- The potential renoprotection of xanthine oxidase inhibitors: Febuxostat versus allopurinol
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Ryu DR
- KMID: 2416089
- Kidney Res Clin Pract.
- 2017 Sep;36(3):207-208.
- doi: 10.23876/j.krcp.2017.36.3.207
No abstract available. -
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- Analysis of Relationship Between Spermatozoa Ability and Reactive Oxygen Species in Porcine: I. Sperm Preincubation by Xanthine and Xanthine Oxidase
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Park CK, Cheong HT, Kim JH, Lee SC, Yang BK, Kim CI
- KMID: 1930529
- Korean J Fertil Steril.
- 1998 Dec;25(3):315-322.
SUMMARY: The objective of this study was to test the effect of catalase on penetration in vitro by spermatozoa preincubated with xanthine and/or xanthine oxidase. The penetration rates were significantly... -
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- A Study on the Change of Xanthine Oxidase Activities in Experimental Cerebral Infarction
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Min BK, Park K, Kim YB, Hwang SN, Suk JS, Choi DY, Park YS, Lee YB
- KMID: 1691394
- J Korean Neurosurg Soc.
- 1992 Jul;21(7):813-825.
To observe the activity of the xanthine oxidase in cerebral ischemia, an ischemic model was made using a transorbital occlusion of the middle cerebral artery(MCA) in cats. Xanthine oxidase activity... -
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- A Case of Allopurinol Hypersensitivity Syndrome
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Jeon HJ, Bang HD, Kim KH, Kim KJ
- KMID: 2362394
- Ann Dermatol.
- 2003 Sep;15(3):107-109.
- doi: 10.5021/ad.2003.15.3.107
Allopurinol is a xanthine oxidase inhibitor widely used to control plasma uric acid levels. Serious and life threatening adverse effects such as the allopurinol hypersensitivity syndrome(AHS) are rare. We describe... -
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- Activities of Hepatic Antioxidant Enzymes in Bile Duct Ligates Rats
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Mun KC, Kwak CS
- KMID: 1891135
- Korean J Gastroenterol.
- 1997 Jul;30(1):66-71.
BACKGROUND AND AIMS: Protective role of antioxidant enzymes under the cholestasis was evaluated. METHODS:: The activity of xanthine oxidase, the amount of superoxide radical production, and the activities of antioxidant... -
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- Effect of Anti - inflammatory Drugs on the Degradation of Hyaluronate and Collagen by Reactive Oxygen Species
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Lee EW, Lee SH, Yim H, Lee KS, Chung MH
- KMID: 2446537
- J Korean Orthop Assoc.
- 1984 Oct;19(5):789-797.
- doi: 10.4055/jkoa.1984.19.5.789
Leukocytes, when subjected to phagocytic, immunologic or chemical stimuli, are known to exhibit a sequence of morphological and biochemical events which lead to the production of Hâ‚‚, Oâ‚‚, Oâ‚‚â», and... -
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- Effect of Allopurinol on Brain Infarction Following Middle Cerebral Artery Occlusion in Rats
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Chong YG, Chung HS, Suh JK, Lee HG, Lee KC, Chu JW
- KMID: 2187751
- J Korean Neurosurg Soc.
- 1990 Sep;19(8-9):1210-1220.
Of the many potential source of free radial generation, the enzyme xanthine oxidase has been shown to be important in ischemia in non-cerebral tissues. Oxygen-derived free radicals have been implicated... -
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- The variation of theophylline clearance with concurrent herb medication
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Jee YK, Kim YY, Cho SH, Min KU, Kim HS, Lee MH, Rheu YM
- KMID: 2046519
- Allergy.
- 1994 Sep;14(3):329-332.
Theophylline undergoes extensive metabo lism(above about 80% of total dose)and is also excreted as aparent drug through kid ney(below about 15% of total dose). The metabolism of theophylline involves hepatic... -
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- Change of Plasma Xanthine Oxidase Activity by Intermittent Hepatic Ischemia-Reperfusion
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Ha SJ, Kim JH, Park SS, Kim I, Baek W, Lim DG
- KMID: 2236673
- Korean J Anesthesiol.
- 2004 Nov;47(5):692-697.
- doi: 10.4097/kjae.2004.47.5.692
BACKGROUND: The pringle maneuver (PM), hepatic inflow occlusion, during hepatic surgery reduces intraoperative bleeding and blood transfusion requirement, but hepatic ischemia/reperfusion injury is inevitable. During ischemia, xanthine oxidoreductase is converted... -
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- Effects of Reactive Oxygen Species on Hyperactivation and Penetration Assay of Human Spermatozoa
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Jeon SS, Kim CM, Paick JS
- KMID: 1960309
- J Korean Androl Soc.
- 1997 Jun;15(1):29-38.
BACKGROUND: Our previous studies suggested that the reactive oxygen radical may be involved in hyperactivation of human sperm, in that superoxide anion promotes, and hydrogen peroxide inhibits, hyperactivation and acrosome... -
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- The Pathogenesis of the Brain Injury by the Xanthine Oxide and the Effect of Allopurinol on the Acute Focal Ischomia
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Shim KM, Choi KK
- KMID: 1965225
- Ewha Med J.
- 1990 Sep;13(3):157-164.
- doi: 10.12771/emj.1990.13.3.157
The purpose of this study was to demonstrate the effect of allopurinol on ischemia and reperfusion-induced cerebral injury and to investigate the importance of xanthine oxidase (XO)-linked free radical in... -
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- Xanthine Oxidase Stimulates the Enzyme Inactivation by Metal-Catalyzed Oxidation Systems
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Chay KO
- KMID: 2172399
- Chonnam Med J.
- 2001 Dec;37(4):357-365.
A cytosolic protein stimulating the inactivation of glutamine synthetase (GS) by metal-catalyzed oxidation (MCO) systems was purified and characterized from the rat lung. The protein was purified through the following... -
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- Effects of Renal Ischemia/Reperfusion on Renal Function in Rats
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Hwang YS, Park TC
- KMID: 1991365
- Korean J Urol.
- 1996 Jul;37(7):747-754.
Postischemic functional impairment of the kidney is a severe problem following living or cadeveric renal transplantation. It is well established that a substantial component of postischemic injury is caused by... -
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- Effects of Reactive Oxygen Species on Hyperactivation of Human Sperms
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Choo MS, PaicK JS, Park CW, Kim MS, Kim SW
- KMID: 1991364
- Korean J Urol.
- 1996 Jul;37(7):739-746.
capacitation of human sperm is essential for fertilization and is characterized visually by hyperactivated motility. There is a controversy whether reactive oxygen radicals cause infertility or stimulate sperm-zona interaction. We... -
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- Three Cases of Allopurinol-induced DRESS Syndrome
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Jeon EK, Lee KM, Kwon YB, Seo YJ, Park JK, Lee JH
- KMID: 2087389
- Korean J Dermatol.
- 2007 Jul;45(7):714-719.
Allopurinol (4-hydroxypyrazolo-[3,4-d]pyrimidine) is an effective and widely used xanthine oxidase inhibitor administered in the treatment of hyperuricemic states such as gout. Allopurinol-induced DRESS (Drug rash with eosinophilia and systemic symptoms)... -
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- Metabolism of Oxygen Free Radicals in the Regenerating Liver of Rats
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Park SK, Park HY, Mun KC, Kim YH, Kwak CS
- KMID: 1647121
- Korean J Gastroenterol.
- 2002 Oct;40(4):255-262.
BACKGROUND/AIMS: To know the metabolism of oxygen free radicals in the regenerating liver, the 70% (median and left lateral lobes) partial hepatectomy was performed in the Sprague-Dawley rats. METHODS: The original... -
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- A Study on the Role of Catecholamine in Reperfusion Damage of Ischemic Heart in Rat : Effect on Xanthine Oxidase Conversion
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Kim MS, Yoo HJ, Chung MH, Lim JK, Lee YS
- KMID: 1938102
- Korean Circ J.
- 1990 Sep;20(3):381-395.
- doi: 10.4070/kcj.1990.20.3.381
The present study was performed to investigate the role catecholamine in the genesis of reperfusion injury of ischemic heart. The possible involvement of catecholamine in the xanthine oxidase-linked production of... -
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- Elevated level of renal xanthine oxidase mRNA transcription after nephropathogenic infectious bronchitis virus infection in growing layers
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Lin H, Huang Q, Guo X, Liu P, Liu W, Zou Y, Zhu S, Deng G, Kuang J, Zhang C, Cao H, Hu G
- KMID: 2133624
- J Vet Sci.
- 2015 Dec;16(4):423-429.
- doi: 10.4142/jvs.2015.16.4.423
To assess relationships between xanthine oxidase (XOD) and nephropathogenic infectious bronchitis virus (NIBV) infection, 240 growing layers (35 days old) were randomly divided into two groups (infected and control) of... -
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- Reduction of Postischemic Cerebral Infarction and Cerebral Edema by Superoxide Dismutase and Allopurinol
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Oh WS, Park YK, Chong YK, Chung HS, Suh JK, Lee HK, Chu JW, Lee KC
- KMID: 2138516
- J Korean Neurosurg Soc.
- 1991 Apr;20(4):218-223.
The authors have inverstigated the hypothesis that ischemic injury could be attenuated by xanthine oxidase inhibitor(Allopurinol) and superoxide dismutase(SOD). This study used rat MAC model. Each animal was assigned to... -
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- Effect of Xanthine Oxidase Inhibitor on Cerebral Hypoxia-Ischemia in Neonatal Rats
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Choi DH, Oh YK, Park ST
- KMID: 1946172
- J Korean Pediatr Soc.
- 2002 Jun;45(6):732-742.
PURPOSE: In order to evaluate the hypoxia-ischemia(H-I) induced neurotoxicity and the protective effect of xanthine oxidase(XO) inhibitor(allopurinol), cell number, cell viability, lactate dehydrogenase(LDH), protein synthesis(PS) and protein kinase C(PKC) activity... -
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