Korean J Intern Med.  2011 Mar;26(1):94-98. 10.3904/kjim.2011.26.1.94.

Successful Treatment of Stereotactic Body Radiation Therapy Combined with Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Biliary Obstruction

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. baesh@catholic.ac.kr
  • 2Department of Radiation Oncology, The Catholic University of Korea School of Medicine, Seoul, Korea.
  • 3WHO Collaborating Center for Reference and Research on Viral Hepatitis, Seoul, Korea.

Abstract

Conventional radiation therapy (RT) is a widely recognized treatment for hepatocellular carcinoma (HCC). However, conventional RT plays only a limited role in HCC treatment because of its low efficacy and the low tolerance of the liver for this modality. Stereotactic body radiation therapy (SBRT) was recently developed and represents the most advanced radiation therapy technique currently available. It can deliver a high dose in a short time to well-defined hepatic tumors, with rapid dose fall-off gradients. We believe that SBRT with transarterial chemolipiodolization (TACL) may prove promising as a combined treatment modality for HCC due to its precision and relative safety. Here we present a case of successful treatment of advanced HCC with obstructive jaundice using this combined modality.

Keyword

Hepatocellular carcinoma; Stereotactic body radiation therapy; Transarterial chemolipiodolization; Obstructive jaundice

MeSH Terms

Carcinoma, Hepatocellular/complications/*therapy
*Chemoembolization, Therapeutic
Combined Modality Therapy
Humans
Jaundice, Obstructive/etiology/therapy
Liver Neoplasms/complications/*therapy
Male
Middle Aged
*Radiosurgery
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