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Pharmacological properties of the Thyrokitty injection (I-131) for the treatment of the feline hyperthyroidism

Lim JC, Kim DM, Nam SS, Cho EH, Lee SY, Chung HK, Lee I

Radioiodine (131I) has been used for the treatment of feline hyperthyroidism since the 1990s in the USA and Europe, and it is recommended as the most effective treatment for feline...
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Toxicological properties of the Thyrokitty injection (I-131) for the treatment of the feline hyperthyroidism

Lim JC, Kim DM, Nam SS, Cho EH, Lee SY, Chung HK, Lee I

Following the previous study, the toxicity of a single subcutaneous administration of the Thyrokitty injection (I-131) and the side effects that may occur at therapeutic doses were con-firmed. The Thyrokitty...
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Subclinical Hypothyroidism: Prevalence, Health Impact, and Treatment Landscape

Yoo WS, Chung HK

Subclinical hypothyroidism (sHypo) is defined as normal serum free thyroid hormone levels coexisting with elevated serum thyroid-stimulating hormone (TSH) levels. sHypo is a common condition observed in clinical practice with...
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A Case of an Elderly Graves’ Patient with Fatal Pulmonary Embolism

Lee JY, Yoo WS, Chung HK

In elderly Graves’ patients, thyrotoxicosis may have vague or atypical clinical features. It could delay the detection of Graves’ disease itself, and also other combined diseases. Here, we report a...
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The Management of Thyroid Disease in COVID-19 Pandemic

Yoo WS, Chung HK

The novel viral disease COVID-19 is spreading globally, causing countless infected individuals and deaths. There are active discussions and debates on how to manage patients with chronic illnesses in the...
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Analysis of the consumer perception and related education effect on the reduction of sugar for elementary school students in Seoul and Gyeonggi-do

Kim KN, Lee JS, Shim JS, Chung HK, Chung HR, Chang MJ

Purpose: This study examined the effects of nutritional education related to sugar in elementary school children on nutritional knowledge, attitude, and dietary behavior. Methods: A questionnaire survey on the knowledge, attitudes,...
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Modeling α-Synuclein Propagation with Preformed Fibril Injections

Chung HK, Ho HA, Pérez-Acuña D, Lee SJ

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Medical Treatment of Graves' Disease

Chung HK

Among the three treatment modalities of Graves' disease which include antithyroid drug (ATD), radioactive iodine and surgery, the ATD is most commonly preferred in Korea due to ease of use...
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Modeling α-Synuclein Propagation with Preformed Fibril Injections

Chung HK, Ho HA, Pérez-Acuña D, Lee SJ

The aggregation of α-synuclein (α-syn) has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Postmortem...
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Therapeutic Effect of Quadruple Oral Hypoglycemic Agents in Patients with Type 2 Diabetes Mellitus Who Have Insulin Limitations

Yoo WS, Kim DH, Kim HJ, Chung HK

BACKGROUND: Insulin therapy is the treatment of choice in type 2 diabetes mellitus (T2DM) patients who are not achieving glycemic goals despite triple oral hypoglycemic agent (OHA) combination therapy. However,...
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Socioeconomic burden of sugar-sweetened beverages consumption in Korea

Shim JS, Kang NH, Lee JS, Kim KN, Chung HK, Chung HR, Kim HJ, Ahn YS, Chang MJ

BACKGROUND/OBJECTIVES: Excessive sugar consumption may increase the risk for development of several diseases. Although average dietary sugar intake of Koreans is within the recommended level, an increasing trend has been...
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[¹⁸F]FET PET is a useful tool for treatment evaluation and prognosis prediction of anti-angiogenic drug in an orthotopic glioblastoma mouse model

Kim OS, Park JW, Lee ES, Yoo RJ, Kim WI, Lee KC, Shim JH, Chung HK

O-2-¹⁸F-fluoroethyl-l-tyrosine ([¹⁸F]FET) has been widely used for glioblastomas (GBM) in clinical practice, although evaluation of its applicability in non-clinical research is still lacking. The objective of this study was to...
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Differences in Dietary Life and Health related Factors According to Obesity in Poor Urban Peruvian Adolescents

Chung HK, Lee HY, Kim JR, Nam EW

OBJECTIVES: This study examined the differences in dietary life and health related factors, such as drinking behavior, exercise and leisure activities, mental health, and subjective perception for oneself according to...
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Ultrasonographic Assessment of the Pronator Quadratus Muscle after Surgical Treatment for Distal Radius Fractures

Choi DH, Chung HK, Lee JW, Kim CH, Choi YS

PURPOSE: This study was to assess the morphological changes of the pronator quadratus (PQ) muscle using an ultrasonography in the volar locking plate fixation group and in the percutaneous K-wire...
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Two Cases of Graves' Disease Presented with Atypical Symptoms

Yoo WS, Chung HK

We describe here two Graves' patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old...
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Effects of Activity-Based Personalized Nutrition Education on Dietary Behaviors and Blood Parameters in Middle-Aged and Older Type 2 Diabetes Korean Outpatients

Yang SH, Chung HK, Lee SM

This study aimed to compare the effects of activity-based personalized nutrition education (APNE) with a general instruction for diabetes (control, CTRL) in middle-aged and older Korean outpatients with type 2...
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Recent Advances in Autoimmune Thyroid Diseases

Yoo WS, Chung HK

Autoimmune thyroid disease (AITD) includes hyperthyroid Graves disease, hypothyroid autoimmune thyroiditis, and subtle subclinical thyroid dysfunctions. AITD is caused by interactions between genetic and environmental predisposing factors and results in...
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Alcohol Consumption and Diabetes Mellitus

Chung HK

The effects of alcohol consumption on diabetic patients are still unclear and inconclusive. Generally, light-to-moderate alcohol consumption (< 3 glasses) may have beneficial effects without disturbing glucose control. However, excessive...
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GDF15 Is a Novel Biomarker for Impaired Fasting Glucose

Hong JH, Chung HK, Park HY, Joung KH, Lee JH, Jung JG, Kim KS, Kim HJ, Ku BJ, Shong M

BACKGROUND: Growth differentiation factor-15 (GDF15) is a protein that belongs to the transforming growth factor beta superfamily. An elevated serum level of GDF15 was found to be associated with type...
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Effects of Diet Modification on Meal Quality and Quality of Life in Korean Diabetic Patients: Data from Korea National Health and Nutrition Examination Survey (2007-2011)

Cho Y, Shin MJ, Chung HK

It is generally accepted that diet modification provides beneficial effects on the management of diabetes. In the present study, we evaluated the effects of diet modification on nutrient intake and...
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