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The Effect of High-Dose Valsartan on Left Ventricular Function Following Primary Percutaneous Coronary Intervention

Park TH

No abstract available.
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Sacubitril/Valsartan in Asian Patients with Heart Failure with Reduced Ejection Fraction

Dewan P, Docherty K, McMurray J

The Prospective comparison of Angiotensin Receptor-neprilysin inhibitor (ARNI) with Angiotensin converting enzyme inhibitor (ACEI) to Determine Impact on Global Mortality and morbidity in Heart Failure (HF) trial (PARADIGM-HF) showed that...
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Issues on carcinogen contaminated antihypertensive drugs and constructing drug safety management system

Park BJ

European Medicines Agency withdrew valsartan from European market in July 2018 because it was contaminated with carcinogen, N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA). Medicines and Healthcare Products Regulatory Agency also found...
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Pharmacokinetic and Pharmacodynamic Study Determines Factors Affecting Blood Pressure Response to Valsartan

Cho JM, Yim SV, Jin H, Sohn IS, Hwang HJ, Park CB, Jin ES, Kim CJ

  • KMID: 2330957
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):88-96.
BACKGROUND: Valsartan is an angiotensin II receptor blocker and is used for patient with hypertension. Although response to valsartan varies each individual, there is no study about factors affecting the...
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Telmisartan Versus Valsartan in Patients With Hypertension: Effects on Cardiovascular, Metabolic, and Inflammatory Parameters

Lim SY, Kim SW, Kim EJ, Kang JH, Kim SA, Kim YK, Na JO, Choi CU, Lim HE, Han SW, Rha SW, Park CG, Seo HS, Oh DJ

BACKGROUND AND OBJECTIVES: Angiotensin-receptor blockers (ARBs) have beneficial effects on cardiovascular, metabolic, and inflammatory parameters in addition to controlling blood pressure (BP). However, few comparative clinical studies have been conducted...
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Evaluation of Cardiac Function by Transthoracic Echocardiography in Subjects with ST-Segment Elevation Myocardial Infarction Following Primary Percutaneous Coronary Intervention according to Valsartan Dose: The Valsartan One Center Trial

Kim SS, Jeon HK, Cho GM, Lee JH, Kim SJ, Park MY, Lee SJ, Shim BJ, Lee DH, Shin WS, Lee JM, Youn HJ

BACKGROUND: The aim of this study was to evaluate the mid-term changes in cardiac function by transthoracic echocardiogram (TTE) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous...
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Effects of Telmisartan Compared with Valsartan on Plasma Adiponectin Levels and Arterial Stiffness in Patients with Type 2 Diabetes: A Pilot Study

Park SY, Kim SG, Park J, Lee YJ, Kim HY, Seo JA, Kim NH, Choi KM, Baik SH, Choi DS

BACKGROUND: Telmisartan, used for the treatment of hypertension, has been shown to function as a partial agonist of peroxime proliferative activated receptor-nu (PPAR-nu). Theoretically, telmisartan which simultaneously blocks the angiotensin...
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The Effect of an Angiotensin Receptor Blocker on Arterial Stiffness in Type 2 Diabetes Mellitus Patients with Hypertension

Kim JH, Oh SJ, Lee JM, Hong EG, Yu JM, Han KA, Min KW, Son HS, Chang SA

BACKGROUND: Hypertension and type 2 diabetes mellitus are major risk factors for cardiovascular disease. This study analyzed the changes in central aortic waveforms and pulse wave velocity as well as...
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Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study

Kim HJ, Han SJ, Kim DJ, Jang HC, Lim S, Choi SH, Kim YH, Shin DH, Kim SH, Kim TH, Ahn YB, Ko SH, Kim NH, Seo JA, Kim HY, Lee KW

BACKGROUND/AIMS: Oxidative stress plays an important role in the pathogenesis and progression of diabetic complications and antagonists of renin-angiotensin system and amlodipine have been reported previously to reduce oxidative stress....
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24-Hour blood pressure response to lower dose (30 mg) fimasartan in Korean patients with mild to moderate essential hypertension

Lee HY, Kim CH, Song JK, Chae SC, Jeong MH, Kim DS, Oh BH

BACKGROUND/AIMS: Fimasartan is an angiotensin type 1 receptor blocker (ARB) which has comparable efficacy and tolerability with other ARBs. The aim of this study was to evaluate 24-hour blood pressure...
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Telmisartan-induced sprue-like enteropathy: a case report and a review of patients using non-olmesartan angiotensin receptor blockers

Mandavdhare HS, Sharma V, Prasad KK, Kumar A, Rathi M, Rana SS

Recent studies have identified sprue-like illness associated with the use of the antihypertensive agent olmesartan medoxomil. However, whether this condition is specific to the use of olmesartan or is associated...
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The Comparative Clinical Effects of Valsartan and Ramipril in Patients With Heart Failure

Lee KH, Jeong MH, Ahn YK, Lee WS, Jung DH, Cho JG, Park JC, Kang JC, Oh SK, Kim NH, Yun KH, Yoo NJ, Moon Y, Rhew JY, Lim JH, Jeon SH, Park OY, Lee SU, Kang DG

BACKGROUND AND OBJECTIVES: Angiotensin II receptor blocker (ARB) has emerged as an alternative to angiotensin converting enzyme inhibitor (ACEI) for the treatment of heart failure. This study aimed at comparing...
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Effect of low-dose valsartan on proteinuria in normotensive immunoglobulin A nephropathy with minimal proteinuria: a randomized trial

Jo YI, Na HY, Moon JY, Han SW, Yang DH, Lee SH, Park HC, Choi HY, Lim SD, Kie JH, Lee YK, Shin SK

BACKGROUND/AIMS: Immunoglobulin A nephropathy (IgAN) is a generally progressive disease, even in patients with favorable prognostic features. In this study, we aimed to investigate the antiproteinuric effect and tolerability of...
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Additive Beneficial Effects of Valsartan Combined with Rosuvastatin in the Treatment of Hypercholesterolemic Hypertensive Patients

Jang JY, Lee SH, Kim BS, Seo HS, Kim WS, Ahn Y, Lee NH, Koh KK, Kang TS, Jo SH, Hong BK, Bae JH, Yang HM, Cha KS, Kim BS, Kwak CH, Cho DK, Kim U, Zo JH, Kang DH, Pyun WB, Chun KJ, Namgung J, Cha TJ, Juhn JH, Jung Y, Jang Y

BACKGROUND AND OBJECTIVES: We compared the efficacy and safety of valsartan and rosuvastatin combination therapy with each treatment alone in hypercholesterolemic hypertensive patients. SUBJECTS AND METHODS: Patients who met inclusion criteria...
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Effect of Valsartan on Blood Pressure and Urinary Albumin Excretion in Hypertensive Type 2 Diabetic Patients: An Open-Label, Multicenter Study

Park SJ, Kim DJ, Kim HJ, Park SY, Seo JA, Kim NH, Choi SH, Lim S, Jang HC, Ko SH, Song KH, Ahn YB, Kim SK, Cho YW, Kang JG, Ihm SH, Park CY, Park SW, Shin DH, Kim YH, Lee KW

BACKGROUND: Activation of renin-angiotensin system (RAS) has been an important mechanism of microvascular and macrovascular complications in diabetic patients. It has been reported that RAS blockades reduce the development and...
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Effect of Valsartan on N-Terminal Pro-Brain Natriuretic Peptide in Patient With Stable Chronic Heart Failure: Comparison With Enalapril

Lee YS, Kim KS, Lee JB, Ryu JK, Choi JY, Kim BK, Chang SG, Hur SH, Lee BR, Jung BC, Hong GR, Kim BS, Park TH, Kim YD, Kim TI, Kim DS

BACKGROUND AND OBJECTIVES: The plasma concentration of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is a st-rong prognostic indicator for patients with heart failure (HF) across all stages of the condition. Several...
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Effects of Local Pancreatic Renin-Angiotensin System on the Microcirculation of Rat with Severe Acute Pancreatitis

Pan Z, Feng L, Long H, Wang H, Feng J, Chen F

Severe acute pancreatitis (SAP) is normally related to multiorgan dysfunction and local complications. Studies have found that local pancreatic renin-angiotensin system (RAS) was significantly upregulated in drug-induced SAP. The present...
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Effects of Valsartan on Carotid Arterial Stiffness in Patients with Newly Diagnosed Hypertension: A Comparative Study with Global Arterial Stiffness

Yim YR, Kim KH, Cho JY, Yoon HJ, Hong YJ, Park HW, Kim JH, Ahn Y, Jeong MH, Cho JG, Park JC

BACKGROUND: To compare the parameters of local carotid stiffness with those of global arterial stiffness and to investigate the effects of angiotensin II receptor blocker (ARB) on the parameters of...
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Operative Treatment of Intertrochanteric Fractures of the Femur in Elderly Patiene

Park SW, Hahn SB

  • KMID: 2310505
  • J Korean Fract Soc.
  • 1995 Apr;8(2):332-339.
There are many problems in the treatment of the intertrochanteric fractures due to oslteoporosis and unstable pattern of fractures in elderly patients and determined by quality of the bone, geometry...
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Lateral Condyle Fracture of Tibia Treated by Open Reduction and Internal Fixation

Sohn JM, Chang JH, An DH, Park SA

  • KMID: 2310275
  • J Korean Fract Soc.
  • 1996 Jan;9(1):137-145.
Tibial condyle fracture involving articular surface can produce some disabilities of the knee because they are usually accompanied with the injuries of the ligaments and menisci. Though recent studies suggest...
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