Korean J Nutr.  2003 Oct;36(8):834-840.

Improve Effects of Saengshik on Patient with Fatty Liver and Hyperlipidemia in Murine

• Song MK
• Hong SG
• Hwang SJ
• Park OJ
• Park MH

Abstract

To examine the effect of Saengshik on parameters related to hepatoprotective, anthropometric, blood pressure, serum lipid and blood related indices, nonalcoholic fatty liver subjects were treated with two meal portion of Saengshik in the replacement of meals for a period of three months. Weight, Body Mass Index (BMI) and systolic blood pressure were significantly decreased after the treatment. Chronically elevated serum aspartate aminotransferase (AST), gamma-Glutamyl transferase (r-GTP) and Alkaline Phosphatase (ALP) levels showed reduction to the near normal range. Serum total triglyceride level were reduced following the treatment. Whereas, there were no changes of serum total cholesterol with Saengshik consumption. Also, additional study was conducted to investigate the effect of Saengshik supplementation to high cholesterol and fat diet on lipid metabolism in rats. Male Spraque-Dawley rats were administrated hyperlipidemiainducing diet containing 1% cholesterol and 10% lard to induce hyperlipidemia for 4 weeks and were fed on diet containing Saengshik (30%, w/w) for 7 weeks. The feeding of diet containing 30% Shaengshik significantly decreased total cholesterol (TC) contents and total triglyceride. These results demonstrate Saengshik may be beneficial for fatty liver patients in improving their lipid metabolism.

Keyword

uncooked natural food; fatty liver; hyperlipidemia; cholesterol

MeSH Terms

Alkaline Phosphatase
Animals
Aspartate Aminotransferases
Blood Pressure
Body Weight
Cholesterol
Diet
Fatty Liver*
Humans
Hyperlipidemias*
Lipid Metabolism
Male
Meals
Rats
Reference Values
Transferases
Triglycerides
Alkaline Phosphatase
Aspartate Aminotransferases
Cholesterol
Transferases