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The potential renoprotection of xanthine oxidase inhibitors: Febuxostat versus allopurinol

Ryu DR

No abstract available.
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Analysis of Relationship Between Spermatozoa Ability and Reactive Oxygen Species in Porcine: I. Sperm Preincubation by Xanthine and Xanthine Oxidase

Park CK, Cheong HT, Kim JH, Lee SC, Yang BK, Kim CI

  • KMID: 1930529
  • Korean J Fertil Steril.
  • 1998 Dec;25(3):315-322.
SUMMARY: The objective of this study was to test the effect of catalase on penetration in vitro by spermatozoa preincubated with xanthine and/or xanthine oxidase. The penetration rates were significantly...
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A Study on the Change of Xanthine Oxidase Activities in Experimental Cerebral Infarction

Min BK, Park K, Kim YB, Hwang SN, Suk JS, Choi DY, Park YS, Lee YB

  • KMID: 1691394
  • J Korean Neurosurg Soc.
  • 1992 Jul;21(7):813-825.
To observe the activity of the xanthine oxidase in cerebral ischemia, an ischemic model was made using a transorbital occlusion of the middle cerebral artery(MCA) in cats. Xanthine oxidase activity...
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Effect of Anti - inflammatory Drugs on the Degradation of Hyaluronate and Collagen by Reactive Oxygen Species

Lee EW, Lee SH, Yim H, Lee KS, Chung MH

Leukocytes, when subjected to phagocytic, immunologic or chemical stimuli, are known to exhibit a sequence of morphological and biochemical events which lead to the production of H₂, O₂, O₂⁻, and...
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Relation between Gastroesophageal Reflux and Apnea in Preterm Infants

Ko JS, Kim JY, Park KR, Kim BI, Choi JH, Seo JK

  • KMID: 2304679
  • Korean J Gastroenterol.
  • 1998 Dec;32(6):733-739.
BACKGROUND/AIMS: In the preterm infants, gastroesophageal reflux (GER) has been associated with apnea. The aim of this study was to determine the effects of feeding, chest physiotherapy, and me chanical...
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A Case of Allopurinol Hypersensitivity Syndrome

Jeon HJ, Bang HD, Kim KH, Kim KJ

Allopurinol is a xanthine oxidase inhibitor widely used to control plasma uric acid levels. Serious and life threatening adverse effects such as the allopurinol hypersensitivity syndrome(AHS) are rare. We describe...
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Activities of Hepatic Antioxidant Enzymes in Bile Duct Ligates Rats

Mun KC, Kwak CS

  • KMID: 1891135
  • Korean J Gastroenterol.
  • 1997 Jul;30(1):66-71.
BACKGROUND AND AIMS: Protective role of antioxidant enzymes under the cholestasis was evaluated. METHODS:: The activity of xanthine oxidase, the amount of superoxide radical production, and the activities of antioxidant...
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Change of Plasma Xanthine Oxidase Activity by Intermittent Hepatic Ischemia-Reperfusion

Ha SJ, Kim JH, Park SS, Kim I, Baek W, Lim DG

BACKGROUND: The pringle maneuver (PM), hepatic inflow occlusion, during hepatic surgery reduces intraoperative bleeding and blood transfusion requirement, but hepatic ischemia/reperfusion injury is inevitable. During ischemia, xanthine oxidoreductase is converted...
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Effect of Allopurinol on Brain Infarction Following Middle Cerebral Artery Occlusion in Rats

Chong YG, Chung HS, Suh JK, Lee HG, Lee KC, Chu JW

  • KMID: 2187751
  • J Korean Neurosurg Soc.
  • 1990 Sep;19(8-9):1210-1220.
Of the many potential source of free radial generation, the enzyme xanthine oxidase has been shown to be important in ischemia in non-cerebral tissues. Oxygen-derived free radicals have been implicated...
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Effects of Reactive Oxygen Species on Hyperactivation and Penetration Assay of Human Spermatozoa

Jeon SS, Kim CM, Paick JS

  • KMID: 1960309
  • J Korean Androl Soc.
  • 1997 Jun;15(1):29-38.
BACKGROUND: Our previous studies suggested that the reactive oxygen radical may be involved in hyperactivation of human sperm, in that superoxide anion promotes, and hydrogen peroxide inhibits, hyperactivation and acrosome...
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The Pathogenesis of the Brain Injury by the Xanthine Oxide and the Effect of Allopurinol on the Acute Focal Ischomia

Shim KM, Choi KK

The purpose of this study was to demonstrate the effect of allopurinol on ischemia and reperfusion-induced cerebral injury and to investigate the importance of xanthine oxidase (XO)-linked free radical in...
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The variation of theophylline clearance with concurrent herb medication

Jee YK, Kim YY, Cho SH, Min KU, Kim HS, Lee MH, Rheu YM

  • KMID: 2046519
  • Allergy.
  • 1994 Sep;14(3):329-332.
Theophylline undergoes extensive metabo lism(above about 80% of total dose)and is also excreted as aparent drug through kid ney(below about 15% of total dose). The metabolism of theophylline involves hepatic...
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Xanthine Oxidase Stimulates the Enzyme Inactivation by Metal-Catalyzed Oxidation Systems

Chay KO

  • KMID: 2172399
  • Chonnam Med J.
  • 2001 Dec;37(4):357-365.
A cytosolic protein stimulating the inactivation of glutamine synthetase (GS) by metal-catalyzed oxidation (MCO) systems was purified and characterized from the rat lung. The protein was purified through the following...
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A Study of Human Melanocytes Culture

Lee KH, Lee MH, Park JK, Haw CR

  • KMID: 2038914
  • Korean J Dermatol.
  • 1990 Apr;28(2):136-146.
The author evaluated the optimal concentration of 3 compositions of TIC medium which has used as the melanacytes culture medium. The concentrations of placental extract and bovine pituitary extract, which...
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Antioxidant effects of serotonin and L-DOPA on oxidative damages of brain synaptosomes

Ham SS, Kim DH, Lee SH, Kim YS, Lee CS

  • KMID: 1554130
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):147-155.
Antioxidant effects of serotonin and L-DOPA on neuronal tissues were examined by studying the oxidative damages of brain synaptosomal components. The study further explored the mechanism by which they exert protective actions. Serotonin...
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Modulation by aspartate of ischemia/reperfusion-induced oxidative stress in rat liver

Park YC, Oh SI, Park YH, Park SC

  • KMID: 2128621
  • Exp Mol Med.
  • 1997 Mar;29(1):19-23.
Ischemia-reperfusion injury is related with oxygen free radicals; a reason which has been suggested for this is the conversion of xanthine dehydrogenase (XDH) into xanthine oxidase (XO). In the present...
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Elevated level of renal xanthine oxidase mRNA transcription after nephropathogenic infectious bronchitis virus infection in growing layers

Lin H, Huang Q, Guo X, Liu P, Liu W, Zou Y, Zhu S, Deng G, Kuang J, Zhang C, Cao H, Hu G

To assess relationships between xanthine oxidase (XOD) and nephropathogenic infectious bronchitis virus (NIBV) infection, 240 growing layers (35 days old) were randomly divided into two groups (infected and control) of...
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Effects of Renal Ischemia/Reperfusion on Renal Function in Rats

Hwang YS, Park TC

  • KMID: 1991365
  • Korean J Urol.
  • 1996 Jul;37(7):747-754.
Postischemic functional impairment of the kidney is a severe problem following living or cadeveric renal transplantation. It is well established that a substantial component of postischemic injury is caused by...
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A Study on the Role of Catecholamine in Reperfusion Damage of Ischemic Heart in Rat : Effect on Xanthine Oxidase Conversion

Kim MS, Yoo HJ, Chung MH, Lim JK, Lee YS

The present study was performed to investigate the role catecholamine in the genesis of reperfusion injury of ischemic heart. The possible involvement of catecholamine in the xanthine oxidase-linked production of...
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Effect of Xanthine Oxidase Inhibitor on Cerebral Hypoxia-Ischemia in Neonatal Rats

Choi DH, Oh YK, Park ST

  • KMID: 1946172
  • J Korean Pediatr Soc.
  • 2002 Jun;45(6):732-742.
PURPOSE: In order to evaluate the hypoxia-ischemia(H-I) induced neurotoxicity and the protective effect of xanthine oxidase(XO) inhibitor(allopurinol), cell number, cell viability, lactate dehydrogenase(LDH), protein synthesis(PS) and protein kinase C(PKC) activity...
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