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Anaplastic Transformation of Metastatic Papillary Thyroid Carcinoma in a Cervical Lymph Node: a Timeline and Short Review

Cinamon U, Horev Y, Vaknine H

Anaplastic thyroid cancer (ATC) is accepted as the transformation of a pre-existing glandular papillary thyroid carcinoma (PTC). Anaplastic transformation of a neck PTC metastasis in a lymph node is extraordinary....
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Modification of the Tumor-Node-Metastasis Staging System for Differentiated Thyroid Carcinoma by Considering Extra-Thyroidal Extension and Lateral Cervical Lymph Node Metastasis

Kim M, Kim WG, Jeon MJ, Kim HK, Yi HS, Kim ES, Kim BH, Kim WB, Shong YK, Kang HC, Kim TY

BACKGROUND: Concerns have arisen about the classification of extra-thyroidal extension (ETE) and lateral cervical lymph node metastasis (N1b) in the 8th edition of the tumor-node-metastasis staging system (TNM-8). This study...
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Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers

Yoo SK, Song YS, Park YJ, Seo JS

Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5...
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Unmet Clinical Needs in the Treatment of Patients with Thyroid Cancer

Kim WB, Jeon MJ, Kim WG, Kim TY, Shong YK

The increased incidence of thyroid cancer is a worldwide phenomenon; however, the issue of overdiagnosis has been most prominent in South Korea. The age-standardized mortality rate of thyroid cancer in...
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Occult papillary thyroid carcinoma presenting with cervical neck lymph node metastasis

Han S, Hong S, Lee J, Kim S, Baek MJ

A 74-year-old male patient was conducted total thyroidectomy with functional neck dissection and final pathologic report confirm occult thyroid carcinoma. Although the frequency of occult thyroid cancer (OTC) has decreased...
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Intrathyroidal Parathyroid Carcinoma in Chronic Kidney Disease: A Case Report and Review of Literature

Kim MK, Song CM, Tae K, Ji YB

When parathyroid carcinoma occurs in the thyroid gland, it is very difficult to diagnose before surgery because imaging studies and aspiration cytology cannot distinguish parathyroid carcinoma from thyroid nodule or...
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Cervical Bronchogenic Cysts Mimicking Papillary Thyroid Carcinoma on Ultrasound

Ahn D, Kim JK

Here, we describe two cases of cervical bronchogenic cysts mimicking thyroid cancer on ultrasound (US), introducing some sources of diagnostic error with the aim of improving the understanding of cervical...
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68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?

Lengana T, Lawal IO, Mokoala K, Vorster M, Sathekge M

We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of...
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Efficacy of Percutaneous Thermal Ablation of Papillary Thyroid Carcinoma

Caruso E, Gagliano E, Dionigi G

Percutaneous thermoablation (PTA) has become an increasingly used option in the interventional treatment of symptomatic, cytologic and sonographic benign solid thyroid gland disease. Currently, there is no high-level evidence of...
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The Incidence and Clinicopathologic Characteristics of Patients Who Had False-Positive Fine-Needle Aspiration Results for Papillary Thyroid Cancer

Bang Y, Back K, Kim JH, Choe J, Kim JS

PURPOSE: Fine needle aspiration (FNA) is a well-established method for diagnosis of thyroid tumors. However, FNA sometimes fails to distinguish benign thyroid nodules from papillary thyroid carcinoma (PTC). The aim...
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Relationship between Initial Thyroid Operation and the Location of Locoregional Recurrence in Papillary Thyroid Cancer: a Single Tertiary Center Experience

Rah CS, Chang JG, Kim WW, Lee YM, Jeon MJ, Song DE, Choi YJ, Chung KW, Hong SJ, Sung TY

PURPOSE: Locoregional recurrence of papillary thyroid cancer (PTC) after initial thyroid operation is frequent in high-risk patients. However, many studies have reported on risk factors for recurrence without presenting the...
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Which Clinicopathological Factors Are Related to Tumor Size in Papillary Thyroid Cancer?

Yoon S, Lee J, Soh E

PURPOSE: Papillary thyroid cancer (PTC) is the most common endocrine cancer worldwide. Tumor size on observation, together with lymph node metastasis, serves as a determinant of surgery. However, not all...
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Parathyroid Adenoma Causing Spontaneous Cervical Hematoma: A Case Report and Review of Literature

Shin TH, Park SS, Won CS, Kim MK, Kim MS

Parathyroid adenoma can cause extracapsular bleeding. In 1934, Capps first reported a case of massive hemorrhage secondary to rupture of a parathyroid adenoma. Recently, we experienced a 73-year-old female presented...
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The Cause of Cervical Lymph Node Recurrence after the Initial Surgery of Papillary Thyroid Carcinoma

Kim HK, Ha EJ, Lee I, Lee J, Soh EY

BACKGROUND/OBJECTIVES: Papillary thyroid carcinoma (PTC) has generally an indolent character with a good prognosis. However, recurrence remains a major concern for the patients during their lifetime. Despite the slowly progressing...
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A Multi-institutional Study of Prevalence and Clinicopathologic Features of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) in Korea

Seo JY, Park JH, Pyo JY, Cha YJ, Jung CK, Song DE, Kwak JJ, Park SY, Na HY, Kim JH, Seok JY, Kim HS, Hong SW

BACKGROUND: In the present multi-institutional study, the prevalence and clinicopathologic characteristics of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) were evaluated among Korean patients who underwent thyroidectomy for...
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A Case of Severe Pneumocystis Pneumonia in a Thyroid Cancer Patient Receiving Lenvatinib

Jin MH, Kim WG, Kim TY, Kim WB, Shong YK, Jeon MJ

Lenvatinib is a multitargeted tyrosine kinase inhibitor approved for use in patients with iodine-131–refractory thyroid cancer. The common adverse events of lenvatinib include hypertension, proteinuria, fatigue, and diarrhea. To date,...
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Hemi-Thyroidectomy versus Total Thyroidectomy in Patients with Low-Risk Papillary Thyroid Carcinoma Sized 2 cm or Less

Park HS, Lee HS, Sung JH, Hwang HJ, Kim SW, Lee KD

BACKGROUND AND OBJECTIVES: The controversy over the optimal extent of thyroidectomy for papillary thyroid carcinoma (PTC) has persisted over a long time period. Particularly, there is a lack of consensus...
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Factors Affecting Postoperative Occupational Changes and Sick Leave in Patients with Thyroid Cancer

Park KA, Oh YJ, Chu SH, Lee YS, Chang HS, Park CS

BACKGROUND AND OBJECTIVES: Most thyroid cancers progress slowly, have high survival rates, and have good prognosis. Therefore, the management of patients with thyroid cancer should be viewed from a long-term...
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Differentiated Thyroid Cancer and Radioactive Iodine: Past, Present and Future

Lee J, Jo I

Radioiodine has been known as an important and safe armamentarium in the diagnosis and treatment of differentiated thyroid cancer (DTC) for more than 70 years. The 2015 guidelines from the...
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Pleuropericardial Cyst Mimicking a Metastasis of Differentiated Thyroid Carcinoma on Whole-Body Iodine-131 Scan: a Case Report

Bourogianni O, Pagonidis , Stathaki M, Tsaroucha , Papadaki E, Koukouraki S

Post-therapeutic whole-body scan (WBS) with I-131 has been widely used for the follow-up of patients with well-differentiated thyroid cancer (DTC). Although the sensitivity of WBS with I-131 in detection of...
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