J Bacteriol Virol.  2012 Jun;42(2):172-176. 10.4167/jbv.2012.42.2.172.

Neutrophils in Immunity

• Woo SY

• KMID: 1717689
• DOI: http://doi.org/10.4167/jbv.2012.42.2.172

Abstract

Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins, and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.

Keyword

Inflammation; Antimicrobial; Granule; Neutrophil extracellular trap (NET)

MeSH Terms

Autoimmunity
Cytokines
Inflammation
Leukocytes
Neutrophils
Phagocytes
Proteins
Cytokines
Proteins

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