J Korean Pediatr Soc.
2001 Jun;44(6):709-713.
Three Cases of Urine Abnormalities Associated with Ketogenic Diet
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
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Ketogenic diet is a high-fat, low carbohydrate, low protein diet used in treatment of pediatric epilepsy
since the 1920s. Currently it is used primarily to treat refractory childhood epilepsy. Few serious
complications caused by ketogenic diet have been reported. Short-term complications include dehydration,
hypoglycemia, vomiting, diarrhea, and refusal to eat. Long-term complications include kidney stones,
recurrent infections, metabolic derangement, hypercholesterolemia, irritability, lethargy, and refusal to eat.
We experienced 3 cases of infantile spasm patients, whose refractory seizures were controlled with
ketogenic diet, but various urinary abnormalities developed.