Korean J Obstet Gynecol.  2012 Jan;55(1):47-50. 10.5468/KJOG.2012.55.1.47.

Primary yolk sac tumor of omentum: A case report

• Kwon DY
• Yu YS
• Baek SH
• Choi SC
• Ryu SY

• KMID: 1836764
• DOI: http://doi.org/10.5468/KJOG.2012.55.1.47

Abstract

Yolk sac tumor (YST) is one of the rare malignant germ cell tumor and usually occurs in gonad. Extragondal sites of YSTs are reported in mediastinum, vagina, brain, and retroperitoneum but are extremely rarely in omentum. The clinicopathologic feature of primary omental YST is not well known and there are only 5 cases reported currently. Recently we experienced a primary YST of omentum in 27-year-old woman who was performed exploratory laparotomy due to abdominal distension and pain. She has remained free of diseases for 2 years with normal menstruation after the fertility-saving surgery and postoperative adjuvant chemotherapy with bleomycin, etoposide, cisplatin regimen. The subject of primary YST of omentum is reviewed, and the possible histogenesis of the tumor is discussed.

Keyword

Yolk sac tumor; Germ cell tumor; Omentum

MeSH Terms

Adult
Bleomycin
Brain
Chemotherapy, Adjuvant
Cisplatin
Endodermal Sinus Tumor
Etoposide
Female
Gonads
Humans
Laparotomy
Mediastinum
Menstruation
Neoplasms, Germ Cell and Embryonal
Omentum
Vagina
Yolk Sac
Bleomycin
Cisplatin
Etoposide

Figure

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  Fig. 1 Computerised tonography showed a large lobulating abdominal mass infiltrating the omentum with small amount of ascites.

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  Fig. 2 Gross feature of specimen showed a multinodularomental mass measuring 13.5×13×7 cm. The cut surface is white, soft, hemorrhagic, and partly necrotic.

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  Fig. 3 Histological evaluation of the specimen shows typical Schiller Duval bodies (arrows) in microcystic area (A, H&E, ×200) and hyaline globules (arrows) (B, H&E, ×400). Special immunohistochemical staining of the tumor showed positive for AFP (C, immunohistochemical staining, ×400).

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