Infect Chemother.  2004 Feb;36(1):50-53.

A Case of Progressive Multifocal Leukoencephalopathy in a Patient with Acquired Immune Deficiency Syndrome

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. jmkim@yumc.yonsei.ac.kr
  • 2AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Abstract

In Korea, as the prevalence of acquired immune deficiency syndrome (AIDS) increases, various opportunistic infections are becoming a problem. Progressive multifocal leukoencephalopathy (PML) is postulated to be associated with impaired cellular immunity and can be more frequently encountered these days primarily due to increasing incidence of AIDS. Neurologic deficits and brain imaging study together strongly suggest PML, but confirmatory diagnosis can be made only by cerebrospinal fluid study or tissue biopsy. In Korea few cases of confirmed PML in AIDS patients have been reported, and herein we offer our experience of a case of PML who underwent brain biopsy for confirmative diagnosis.

Keyword

Progressive multifocal leukoencephalopathy; AIDS; HIV

MeSH Terms

Acquired Immunodeficiency Syndrome*
Biopsy
Brain
Cerebrospinal Fluid
Diagnosis
HIV
Humans
Immunity, Cellular
Incidence
Korea
Leukoencephalopathy, Progressive Multifocal*
Neuroimaging
Neurologic Manifestations
Opportunistic Infections
Prevalence
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