- IL-17-Producing Cells in Tumor Immunity: Friends or Foes?
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Kuen DS, Kim BS, Chung Y
- KMID: 2471046
- Immune Netw.
- 2020 Feb;20(1):e6.
- doi: 10.4110/in.2020.20.e6
IL-17 is produced by RAR-related orphan receptor gamma t (RORγt)-expressing cells including Th17 cells, subsets of γδT cells and innate lymphoid cells (ILCs). The biological significance of IL-17-producing cells is... -
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- Systemic Sclerosis and Microbiota: Overview of Current Research Trends and Future Perspective
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Kim S, Chun SH, Park HJ, Lee SI
- KMID: 2459448
- J Rheum Dis.
- 2019 Oct;26(4):235-247.
- doi: 10.4078/jrd.2019.26.4.235
The commensal microbiota contributes to the maintenance of immune homeostasis in the human body. Autoimmunity can be aggravated or alleviated by the microbiota, which affects both innate and adaptive immune... -
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- The Association between Low Vitamin D Status and Autoimmune Thyroid Disease in Korean Premenopausal Women: The 6th Korea National Health and Nutrition Examination Survey, 2013–2014
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Kim CY, Lee YJ, Choi JH, Lee SY, Lee HY, Jeong DH, Choi YJ
- KMID: 2459570
- Korean J Fam Med.
- 2019 Sep;40(5):323-328.
- doi: 10.4082/kjfm.18.0075
BACKGROUND: This study aimed to analyze the association of low vitamin D status with thyroid autoimmunity and dysfunction in the Korean population according to sex and menopausal status in women. METHODS:... -
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- Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata
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Zhang L, Xu X, Chen S, Kang Y, Wang X, Zhang C, Xiang L
- KMID: 2451476
- Ann Dermatol.
- 2019 Aug;31(4):393-402.
- doi: 10.5021/ad.2019.31.4.393
BACKGROUND: Vitiligo is a common acquired pigmentary disease caused by destruction of epidermal melanocytes in underlying autoimmune response. Few studies have been focused on the role of chemokines in non-segmental... -
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- Autoimmune Diseases and Gastric Cancer Risk: A Systematic Review and Meta-Analysis
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Song M, Latorre G, Ivanovic-Zuvic D, Camargo MC, Rabkin CS
- KMID: 2454277
- Cancer Res Treat.
- 2019 Jul;51(3):841-850.
- doi: 10.4143/crt.2019.151
PURPOSE: Autoimmunity is an alternative etiology of gastric inflammation, the initiating event in the gastric carcinogenic cascade. This mechanism may be an increasingly important cause of gastric cancer with the... -
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- Progression of Multifaceted Immune Cells in Atherosclerotic Development
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Park S, Lee IK
- KMID: 2447753
- J Lipid Atheroscler.
- 2019 May;8(1):15-25.
- doi: 10.12997/jla.2019.8.1.15
Atherosclerosis is a major cause of morbidity and mortality due to cardiovascular diseases, such as coronary artery disease, stroke, and peripheral vascular disease, that are associated with thrombosis-induced organ infarction.... -
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- Sputum Autoantibodies Are More Relevant in Autoimmune Responses in Asthma than Are Serum Autoantibodies
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Qin R, Long F, Xiao X, Xiao J, Zheng Z, Feng M, Huang R, Peng T, Li J
- KMID: 2442051
- Allergy Asthma Immunol Res.
- 2019 May;11(3):406-421.
- doi: 10.4168/aair.2019.11.3.406
PURPOSE: The data on the differences between sputum autoantibodies (Sp-Abs) and serum autoantibodies (Se-Abs) in reflection of autoimmune responses to lungs is still lacking. METHODS: Ten types of Abs were investigated... -
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- Structural Characteristics of Seven IL-32 Variants
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Sohn DH, Nguyen TT, Kim S, Shim S, Lee S, Lee Y, Jhun H, Azam T, Kim J, Kim S
- KMID: 2444156
- Immune Netw.
- 2019 Apr;19(2):e8.
- doi: 10.4110/in.2019.19.e8
IL-32 exists as seven mRNA transcripts that can translate into distinct individual IL-32 variants with specific protein domains. These translated protein domains of IL-32 variants code for specific functions that... -
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- Aged Sanroque Mice Spontaneously Develop Sjögren's Syndrome-like Disease
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Choi SS, Jang E, Oh YK, Jang K, Cho ML, Park SH, Youn J
- KMID: 2438915
- Immune Netw.
- 2019 Feb;19(1):e7.
- doi: 10.4110/in.2019.19.e7
Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disorder that affects mainly salivary and lacrimal glands, but its cause remains largely unknown. Clinical data indicating that SS occurs in a... -
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- Potential Implications of Long Noncoding RNAs in Autoimmune Diseases
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Hur K, Kim SH, Kim JM
- KMID: 2438912
- Immune Netw.
- 2019 Feb;19(1):e4.
- doi: 10.4110/in.2019.19.e4
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs of more than 200 nucleotides in length. Despite the term “noncodingâ€, lncRNAs have been reported to be involved in gene expression. Accumulating... -
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- Age-related Autoimmune Changes in Lacrimal Glands
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de Souza R, de Paiva C, Alves MR
- KMID: 2438911
- Immune Netw.
- 2019 Feb;19(1):e3.
- doi: 10.4110/in.2019.19.e3
Aging is a complex process associated with dysregulation of the immune system and low levels of inflammation, often associated with the onset of many pathologies. The lacrimal gland (LG) plays... -
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- CD72 is a Negative Regulator of B Cell Responses to Nuclear Lupus Self-antigens and Development of Systemic Lupus Erythematosus
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Tsubata T
- KMID: 2438909
- Immune Netw.
- 2019 Feb;19(1):e1.
- doi: 10.4110/in.2019.19.e1
Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease characterized by production of autoantibodies to various nuclear antigens and overexpression of genes regulated by IFN-I called IFN signature. Genetic... -
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- Causal Relationship Between Anti-TPO IgE and Chronic Urticaria by In Vitro and In Vivo Tests
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Sánchez J, Sánchez A, Cardona R
- KMID: 2426783
- Allergy Asthma Immunol Res.
- 2019 Jan;11(1):29-42.
- doi: 10.4168/aair.2019.11.1.29
PURPOSE: Immunoglobulin (Ig) E autoantibodies against thyroid antigens such as thyroid peroxidase (TPO) have been demonstrated in chronic spontaneous urticaria (CSU) patients in higher frequency than healthy subjects. However, if... -
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- Agreement of three commercial anti-extractable nuclear antigen tests: EUROASSAY Anti-ENA Profile, Polycheck Autoimmune Test and FID(IS) Connective Profile
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Kim N, Kim IS, Chang CL, Kim HH, Lee EY
- KMID: 2442541
- Kosin Med J.
- 2018 Dec;33(3):307-317.
- doi: 10.7180/kmj.2018.33.3.307
BACKGROUND: Detection of antibodies to extractable nuclear antigens (ENAs) is needed for the diagnosis in systemic autoimmune diseases. In this study, we compared three reagents using line immunoblot assay (LIA)... -
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- Vitiligo in a Patient with Systemic Lupus Erythematosus: A Case Report
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Kwon HI, Oh EH, Jung YD, Ko JY
- KMID: 2437055
- Korean J Dermatol.
- 2018 Dec;56(10):620-623.
Vitiligo is a multifactorial disorder. Neural, biochemical, and autoimmune mechanisms have been hypothetically suggested as etiopathological contributors to this condition. Autoimmunity focuses primarily on genetic factors and the association between... -
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- Concurrence of Circumscribed Morphea and Segmental Vitiligo: A Case Report
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Lee JS, Park HS, Cho S, Yoon HS
- KMID: 2428928
- Ann Dermatol.
- 2018 Dec;30(6):708-711.
- doi: 10.5021/ad.2018.30.6.708
Although a few reports have noted the concurrent presentation of morphea and vitiligo at distinctly separate sites in the same patient, it is extremely rare that these two conditions occur... -
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- Clinical implications of anti-thyroglobulin antibody measurement before surgery in thyroid cancer
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Jo K, Lim DJ
- KMID: 2426387
- Korean J Intern Med.
- 2018 Nov;33(6):1050-1057.
- doi: 10.3904/kjim.2018.289
Thyroglobulin antibody (TgAb) is a class G immunoglobulin and a conventional marker for thyroid autoimmunity. From a clinical perspective, TgAb is less useful than thyroid peroxidase antibodies for predicting thyroid... -
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- Decreased Expression of Sphingosine-1-Phosphate Receptor 1 in the Blood Leukocyte of Rheumatoid Arthritis Patients
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Choi HS, Kim KH, Jin S, Kim J, Yoo I, Pack SP, Ha UH, Park TW, Choi SA, Yuk SH, Kang SW, Jung YW
- KMID: 2424205
- Immune Netw.
- 2018 Oct;18(5):e39.
- doi: 10.4110/in.2018.18.e39
Sphingosine-1-phosphate (S1P) plays an important role in trafficking leukocytes and developing immune disorders including autoimmunity. In the synovium of rheumatoid arthritis (RA) patients, increased expression of S1P was reported, and... -
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- Clinical characteristics in Japanese children with nonobese type 2 diabetes
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Urakami T
- KMID: 2422473
- Ann Pediatr Endocrinol Metab.
- 2018 Sep;23(3):113-118.
- doi: 10.6065/apem.2018.23.3.113
It is well known that the incidence of youth-onset type 2 diabetes is increasing worldwide. On the other hand, most studies have shown that the majority of youth-onset type 2... -
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- Immune checkpoint inhibitors for urothelial carcinoma
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Kim HS, Seo HK
- KMID: 2419411
- Investig Clin Urol.
- 2018 Sep;59(5):285-296.
- doi: 10.4111/icu.2018.59.5.285
Urothelial carcinoma (UC), originating in the bladder or upper urinary tract, is the most common histological type of cancer. Currently, platinum-based cytotoxic chemotherapy is the standard treatment for metastatic UC... -
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