J Korean Orthop Res Soc.  2010 Dec;13(2):88-94.

Effect of Traumatic Brain Injury on Healing of Femur shaft Fracture

Affiliations
  • 1Department of Orthopedic Surgery, Dankook University Hospital, Chon-an, Korea. osdku@dankook.ac.kr

Abstract

PURPOSE
Among the fracture patients, there is a tendency to form more callus and get fracture united earlier in groups with traumatic brain injury. This retrospective study is to evaluate the factors that might accelerate the bone formation by comparing two groups in serologic tests, clinical and radiologic results.
MATERIALS AND METHODS
From March 2001 to July 2009, femur shaft fracture patients were divided in two groups 1) without traumatic brain injury (32cases), 2) fracture with traumatic brain injury combined (30cases). We evaluated the routine serologic exams, amount of callus formations during the follow up period.
RESULTS
There was no statistical difference in WBC, CRP, total calcium, LDH level between two groups, except Alkaline phosphatase level. Amount of callus formation on AP radiograph at the last follow up period was 74.9% in study, 42.6% in control group. Lateral radiograph showed 73.2% of callus formation rate in study group and 32.0% in control group.
CONCLUSION
Two groups had no significant difference with the routine serologic exam except Alkaline phosphatase. Group with traumatic brain injury had much more amount of callus formation but there was no evidence of traumatic brain injury accelerate the fracture healing.

Keyword

Femur shaft; Traumatic brain injury; Brain; Callus formation; Callus; Alkaline phosphatase; fracture healing

MeSH Terms

Alkaline Phosphatase
Bony Callus
Brain
Brain Injuries
Calcium
Femur
Follow-Up Studies
Fracture Healing
Humans
Osteogenesis
Retrospective Studies
Serologic Tests
Alkaline Phosphatase
Calcium
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