J Korean Pediatr Soc.
1978 Dec;21(12):1125-1137.
A clinicostatistical study of renal diseases in childhood
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Seoul National University, Korea.
Abstract
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A clinicostatistical study was done on 282 cases of renal diseases which were admitted in the pediatric ward of S.N.U.H., during the 5 years from Jan. 1973 to Dec. 1977.
The results were as follows.
1. During the 5 years, 282 cases of renal diseases were observed, which represents about 7.3% of total 3840 admitted cases during the same period.
2. Among the renal diseases in children, acute glomerulonephritis was the commonest renal disease showing 35.8% with 101 cases, and nephrotic syndrome (33.6%: 95 cases), chronic renal failure (7.4%:21 cases), acute pyelonephritis(4.2%:12cases) and others, in given order of frequency. (Table I -2)
3. The age distribution showed higher frequency in the age of 4~9 than that in the other age group. (Table I -3)
4. 36% of cases were noted in the autumn, 24% in the winter, 22% in the spring and 18% in the summer.
5. Fatal renal diseases were observed in 5 cases of chronic renal failure, 2 cases of nephrotic syndrome and 1 cases of polycystic kidney.
6. In acute glomerulonephritis, the highest incidence by age was noted 34.6% in the age groups of 7~9, and more than 80% of cases were observed in the autumn and the winter. Complications of acute glomerulonephritis were in the order of hypertensive encephalopathy (15 cases: 16.3%), congestive heart failure (9 cases: 9.8%) and acute renal failure(10 cases : 10.8%).
7. Among 25 cases of Henoch-Schonlein purpura which were observed during the same period, 10 cases (40%) showed renal involvement.
8. Among 12 cases of acute pyelonephritis, Escherichia coli was the commonest causative agent showing in 7 cases, which was sensitive to gentamycin and resistent to ampicillin in sensitivity test.
9. Among 5 cases of recurrent gross hematuria, percutaneous renal biopsy was performed in 4 cases. Histopathologic findings were variable, being diffuse mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, focal glomerulonephritis and focal glomerulosclerosis respectively in each case.