J Korean Pediatr Soc.  2003 Nov;46(11):1131-1134.

A Case of Infantile Spasm Associated with Acute Renal Failure and Kwashiorkor after Ketogenic Diet

• Kim YM
• Kim TH
• Jung JA
• Hwang KG

Abstract

The ketogenic diet is a high-fat, low-protein, low-carbohydrate diet developed in the 1920s for the treatment of difficult-to-control seizures. Despite advances in both the pharmacotherapy and the surgery of epilepsy, many children continue to have difficult-to-control seizures. In this situation, a ketogenic diet should be considered as an alternative therapy. However, less attention has been paid to associated adverse events in the ketogenic diet. We report a case of infantile spasm associated with acute renal failure, lipoid pneumonitis and kwashiorkor after ketogenic diet. A better understanding of this adverse event profile will allow the pediatric neurologist to have a true informed consent discussion with the care giver when considering initiation of the ketogenic diet.

Keyword

Ketogenic diet; Acute renal failure; Kwashiorkor

MeSH Terms

Acute Kidney Injury*
Caregivers
Child
Diet
Drug Therapy
Epilepsy
Humans
Infant
Infant, Newborn
Informed Consent
Ketogenic Diet*
Kwashiorkor*
Pneumonia
Seizures
Spasms, Infantile*