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Emerging Nondopaminergic Medications for Parkinson’s Disease: Focusing on A2A Receptor Antagonists and GLP1 Receptor Agonists

Shang P, Baker M, Banks S, Hong SI, Choi DS

Parkinson’s disease (PD) is a severe neurodegenerative disease characterized by classic motor features associated with the loss of dopaminergic neurons and appearance of Lewy bodies in the substantia nigra. Due...
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The Prevalence and Emergency Department Utilization of Patients Who Underwent Single and Double Inter-hospital Transfers in the Emergency Department: a Nationwide Population-based Study in Korea, 2016–2018

Kim YJ, Hong JS, Hong SI, Kim JS, Seo DW, Ahn R, Jeong J, Lee SW, Moon S, Kim WY

Background: Inter-hospital transfer (IHT) for emergency department (ED) admission is a burden to high-level EDs. This study aimed to evaluate the prevalence and ED utilization patterns of patients who underwent...
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Rodent models for psychiatric disorders: problems and promises

Baker M, Hong SI, Kang S, Choi DS

Psychiatric disorders are a prevalent global health problem, over 900 million individuals affected by a continuum of mental and substance use disorders. Due to this high prevalence, and the substantial...
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Management of carbapenem-resistant Acinetobacter baumannii epidemic in an intensive care unit using multifaceted intervention strategy

Hong J, Jang OJ, Bak MH, Baek EH, Park KH, Hong SI, Cho OH, Bae IG

BACKGROUND/AIMS: We evaluated the effects of a multifaceted intervention for controlling a carbapenem-resistant Acinetobacter baumannii (CRAB) epidemic in an intensive care unit (ICU) with no restrictions on carbapenem use. METHODS: This...
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Screening and Evaluation of Streptomyces Species as a Potential Biocontrol Agent against a Wood Decay Fungus, Gloeophyllum trabeum

Jung SJ, Kim NK, Lee DH, Hong SI, Lee JK

Two-hundred and fifty-five strains of actinomycetes isolated from soil samples were screened for their antagonistic activities against four well-known wood decay fungi (WDF), including a brown rot fungus, Gloeophyllum trabeum...
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Successful Treatment of Catheter Related Blood Stream Infection By Millerozyma farinosa with Micafungin: A Case Report

Hong SI, Suh YS, Kim HO, Bae IG, Shin JH, Cho OH

Millerozyma farinosa (formerly Pichia farinosa) is halotolerant yeast mainly found in food and ubiquitous in the environment. It was a rare yeast pathogen, but it has recently emerged as a...
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Tuberculous Meningitis-Mimicking Varicella-Zoster Meningitis

Hong SI, Kim T, Jung J, Park SY, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Lee SA, Kim SH

BACKGROUND: Varicella-zoster virus (VZV) is one of the most common etiologies of aseptic meningitis. The severest manifestation of VZV meningitis is occasionally confused with tuberculous meningitis (TBM). Thus, we investigated...
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Quinpirole Increases Melatonin-Augmented Pentobarbital Sleep via Cortical ERK, p38 MAPK, and PKC in Mice

Hong SI, Kwon SH, Hwang JY, Ma SX, Seo JY, Ko YH, Kim HC, Lee SY, Jang CG

Sleep, which is an essential part of human life, is modulated by neurotransmitter systems, including gamma-aminobutyric acid (GABA) and dopamine signaling. However, the mechanisms that initiate and maintain sleep remain...
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Sensitivity of the Cytomegalovirus Antigenemia Assay to Diagnose Cytomegalovirus Retinitis

Hong SI, Kim T, Park SY, Jung J, Lee JY, Chong YP, Sung H, Lee SO, Choi SH, Kim YS, Woo JH, Kim SH

BACKGROUND: Cytomegalovirus (CMV) retinitis is one of the most important tissue-invasive CMV diseases in immunocompromised patients. Since 1980, non-invasive diagnostic methods, notably the CMV antigenemia assay, have been widely used...
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A Rare Case of Pediatric T Lymphoblastic Leukemia With t(11;17)(q23;q21) Involving Mixed-Lineage Leukemia Gene Rearrangement

Kim H, Lee JK, Lee JA, Hong YJ, Hong SI, Jo HS, Chang YH

No abstract available.
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Usefulness of Serum Thymidine Kinase 1 as a Biomarker for Aggressive Clinical Behavior in B-cell Lymphoma

Kim H, Kang HJ, Lee JK, Hong YJ, Hong SI, Chang YH

BACKGROUND: The cell cycle-dependent enzyme thymidine kinase 1 (TK1) is known to increase during cancer cell proliferation and has been reported as a prognostic marker for various hematologic malignancies and...
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Multiple Myeloma in a Patient with Acromegaly

Kang YM, Choi JH, Lee MJ, Ahn A, Park CJ, Chang K, Seo S, Hong SI, Kim MS

Acromegaly is a slowly progressing condition resulting from excess growth hormone (GH), generally caused by a GH-secreting pituitary adenoma. Cancer is the third most common cause of mortality in patients...
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Pyogenic Sacroiliitis Caused by Salmonella enterica Serotype Livingstone

Hong SI, Kim T, Yun JH, Cho DH, Kim YS, Woo JH, Kim SH

Pyogenic sacroiliitis is a rare joint infection, with a challenging diagnosis due to its nonspecific indicators and symptoms. Staphylococcus aureus is the most common causative bacteria of pyogenic sacroiliitis, with...
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Strain Differences in the Chronic Mild Stress Animal Model of Depression and Anxiety in Mice

Jung YH, Hong SI, Ma SX, Hwang JY, Kim JS, Lee JH, Seo JY, Lee SY, Jang CG

Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a...
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A Case of IgG4-Related Lung Disease Presenting as Interstitial Lung Disease

Ahn JH, Hong SI, Cho DH, Chae EJ, Song JS, Song JW

Intrathoracic involvement of immunoglobulin G4 (IgG4)-related disease has recently been reported. However, a subset of the disease presenting as interstitial lung disease is rare. Here, we report a case of...
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Comparison of Serum Fibrin-Fibrinogen Degradation Products with Carcinoembryonic Antigen as Biomarkers for Colon Cancer

So HJ, Hong SI, Lee JK, Chang YH, Kim JH, Hong YJ

  • KMID: 2200446
  • J Lab Med Qual Assur.
  • 2014 Jun;36(2):99-106.
BACKGROUND: Colon cancer is the second most common cancer in males and fourth most common in females in Korea. The levels of serum fibrin-fibrinogen degradation products (FDP) are elevated in...
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Clinical Characteristics and Survival of Korean Idiopathic Pulmonary Arterial Hypertension Patients Based on Vasoreactivity

Ahn JH, Kang BJ, Hong SI, Lee JS, Lee JS, Oh YM, Lee SD

We aimed to identify a vasoreactive subset of patients with idiopathic pulmonary arterial hypertension (IPAH) in Korea and to show their clinical characteristics and prognosis. Data on patients who were...
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A Case of Vertebral Osteomyelitis with Bacteremia and Psoas Abscess Caused by Non-typeable Haemophilus influenzae

Kim T, Hong SI, Yun JH, Park SY, Woo CY, Sung H, Choi SH

Vertebral osteomyelitis is primarily seen in middle-aged individuals, with a mean age of presentation of ~60 years. Recent trends suggest an increase in the incidence of vertebral osteomyelitis due to...
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Dependence Potential of Tramadol: Behavioral Pharmacology in Rodents

Cha HJ, Song MJ, Lee KW, Kim EJ, Kim YH, Lee Y, Seong WK, Hong SI, Jang CG, Yoo HS, Jeong HS

Tramadol is an opioid analgesic agent that has been the subject of a series of case reports suggesting potential for misuse or abuse. However, it is not a controlled substance...
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A Case of Hepatosplenic T-cell Lymphoma Diagnosed by Bone Marrow Examination

So HJ, Lee JK, Hong YJ, Hong SI, Kang HJ, Lee SS, Chang YH

  • KMID: 2312219
  • Lab Med Online.
  • 2013 Apr;3(2):104-109.
Hepatosplenic T-cell lymphoma (HSTL) is a condition in which lymphoma cells infiltrate the sinusoids of the liver, spleen, and bone marrow, without lymph node involvement. We encountered a case of...
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