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The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy

Zhao W, He C, Jiang J, Zhao Z, Yuan H, Wang F, Shen B

Pyroptosis, a form of cell death associated with inflammation, is known to be involved in diabetic nephropathy (DN), and discoid domain receptor 1 (DDR1), an inflammatory regulatory protein, is reported...
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Hepatotoxic mechanism of diclofenac sodium on broiler chicken revealed by iTRAQ-based proteomics analysis

Sun C, Zhu T, Zhu Y, Li B, Zhang J, Liu Y, Juan C, Yang S, Zhao Z, Wan R, Lin S, Yin B

Background: At the therapeutic doses, diclofenac sodium (DFS) has few toxic side effects on mammals. On the other hand, DFS exhibits potent toxicity against birds and the mechanisms remain ambiguous. Objectives:...
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The Biocompatibility of Multi-Source Stem Cells and GelatinCarboxymethyl Chitosan-Sodium Alginate Hybrid Biomaterials

Wang X, Li S, Yu H, Lv J, Fan M, Wang X, Wang X, Liang Y, Mao L, Zhao Z

BACKGROUND: Nowadays, biological tissue engineering is a growing field of research. Biocompatibility is a key indicator for measuring tissue engineering biomaterials, which is of great significance for the replacement and...
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Atorvastatin regulates the migration and invasion of prostate cancer through the epithelial-mesenchymal transformation and matrix metalloproteinase pathways

Zhu Z, Cao Y, Liu L, Zhao Z, Yin H, Wang H

Purpose: Our purpose was to verify the effects of atorvastatin (ATO) on prostate cancer (PCa) proliferation, apoptosis, invasion, and metastasis and to further explore the drug’s mechanism of action. Materials and...
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The Application of Cartilage Tissue Engineering with Cell-Laden Hydrogel in Plastic Surgery: A Systematic Review

Wang G, Zhang X, Bu X, An Y, Bi H, Zhao Z

BACKGROUND: As a contour-supporting material, the cartilage has a significant application value in plastic surgery.Since the development of hydrogel scaffolds with sufficient biomechanical strength and high biocompatibility, cell-laden hydrogels have...
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Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome

Liu G, Li S, Chen N, Zhao Z, Guo M, Liu H, Feng J, Zhang D, Yao Z, Hu B

  • KMID: 2517537
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):426-435.
  • doi: 10.5056/jnm20134
Background/Aims Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disease characterized by recurrent abdominal pain and bowel dysfunction. However, the majority of previous neuroimaging studies focus on brain structure and...
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Distribution of Cadherin in the Parahippocampal Area of Developing Domestic Chicken Embryos

Zhou H, Wang X, Lin J, Zhao Z, Chang C

Hippocampal formation is important in spatial learning and memory. Members of the cadherin superfamily are observed in the neural system with diverse spatial and temporal expression patterns and are involved...
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Quantification of Fat Concentration and Vascular Response in Brown and White Adipose Tissue of Rats by Spectral CT Imaging

Peng XG, Zhao Z, Chang D, Bai Y, Xu Q, Ju S

OBJECTIVE: The purpose of the study was to non-invasively characterize and discriminate brown adipose tissue (BAT) from white adipose tissue (WAT) in rats using spectral computed tomography (CT) with histological...
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A Case of Alveolar Echinococcosis Occurring in the Hilar Bile Duct

Yang J, Zhao Z, Li S, Chen H

Echinococcosis is a disease caused by the Echinococcus species that parasitizes in humans. Alveolar echinococcosis (AE) which is caused by Echinococcus multilocularis is harmful to humans. AE mainly occurs in...
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Comparison of Monoexponential, Biexponential, Stretched-Exponential, and Kurtosis Models of Diffusion-Weighted Imaging in Differentiation of Renal Solid Masses

Zhang J, Suo S, Liu G, Zhang S, Zhao Z, Xu J, Wu G

OBJECTIVE: To compare various models of diffusion-weighted imaging including monoexponential apparent diffusion coefficient (ADC), biexponential (fast diffusion coefficient [Df], slow diffusion coefficient [Ds], and fraction of fast diffusion), stretched-exponential (distributed...
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Upregulation of PITX2 Promotes Letrozole Resistance Via Transcriptional Activation of IFITM1 Signaling in Breast Cancer Cells

Xu YY, Yu HR, Sun JY, Zhao Z, Li S, Zhang XF, Liao ZX, Cui MK, Li J, Li C, Zhang Q

PURPOSE: Although the interferon α (IFNα) signaling and the paired-like homeodomain transcription factor 2 (PITX2) have both been implicated in the progression of breast cancer (BCa), it remains obscure whether...
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Toward a Reconceptualization of Stem Cells from Cellular Plasticity

Liu T, Chen L, Zhao Z, Zhang S

The slow progress in clinical applications of stem cells and the bewildering mechanisms involved have puzzled many researchers. Recently, the increasing evidences have indicated that cells have superior plasticity in...
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Immune mechanisms in the different phases of acute tubular necrosis

Kundert F, Platen L, Iwakura T, Zhao Z, Marschner , Anders HJ

Acute kidney injury is a clinical syndrome that can be caused by numerous diseases including acute tubular necrosis (ATN). ATN evolves in several phases, all of which are accompanied by...
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Expression of DNA Damage Response Proteins and Associations with Clinicopathologic Characteristics in Chinese Familial Breast Cancer Patients with BRCA1/2 Mutations

Zhu X, Tian T, Ruan M, Rao J, Yang W, Cai X, Sun M, Qin G, Zhao Z, Wu J, Shao Z, Shui R, Hu Z

PURPOSE: The characteristic expression of DNA damage response proteins in familial breast cancers with BRCA1, BRCA2, or non-BRCA1/2 mutations has not been analyzed in Chinese patients. Our study aimed to...
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Prevalence of Plasmid-Mediated Quinolone Resistance Genes Among Escherichia coli in the Gut of Healthy People in Fuzhou, China

Li B, Chen Y, Wu Z, Zhao Z, Wu J, Cao Y

No abstract available.
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Use of autonomous maximal smile to evaluate dental and gingival exposure

Wang S, Lin H, Yang Y, Zhao X, Mei L, Zheng W, Li Y, Zhao Z

OBJECTIVE: This study was performed to validate the autonomous maximal smile (AMS) as a new reference for evaluating dental and gingival exposure. METHODS: Digital video clips of 100 volunteers showing posed...
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Tissue distribution of marbofloxacin in pigs after a single intramuscular injection

Yang F, Liu Y, Li Z, Wang Y, Liu B, Zhao Z, Zhou B, Wang G

Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the...
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Corrigendum: Correction of title spelling. Progressive changes in detrusor function and micturition patterns with chronic bladder ischemia

Zhao Z, Azad R, Yang JH, Siroky MB, Azadzoi KM

In the title of this paper, the spelling of "chronic" was unintentionally misprinted as "chroinc."
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Progressive changes in detrusor function and micturition patterns with chroinc bladder ischemia

Zhao Z, Azad R, Yang JH, Siroky MB, Azadzoi KM

PURPOSE: Lower urinary tract symptoms (LUTS) are bothersome constellation of voiding symptoms in men and women as they age. Multiple factors and comorbidities are attributed to this problem but underlying...
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IgG4-Associated Cholangitis Can Mimic Hilar Cholangiocarcinoma

Zaydfudim , Wang AY, de Lange E, Zhao Z, Moskaluk C, Bauer TW, Adams RB

IgG4-associated cholangitis can mimic hilar cholangiocarcinoma. Previously reported patients with IgG4-associated cholangitis mimicking cholangiocarcinoma had elevated serum IgG4 levels and long-segment biliary strictures. However, in the absence of other diagnostic...
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