J Korean Pediatr Soc.  1978 Dec;21(12):1125-1137.

A clinicostatistical study of renal diseases in childhood

Affiliations
  • 1Department of Pediatrics, College of Medicine, Seoul National University, Korea.

Abstract

A clinicostatistical study was done on 282 cases of renal diseases which were admitted in the pediatric ward of S.N.U.H., during the 5 years from Jan. 1973 to Dec. 1977. The results were as follows. 1. During the 5 years, 282 cases of renal diseases were observed, which represents about 7.3% of total 3840 admitted cases during the same period. 2. Among the renal diseases in children, acute glomerulonephritis was the commonest renal disease showing 35.8% with 101 cases, and nephrotic syndrome (33.6%: 95 cases), chronic renal failure (7.4%:21 cases), acute pyelonephritis(4.2%:12cases) and others, in given order of frequency. (Table I -2) 3. The age distribution showed higher frequency in the age of 4~9 than that in the other age group. (Table I -3) 4. 36% of cases were noted in the autumn, 24% in the winter, 22% in the spring and 18% in the summer. 5. Fatal renal diseases were observed in 5 cases of chronic renal failure, 2 cases of nephrotic syndrome and 1 cases of polycystic kidney. 6. In acute glomerulonephritis, the highest incidence by age was noted 34.6% in the age groups of 7~9, and more than 80% of cases were observed in the autumn and the winter. Complications of acute glomerulonephritis were in the order of hypertensive encephalopathy (15 cases: 16.3%), congestive heart failure (9 cases: 9.8%) and acute renal failure(10 cases : 10.8%). 7. Among 25 cases of Henoch-Schonlein purpura which were observed during the same period, 10 cases (40%) showed renal involvement. 8. Among 12 cases of acute pyelonephritis, Escherichia coli was the commonest causative agent showing in 7 cases, which was sensitive to gentamycin and resistent to ampicillin in sensitivity test. 9. Among 5 cases of recurrent gross hematuria, percutaneous renal biopsy was performed in 4 cases. Histopathologic findings were variable, being diffuse mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, focal glomerulonephritis and focal glomerulosclerosis respectively in each case.


MeSH Terms

Age Distribution
Ampicillin
Biopsy
Child
Escherichia coli
Gentamicins
Glomerulonephritis
Glomerulonephritis, Membranoproliferative
Glomerulosclerosis, Focal Segmental
Heart Failure
Hematuria
Humans
Hypertensive Encephalopathy
Incidence
Kidney Failure, Chronic
Nephrotic Syndrome
Polycystic Kidney Diseases
Purpura, Schoenlein-Henoch
Pyelonephritis
Ampicillin
Gentamicins
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