Korean J Med.  2002 Mar;62(3):307-312.

A case of acromegaly with mixed papillary-follicular thyroid carcinoma

• Lee CH
• Cheon NI
• Hong SI
• Chung JO
• Yoon IS
• Cho DH
• Kang HC
• Chung DJ
• Chung MY

Abstract

Patients with acromegaly have high incidence of benign or malignant neoplasia than general population and many investigators suggest the stimulatory effect of GH and IGF-1 on mesenchymal cells. Both normal thyroid tissue and thyroid cancer cells express IGF-1 receptor and thyroid cancer cells have more than 3 times. We present a case of acromegaly in patient with mixed papillary-follicular thyroid carcinoma, suggesting the possible carcinogenic role of GH and IGF-1.

Keyword

Acromegaly; Thyroid neoplasms

MeSH Terms

Acromegaly*
Humans
Incidence
Insulin-Like Growth Factor I
Receptor, IGF Type 1
Research Personnel
Thyroid Gland*
Thyroid Neoplasms*
Insulin-Like Growth Factor I
Receptor, IGF Type 1