Korean J Orthod.  2014 May;44(3):113-118. 10.4041/kjod.2014.44.3.113.

Effects of various toothpastes on remineralization of white spot lesions

• Jo SY
• Chong HJ
• Lee EH
• Chang NY
• Chae JM
• Cho JH
• Kim SC
• Kang KH

• KMID: 1974996
• DOI: http://doi.org/10.4041/kjod.2014.44.3.113

Abstract

OBJECTIVE
The purpose of this in vitro study was to examine the effects of fluoridated, casein phosphopeptide.amorphous calcium phosphate complex (CPP-ACP)-containing, and functionalized beta-tricalcium phosphate (fTCP)-containing toothpastes on remineralization of white spot lesions (WSLs) by using Quantitative light-induced fluorescence (QLF-D) Biluminator(TM) 2.
METHODS
Forty-eight premolars, extracted for orthodontic reasons from 12 patients, with artificially induced WSLs were randomly and equally assigned to four treatment groups: fluoride (1,000 ppm), CPP-ACP, fTCP (with sodium fluoride), and control (deionized water) groups. Specimens were treated twice daily for 2 weeks and stored in saliva solution (1:1 mixture of artificial and human stimulated saliva) otherwise. QLF-D Biluminator(TM) 2 was used to measure changes in fluorescence, indicating alterations in the mineral contents of the WSLs, immediately before and after the 2 weeks of treatment.
RESULTS
Fluorescence greatly increased in the fTCP and CPP-ACP groups compared with the fluoride and control groups, which did not show significant differences.
CONCLUSIONS
fTCP- and CPP-ACP-containing toothpastes seem to be more effective in reducing WSLs than 1,000-ppm fluoride-containing toothpastes.

Keyword

Remineralization; Tooth paste; Cariology; White spot lesions; Tricalcium phosphate

MeSH Terms

Bicuspid
Calcium
Caseins
Dental Caries*
Fluorescence
Fluorides
Humans
Saliva
Sodium
Toothpastes*
Calcium
Caseins
Fluorides
Sodium
Toothpastes

Figure

• 

  Figure 1 Representative light-induced fluorescent images of the control group. Pretreatment (A) and post-treatment (B).

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  Figure 2 Representative light-induced fluorescent images of the fluoride group. Pretreatment (A) and post-treatment (B).

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  Figure 3 Representative light-induced fluorescent images of the casein phosphopeptide.amorphous calcium phosphate complex group. Pretreatment (A) and post-treatment (B).

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  Figure 4 Representative light-induced fluorescent images of the functionalized β-tricalcium phosphate group. Pretreatment (A) and post-treatment (B).

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