- The Effects of Wnt Protein on Proliferation and Stemness Maintenance of Corneal Limbal Stem Cells (CLSCs)
-
Jin HJ, Joo CK
- KMID: 2212261
- J Korean Ophthalmol Soc.
- 2009 Apr;50(4):588-593.
- doi: 10.3341/jkos.2009.50.4.588
PURPOSE: To evaluate the effects of the Wnt protein on proliferation and stemness maintenance of cultured corneal limbal stem cells. METHODS: We examined the expression of Wnt proteins by Western blot... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Wnt-1 on the Growth and Apoptosis of FRTL-5 Cells
-
Kim JM, Kim TY, Shong YK, Rhee YS, Park EJ, Choi HC, Kim WB
- KMID: 2178240
- J Korean Endocr Soc.
- 2007 Feb;22(1):35-44.
- doi: 10.3803/jkes.2007.22.1.35
BACKGROUND: Wnt proteins are major signaling molecules involved in embryonic induction, generation of cell polarity and the cell fate decision. A central player in the Wnt signaling pathways is beta-catenin.... -
- CITED
-
- Close
- SHARE
-
- Close
- Insulin-Like Growth Factor 1 Actions in Developing Brain and the Interaction with Wnt Pathway
-
Lee SY
- KMID: 1434737
- Ann Pediatr Endocrinol Metab.
- 2012 Mar;17(1):10-15.
- doi: 10.6065/apem.2012.17.1.10
Insulin like growth factor (IGF)-1 signaling through type 1 IGF receptor (IGF1R) is essential to the normal growth and development of the central nervous system. IGF-1 stimulates proliferation of neural... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
-
Kikuchi A, Kishida S, Yamamoto H
- KMID: 1105271
- Exp Mol Med.
- 2006 Feb;38(1):1-10.
The Wnt signaling pathway is conserved in various species from worms to mammals, and plays important roles in cellular proliferation, differentiation, and migration. Wnt stabilizes cytoplasmic beta-catenin and then the... -
- CITED
-
- Close
- SHARE
-
- Close
- Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
-
Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH
- KMID: 1009391
- Exp Mol Med.
- 2009 Oct;41(10):695-706.
- doi: 10.3858/emm.2009.41.10.076
Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and... -
- CITED
-
- Close
- SHARE
-
- Close
- The Wnt/beta-catenin signaling pathway regulates the development of airway remodeling in patients with asthma
-
Kwak HJ, Park DW, Seo JY, Moon JY, Kim TH, Sohn JW, Shin DH, Yoon HJ, Park SS, Kim SH
- KMID: 2359885
- Exp Mol Med.
- 2015 Dec;47(12):e198.
- doi: 10.1038/emm.2015.91
Airway remodeling is a key characteristic of chronic asthma, particularly in patients with a fixed airflow limitation. The mechanisms underlying airway remodeling are poorly understood, and no therapeutic option is... -
- CITED
-
- Close
- SHARE
-
- Close
- Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils
-
Jung YS, Lee HY, Kim SD, Park JS, Kim JK, Suh PG, Bae YS
- KMID: 2154246
- Exp Mol Med.
- 2013 Jun;45(6):e27.
Wnt5a is a ligand that activates the noncanonical Wnt signaling pathways (beta-catenin-independent pathways). Human neutrophils expressed several Wnt5a receptors, such as Frizzled 2, 5 and 8. Stimulation of human neutrophils... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Significance of Aberrant Wnt7a Promoter Methylation in Human Non-Small Cell Lung Cancer in Koreans
-
Kim TH, Moon JY, Kim SH, Paik SS, Yoon HJ, Shin DH, Park SS, Sohn JW
- KMID: 2129645
- J Korean Med Sci.
- 2015 Feb;30(2):155-161.
- doi: 10.3346/jkms.2015.30.2.155
The Wnt signaling pathway has regulatory roles in cell proliferation, differentiation, and polarity. Aberrant Wnt pathway regulation can lead to abnormal cell proliferation and cancer, and loss of Wnt7a expression... -
- CITED
-
- Close
- SHARE
-
- Close
- Transcriptional profiling and Wnt signaling activation in proliferation of human hepatic stellate cells induced by PDGF-BB
-
Shin H, Park SY, Lee KB, Shin E, Nam SW, Lee JY, Jang JJ
- KMID: 1384056
- Korean J Hepatol.
- 2009 Dec;15(4):486-495.
- doi: 10.3350/kjhep.2009.15.4.486
BACKGROUND/AIMS: This study aimed to better understand gene expression profiles of human hepatic stellate cell (HSC) activation and the relationship with the Wnt signaling pathway. METHODS: The global transcript levels... -
- CITED
-
- Close
- SHARE
-
- Close
- Wnt7a Deficiency Could Predict Worse Disease-Free and Overall Survival in Estrogen Receptor-Positive Breast Cancer
-
Yi K, Min KW, Wi YC, Kim Y, Shin SJ, Chung MS, Jang K, Paik SS
- KMID: 2398206
- J Breast Cancer.
- 2017 Dec;20(4):361-367.
- doi: 10.4048/jbc.2017.20.4.361
PURPOSE: Wnt7a is a glycoprotein involved in embryonic development and the progression of different types of malignant tumors. This study aimed to detect the level of Wnt7a expression in breast... -
- CITED
-
- Close
- SHARE
-
- Close
- Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
-
Park BM, Kim EJ, Nam HJ, Zhang D, Bae CH, Kang M, Kim H, Lee W, Bogen B, Lim SK
- KMID: 2419106
- Yonsei Med J.
- 2017 May;58(3):505-513.
- doi: 10.3349/ymj.2017.58.3.505
PURPOSE: Dickkopf 1 (DKK1) has been extensively investigated in mouse models of multiple myeloma, which results in osteolytic bone lesions. Elevated DKK1 levels in bone marrow plasma and serum inhibit... -
- CITED
-
- Close
- SHARE
-
- Close
- Current Status of Molecular Targeted Therapies in Hepatocellular Carcinoma
-
Suh SJ, Yim HJ
- KMID: 1501636
- Korean J Gastroenterol.
- 2013 Mar;61(3):136-146.
- doi: 10.4166/kjg.2013.61.3.136
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death in Korea. Curative treatment is only possible when the disease is diagnosed at the early stage. The prognosis... -
- CITED
-
- Close
- SHARE
-
- Close
- Static magnetic fields promote osteoblastic/cementoblastic differentiation in osteoblasts, cementoblasts, and periodontal ligament cells
-
Kim EC, Park J, Kwon IK, Lee SW, Park SJ, Ahn SJ
- KMID: 2392716
- J Periodontal Implant Sci.
- 2017 Oct;47(5):273-291.
- doi: 10.5051/jpis.2017.47.5.273
PURPOSE: Although static magnetic fields (SMFs) have been used in dental prostheses and osseointegrated implants, their biological effects on osteoblastic and cementoblastic differentiation in cells involved in periodontal regeneration remain... -
- CITED
-
- Close
- SHARE
-
- Close
