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Repeated Low High-Density Lipoprotein Cholesterol and the Risk of Thyroid Cancer: A Nationwide Population- Based Study in Korea

Kim J, Kim MK, Baek KH, Song KH, Han K, Kwon HS

Background: High-density lipoprotein cholesterol (HDL-C) plays an important role in the reverse cholesterol transport pathway and prevents atherosclerosis-mediated disease. It has also been suggested that HDL-C may be a protective...
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Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)

Lee Jy, Kim SY, Jo KH, Mo EY, Kim ES, Kim HS, Han JH, Moon Sd

Background/Aims: Germline mutations of the rearranged during transfection (RET) gene cause multiple endocrine neoplasia type 2 (MEN2). About 85% of RET mutations in MEN2 occur in codon Cys634. The RET...
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Diagnostic Performance of Thyroid Core Needle Biopsy Using the Revised Reporting System: Comparison with Fine Needle Aspiration Cytology

Kim K, Bae JS, Kim JS, Jung SL, Jung CK

Background: We aim to validate the diagnostic performance of thyroid core needle biopsy (CNB) for diagnosing malignancy in clinical settings to align with the changes made in recently updated thyroid...
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Development of Metabolic Synthetic Lethality and Its Implications for Thyroid Cancer

Ju SH, Lee SE, Kang YE, Shong M

Cancer therapies targeting genetic alterations are a topic of great interest in the field of thyroid cancer, which frequently harbors mutations in the RAS, RAF, and RET genes. Unfortunately, U.S....
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Care and Management of Voice Change in Thyroid Surgery: Korean Society of Laryngology, Phoniatrics and Logopedics Clinical Practice Guideline

Korean Society of Laryngology, Phoniatrics and Logopedics Guideline Task Force, Ryu CH, Lee SJ, Cho JG, Choi IJ, Choi YS, Hong YT, Jung SY, Kim JW, Lee DY, Lee DK, Lee G, Lee SJ, Lee YC, Lee YS, Nam IC, Park KN, Park YM, Sung ES, Son HY, Seo IH, Lee BJ, Lim JY

Voice change is a common complaint after thyroid surgery and has a significant impact on quality of life. The Korean Society of Laryngology, Phoniatrics and Logopedics assembled a task force...
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Reduced Port Robotic Bilateral Axillo-Breast Approach (BABA) Isthmusectomy

Kim W, Lee JK, Choi JH, Yu HW, Kim Sj, Chai YJ, Choi JY, Lee KE

Purpose: To investigate whether reduced port robotic bilateral axillo-breast approach (BABA) surgery can be a safe alternative approach for patients undergoing isthmusectomy for well differentiated papillary thyroid cancer confined to...
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Association between breastfeeding and breast, thyroid, and cervical cancer among Korean adult women based on the Korean Genome and Epidemiology Study: a cohort study

Jin E, Kang H, Son M

Purpose: The purpose of this study was to explore the relationship between breastfeeding and the prevalence of breast, thyroid, and cervical cancer among Korean adult women. Methods: The study was a...
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Clinical Characteristics and Prognosis of Coexisting Thyroid Cancer in Patients with Graves’ Disease: A Retrospective Multicenter Study

Yoon JH, Jin M, Kim M, Hong AR, Kim HK, Kim BH, Kim WB, Shong YK, Jeon MJ, Kang HC

Background: The association between Graves’ disease (GD) and co-existing thyroid cancer is still controversial and most of the previously reported data have been based on surgically treated GD patients. This...
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Hormonal Replacement Therapy and Risk of Thyroid Cancer in Women: A Meta-Epidemiological Analysis of Prospective Cohort Studies

Bae JM

Objectives: Many experimental studies have reported that female sex hormones involve thyroid cancer development because the incidence rate of thyroid cancer in women (TCW) is 3 times higher than in...
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Serum Carcinoembryonic Antigen as a Biomarker for Medullary Thyroid Cancer

Kim J, Park H, Choi MS, Park J, Jang HW, Kim TH, Kim SW, Chung JH

Background and Objectives: The lack of known elevated biomarkers in cancer surveillance is a challenge for diagnostics. However, few studies have assessed the proportion of patients with medullary thyroid cancer...
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Thyroid Lobectomy as an Initial Treatment Option on 1-4 cm Papillary Cancer

Cho JS

Recently, the early diagnosis and treatment of differentiated thyroid cancer has significantly increased the proportion of thyroid lobectomy rather than total thyroidectomy. Thyroid lobectomy is recommended for less than 1...
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Comparison of Korean vs. American Thyroid Imaging Reporting and Data System in Malignancy Risk Assessment of Indeterminate Thyroid Nodules

Kang S, Kwon SK, Choi HS, Kim MJ, Park YJ, Park DJ, Cho SW

Background: The management of cytologically indeterminate thyroid nodules is challenging for clinicians. This study aimed to compare the diagnostic performance of the Korean Thyroid Imaging Reporting and Data Systems (K-TIRADS)...
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Comparison of the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy with three international guidelines

Ha EJ, Shin JH, Na DG, Jung SL, Lee YH, Paik W, Hong MJ, Kim YK, Lee CY

Purpose: This study compared the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS) for thyroid malignancy with three international guidelines. Methods: From June to September 2015,...
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Diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System for thyroid malignancy according to nodule size: a comparison with five society guidelines

Na DG, Paik W, Cha J, Gwon HY, Kim SY, Yoo RE

Purpose: The aim of this study was to evaluate the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS) compared with five society risk stratification systems...
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Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis

Lee J, Cho Y, Choi KH, Hwang I, Oh YL

Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple...
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Proto-oncogene Pokemon in thyroid cancer: a potential promoter of tumorigenesis in papillary thyroid carcinoma

Chang K, Do SI, Kim K, Chae SW, Do Ig, Lee HJ, Kim DH, Sohn JH

Background: Pokemon is an oncogenic transcription regulator that plays a critical role in cellular differentiation. Although it has been found to be overexpressed in several types of cancer involving different...
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The Concept of Economic Evaluation and Its Application in Thyroid Cancer Research

Kim K, Kim M, Lim W, Kim BH, Park SK

Economic evaluation is a type of comparative analysis between interventions in terms of both their resource use and health outcomes. Due to the good prognosis of thyroid cancer (TC), the...
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Active Surveillance as an Effective Management Option for Low-Risk Papillary Thyroid Microcarcinoma

Jeon MJ, Kim WG, Kim TY, Shong YK, Kim WB

Active surveillance (AS) for low-risk papillary thyroid microcarcinoma (PTMC) has been accepted worldwide as safe and effective. Despite the growing acceptance of AS in the management of low-risk PTMCs, there...
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A Case of Intrathyroidal Parathyroid Carcinoma Accompanied by Contralateral Parathyroid Hyperplasia

Koo BM, Moon SK, Lee MJ, Kim SW

Parathyroid carcinoma accounts for about 0.5%-5% of all parathyroid neoplasms. Very rarely, but if the intrathyroidal parathyroid gland is present, the carcinoma can arise in that developmental anomaly. It is...
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Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea

Hoang T, Song D, Lee J, Lee EK, Hwangbo Y, Kim J

Purpose Obesity has been determined to be associated with fat mass and obesity-associated (FTO) gene and thyroid cancer risk. However, the effect of combined interactions between obesity and the FTO gene...
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