J Korean Neurol Assoc.  2004 Jun;22(3):265-268.

A Case of Lower Motor Neuron Syndrome Which May be Paraneoplastic

Affiliations
  • 1Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea. kkkim@amc.seoul.kr

Abstract

We present a 55-year-old man who has a six-month history of progressive weakness of all limbs. Findings from neurologic examination were notable for a diffuse muscular weakness and atrophy in all limbs. Laboratory findings for collagen vascular disease, monoclonal gammopathy, and infections were normal. Electrophysiologic studies supported lower motor neuron (LMN) syndrome. CT scan and needle biopsy disclosed small cell lung cancer. This case suggests that in some elderly patients with LMN syndrome a careful search for an underlying cancer is warranted.

Keyword

Paraneoplastic syndromes; Lower motor neuron disease; Lung cancer

MeSH Terms

Aged
Atrophy
Biopsy, Needle
Collagen
Extremities
Humans
Lung Neoplasms
Middle Aged
Motor Neuron Disease
Motor Neurons*
Muscle Weakness
Neurologic Examination
Paraneoplastic Syndromes
Paraproteinemias
Small Cell Lung Carcinoma
Tomography, X-Ray Computed
Vascular Diseases
Collagen
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