J Korean Acad Periodontol.  2008 Aug;38(Suppl):363-372. 10.5051/jkape.2008.38.Suppl.363.

The histometric analysis of osseointegration in hydroxyapatite surface dental implants by ion beam-assisted deposition

• Kim MK
• Choi JY
• Chae GJ
• Jung UW
• Kim ST
• Lee IS
• Cho KS
• Kim CK
• Choi SH

• KMID: 1486871
• DOI: http://doi.org/10.5051/jkape.2008.38.Suppl.363

Abstract

PURPOSE
This study compared the effects of coating implants with hydroxyapatite (HA) using an ion beam-assisted deposition (IBAD) method prepared with machined, anodized, sandblasted and large-grit acid etched (SLA) surfaces in minipigs, and verified the excellency of coating method with HA using IBAD. MATERIAL AND METHODS: 4 male Minipigs(Prestige World Genetics, Korea), 18 to 24 months old and weighing approximately 35 to 40 kg, were chosen. All premolars and first molars of the maxilla were carefully extracted on each side. The implants were placed on the right side after an 8 week healing period. The implant stability was assessed by resonance frequency analysis (RFA) at the time of placement. 40 implants were divided into 5 groups; machined, anodized, anodized plus IBAD, SLA, and SLA plus IBAD surface implants. 4 weeks after implantation on the right side, the same surface implants were placed on the left side. After 4 weeks of healing, the minipigs were sacrificed and the implants were analyzed by RFA, histology and histometric.
RESULTS
RFA showed a mean implant stability quotient (ISQ) of 75.625+/-5.021, 76.125+/- 3.739 ISQ and 77.941+/-2.947 at placement, after 4 weeks healing and after 8 weeks, respectively. Histological analysis of the implants demonstrated newly formed, compact, mature cortical bone with a nearby marrow spaces. HA coating was not separated from the HA coated implant surfaces using IBAD. In particular, the SLA implants coated with HA using IBAD showed better contact osteogenesis. Statistical and histometric analysis showed no significant differences in the bone to implant contact and bone density among 5 tested surfaces.
CONCLUSION
We can conclude that rough surface implants coated with HA by IBAD are more biocompatible, and clinical, histological, and histometric analysis showed no differences when compared with the other established implant surfaces in normal bone.

Keyword

Ion beam-assisted deposition method; hydroxyapatite; rough surface implant; minipigs

MeSH Terms

Bicuspid
Bone Density
Bone Marrow
Dental Implants
Durapatite
Humans
Male
Maxilla
Molar
Osseointegration
Osteogenesis
Swine, Miniature
Dental Implants
Durapatite