J Korean Rheum Assoc.
2006 Jun;13(2):95-106.
Mesenchymal Stem Cells for Tissue Engineering and Regenerative Medicine
- Affiliations
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- 1Department of Orthopaedics, Dongguk University International Hospital, Goyang, Korea. gunil@duih.org
Abstract
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Mesenchymal stem cells (MSCs) exist in bone marrow and other musculoskeletal tissues. These cells contribute to the homeostasis of musculoskeletal tissue as well as support for the growth and differentiation of primitive hemopoietic cells. Recent advancements in tissue engineering and regeneratve medicine have brought MSCs to high attention as a potential source of cells which would differentiate to a variety of tissue, tailored to individual needs. In this review is briefly outlined the current status of MSCs, particularly focused on their biological characteristics and clinical applications.