Korean J Med.
2006 Jan;70(1):101-106.
A case of Hashimoto's thyroiditis with chronic lymphocytic leukemia
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea. hjinkim@dankook.ac.kr
- 2Department of Diagnostic Radiology, College of Medicine, Dankook University, Cheonan, Korea.
- 3Department of Pathology, College of Medicine, Dankook University, Cheonan, Korea.
Abstract
- Hashimoto's thyroiditis is an autoimmune thyroid disease characterized by a gradual enlargement of the thyroid gland, extensive lymphocytic infiltration and fibrosis of thyroid follicles. Hashimoto's thyroiditis occurs frequently in conjunction with a wide range of organ-specific and systemic autoimmune diseases. The association of chronic lymphocytic leukemia with other autoimmune diseases also has been recognized. Here, we report a case of chronic lymphocytic leukemia diagnosed by abrupt painful swelling of the thyroid gland in a 69-year-old woman with Hashimoto's thyroiditis. The painful enlargement of goiter and elevated levels of antibodies to thyroglobulin were improved after chemotherapy with cyclophosphamide, vicristine and prednisolone.
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