S, Lim KO, Cho SN, Jang S, Han S

Objective: As the population of the elderly increases, the prevalence of dementia and other mental diseases of the elderly is also increasing. Dementia is a typical elderly mental illness. Some...
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From nonalcoholic fatty liver disease to metabolic-associated fatty liver disease: Big wave or ripple?

Kang SH, Cho Y, Jeong SW, Kim SU, Lee JW, On behalf of Korean NAFLD Study Group

There is some dissatisfaction with the term “nonalcoholic fatty liver disease (NAFLD),” which overemphasizes alcohol and underemphasizes the importance of metabolic risk factors in this disease. Recently, a consensus recommended...
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Transepithelial Laser versus Alcohol Assisted Photorefractive Keratectomy Safety and Efficacy: 1-Year Follow-up of a Contralateral Eye Study

Gharieb HM, Awad-Allah MAA, Ahmed AA, Othman IS

Purpose: To compare single-step transepithelial photorefractive keratectomy (TPRK) to conventional alcohol assisted epithelial removal then photorefractive keratectomy (AAPRK) regarding pain, epithelial healing, visual acuity, corneal haze measured subjectively and objectively,...
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Comeback of ketamine: resurfacing facts and dispelling myths

Kumar A, Kohli A

Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from phencyclidine. It has since been used as an anesthetic and analgesic. In addition, it has bronchodilating,...
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Factors Related to Problem Drinking and Solitary Drinking: Online Survey with One Person Household Women in Early Adulthood

Lim J, Kim H

Purpose: The purpose of this study was to investigate the factors related to the problem drinking in young adult women who lived and drank alone. Methods: This online survey (N=291)...
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The Interaction of Inflammatory Markers and Alcohol-Use on Cognitive Function in Korean Male Firefighters

Yun JA, Jeong KS, Ahn YS, Han Y, Choi KS

Objective Cognitive functions have been shown to become impaired due to alcoholism. Recently, neuroinflammation gained attention for playing a role in the neurotoxic effect of alcohol. However, there is limited...
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Ibuprofen Increases the Hepatotoxicity of Ethanol through Potentiating Oxidative Stress

Kim M, Lee EJ, Lim KM

Over 30 million prescriptions of NSAIDs (non-steroidal anti-inflammatory drugs) are issued every year. Considering that these drugs are available without a prescription as over the counter (OTC) drugs, their use...
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The Association between Alcohol Consumption and Grip Strength in a Nationwide Survey

Lee K

Background: Handgrip strength (HGS) is an important predictor of long-term health and physical function. Studies have associated alcohol consumption with HGS but based on inconsistent findings. The Korea National Health...
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Effects of Familial Alcohol Consumption on Alcohol Use Disorder, Depression, Anxiety, and Stress of University Students

Ryu KY, Park KW, Kim MS, Lee HJ, Paek sy, Park WJ, Oh MK

Background: Alcohol use disorder in early adulthood can be associated with psychological problems such as depression, anxiety, and stress. This study aimed to investigate the effect of familial alcohol consumption...
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