- PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity
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Lee SJ, Lee JR, Hah HS, Kim YH, Ahn JH, Bae CD, Yang JM, Hahn MJ
- KMID: 756067
- Exp Mol Med.
- 2007 Aug;39(4):450-457.
Zinc finger protein 133 (ZNF133) is composed of a Kruppel-associated box (KRAB) domain and 14 contiguous zinc finger motifs. ZNF133 is regarded as a transcriptional repressor because the KRAB domain... -
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- Prognostic Value of TZAP Expression in Various Cancers: TCGA Data Analysis
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Park WJ, Heo YR, Lee JH
- KMID: 2437656
- Keimyung Med J.
- 2018 Jun;37(1):17-21.
- doi: 10.0000/kmj.2018.37.1.17
The zinc finger protein ZBTB48 is a telomere-associated factor and renamed it as telomeric zinc finger-associated protein (TZAP). It binds preferentially to long telomeres competing with TRF1 and TRF2. However,... -
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- Identification of Zinc Finger Genes that are Differentially Expressed upon Apoptosis of Ramos B Cells
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Shin MS, Kim SY, Dong SM, Na EY, Lee SH, Park WS, Lee JY, Yoo NJ
- KMID: 2275698
- Korean J Pathol.
- 1998 Dec;32(12):1043-1048.
Typical programmed cell death requires de novo macromolecular synthesis and shares common morphological changes referred to as apoptosis. To elucidate the molecular mechanism of apoptosis, we isolated 13 cDNA clones... -
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- A Comparative Genome-Wide Analysis of GATA Transcription Factors in Fungi
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Park J, Kim H, Kim S, Kong S, Park J, Kim S, Han HY, Park B, Jung K, Lee YH
- KMID: 2166236
- Genomics Inform.
- 2006 Dec;4(4):147-160.
GATA transcription factors are widespread eukaryotic regulators whose DNA-binding domain is a class IV zinc finger motif in the form CX(2)CX(17-20)CX(2)C followed by a basic region. In fungi, they act... -
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- Specific bovine antibody response against a new recombinant Cryptosporidium parvum antigen containing 4 zinc-finger motifs
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de Graaf D, de Coninck H, Petry F, Eeckhout I, Peeters JE
- KMID: 1384713
- Korean J Parasitol.
- 2002 Mar;40(1):59-64.
- doi: 10.3347/kjp.2002.40.1.59
A Cryptosporidium parvum sporozoite and oocyst lambda gt11 cDNA library was screened with a hyperimmune rabbit serum that was developed against insoluble fragments of ultrasonicated oocysts. A clone named... -
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- High Survivin and Low Zinc Finger of the Cerebellum 1 Expression Indicates Poor Prognosis in Triple-negative Breast Carcinoma
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Shi CT, Ma J, Shi QF, Zhang Y, Wang HN
- KMID: 2450119
- J Breast Cancer.
- 2019 Jun;22(2):248-259.
- doi: 10.4048/jbc.2019.22.e20
PURPOSE: Triple-negative breast carcinoma (TNBC) is accompanied with high risk of metastasis and recurrence. The present study aimed to explore the clinicopathological and prognostic roles of putative tumor-related genes in... -
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- Ritanserin, a 5HT2/1C receptor antagonist, does not block cocaine-induced behavioral alterations and zif268 mRNA expression in the striatum of the rats
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Choe ES, Kim JY
- KMID: 1580932
- Korean J Physiol Pharmacol.
- 2000 Oct;4(5):355-359.
Cocaine induces immediate early gene expression and behavioral changes by blocking dopamine transporters in the terminals of nigrostriatal neurons in the striatum. The pharmacological role of serotonin 2/1C (5HT2/1C) receptors in cocaine-induced expression... -
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- Fusion of the PLAG1 and CTNNB1 genes in pleomorphic adenoma of the salivary glands
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Kim JJ, Kim ES, Ko SO, Kim HB, Cho NP
- KMID: 2137007
- J Korean Assoc Oral Maxillofac Surg.
- 2003 Aug;29(4):206-211.
The pleomorphic adenoma is the most common neoplasm involving both the major and minor salivary glands. It is a benign, slowgrowing tumor, but local recurrences can occur. The pleomorphic adenoma... -
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- A case of Mowat-Wilson syndrome with developmental delays and Hirschsprung's disease
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Lee D, Kim JH, Cho JH, Oh MY, Lee BH, Kim GH, Choi JH, Yoo HW
- KMID: 2184498
- J Genet Med.
- 2014 Dec;11(2):79-82.
- doi: 10.5734/JGM.2014.11.2.79
Mowat-Wilson syndrome is an extremely rare genetic disease that is characterized by intellectual disability, facial dysmorphism, Hirschsprung's disease, and other congenital anomalies. This disorder is caused by heterozygous mutations or... -
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- Clinicopathologic and Prognostic Significance of the Zinc Finger of the Cerebellum Family in Invasive Breast Cancer
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Han W, Zhang C, Gao XJ, Wang HB, Chen F, Cao F, Hu YW, Ma J, Gu X, Ding HZ
- KMID: 2441868
- J Breast Cancer.
- 2018 Mar;21(1):51-61.
- doi: 10.4048/jbc.2018.21.1.51
PURPOSE: Five members of the zinc finger of the cerebellum (ZIC) family—ZIC1, ZIC2, ZIC3, ZIC4, and ZIC5—have been shown to be involved in various carcinomas. Here, we aimed to explore... -
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- Expression Pattern of KLF6 in Korean Gastric Cancers
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Cho YG, Kim CJ, Park CH, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS
- KMID: 2372768
- J Korean Gastric Cancer Assoc.
- 2005 Mar;5(1):34-39.
PURPOSE: KLF6, a member of the KLF family, is a ubiquitous zinc finger tumor suppressor protein that is mutated in several human cancers. Our aim was to determine whether the... -
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- Expression Pattern of KLF4 in Korean Gastric Cancers
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Song JH, Cho YG, Kim CJ, Park CH, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS
- KMID: 2372783
- J Korean Gastric Cancer Assoc.
- 2005 Sep;5(3):200-205.
PURPOSE: KLF4, a member of the KLF family, is a zinc finger tumor suppressor protein that is critical for gastric epithelial homeostasis. Our aim was to determine whether the altered... -
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- Lineage Differentiation Program of Invariant Natural Killer T Cells
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Kwon DI, Lee YJ
- KMID: 2400623
- Immune Netw.
- 2017 Dec;17(6):365-377.
- doi: 10.4110/in.2017.17.6.365
Invariant natural killer T (iNKT) cells are innate T cells restricted by CD1d molecules. They are positively selected in the thymic cortex and migrate to the medullary area, in which... -
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- Nerve growth factor(NGF) induces mRNA expression of the new transcription factor protein p48ZnF
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Heese K, Nagai Y, Sawada T
- KMID: 1380207
- Exp Mol Med.
- 2004 Apr;36(2):130-134.
Apoptosis, the cell's intrinsic death program, plays a crucial role in the regulation of tissue homeostasis, and abnormal inhibition of apoptosis is an indicator of cancer and autoimmune diseases, whereas... -
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- Evaluation of zinc finger E-box binding homeobox 1 and transforming growth factor-beta2 expression in bladder cancer tissue in comparison with healthy adjacent tissue
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Mahdavinezhad A, Yadegarazari R, Mousavi-Bahar SH, Poorolajal J, Jafari M, Amirzargar MA, Effatpanah H, Saidijam M
- KMID: 2368480
- Investig Clin Urol.
- 2017 Mar;58(2):140-145.
- doi: 10.4111/icu.2017.58.2.140
PURPOSE: The fifth most common cancer is allocated to bladder cancer (BC) worldwide. Understanding the molecular mechanisms of BC invasion and metastasis to identify target therapeutic strategies will improve disease... -
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- Decreases in Casz1 mRNA by an siRNA Complex Do not Alter Blood Pressure in Mice
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Ji SM, Shin YB, Park SY, Lee HJ, Oh B
- KMID: 2053283
- Genomics Inform.
- 2012 Mar;10(1):40-43.
- doi: 10.5808/GI.2012.10.1.40
Recent genomewide association studies of large samples have identified genes that are associated with blood pressure. The Global Blood Pressure Genetics (Global BPgen) and Cohorts for Heart and Aging Research... -
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- Identification of Differentially Expressed Genes Using RNA Fingerprinting in Cell after DNA Damage
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Lee JY, Shin MS, Dong SM, Na EY, Kim SY, Lee SH, Park WS, Yoo NJ
- KMID: 1725385
- Korean J Pathol.
- 1998 May;32(5):321-327.
RNA fingerprinting using on arbitrary primed polymerase chain reaction (RAP-PCR) was carried out to identify differentially expressed genes in HL-60 cell after treatment of methylmethane sulfonate (MMS). Twenty differentially expressed... -
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- IKKγ Facilitates the Activation of NF-κB by Hepatitis C Virus Core Protein
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Kang BY, Lee SY, Kim JI, Choi HJ, Joo WH, Kim DW
- KMID: 2421304
- J Bacteriol Virol.
- 2018 Sep;48(3):93-101.
- doi: 10.4167/jbv.2018.48.3.93
Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV core protein has been shown to modulate various cellular signaling pathways including the... -
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- CD24⺠Cell Depletion Permits Effective Enrichment of Thymic iNKT Cells While Preserving Their Subset Composition
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Park JY, Kwon J, Kim EY, Fink J, Kim HK, Park JH
- KMID: 2444162
- Immune Netw.
- 2019 Apr;19(2):e14.
- doi: 10.4110/in.2019.19.e14
Invariant NKT (iNKT) cells are a small subset of thymus-generated T cells that produce cytokines to control both innate and adaptive immunity. Because of their very low frequency in the... -
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- Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and alpha-synuclein aggregation
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Bae EJ, Yang NY, Lee C, Lee HJ, Kim S, Sardi SP, Lee SJ
- KMID: 2155418
- Exp Mol Med.
- 2015 Mar;47(3):e153.
- doi: 10.1038/emm.2014.128
Lysosomal dysfunction is a common pathological feature of neurodegenerative diseases. GTP-binding protein type A1 (GBA1) encodes beta-glucocerebrosidase 1 (GCase 1), a lysosomal hydrolase. Homozygous mutations in GBA1 cause Gaucher disease,... -
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