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Effects of Valproic Acid on the Survival of Human Tennon's Capsule Fibroblasts

Lee SE, Kim JW

PURPOSE: To investigate the effects of valproic acid on the survival of cultured human Tenon's capsule fibroblasts (HTFBs). METHODS: Primary cultured HTFBs were exposed to 0, 0.25, 0.5, and 1.0 mM...
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A Case of Valproic Acid Overdose Treated with Continuous Veno-Venous Hemodiafiltration: A Case Report

Choi SC, Ahn JH, Jung YS, Min YG

Valproic acid intoxication is a fairly common clinical problem that can result in serious complications. Traditionally the treatment of valproic acid overdose has been limited to supportive measures, but high...
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A Case of Valproic Acid Associated with Acute Pancreatitis

Lee EH, Yi YJ, Park HJ

  • KMID: 2177015
  • J Korean Child Neurol Soc.
  • 2005 May;13(1):69-73.
Valproic acid is a commonly prescribed medication approved for epilepsy, migraine and bipolar disorder. The common adverse effects associated with valproic acid include nausea, vomiting, tremor and weight gain. Less...
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Valproic Acid-Induced Hyperammonemic Encephalopathy Initially Misdiagnosed as Nonconvulsive Status Epilepticus

Ko JA, Seo IK, Park HJ, Lee TK, Park SA, Cho YS

  • KMID: 1818932
  • J Korean Soc Emerg Med.
  • 2011 Aug;22(4):382-386.
Valproic acid-induced hyperammonemic encephalopathy (VHE) is a very rare but serious complication. Discontinuation of valproic acid is the first and critical step for treatment. VHE can occur in people with...
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Valproate Is Contraindicated in POLG1 Mutations

Finsterer

No abstract available.
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A case of valproic acid-induced hyperammonemic encephalopathy with normal liver function

Choi JH, Kim JE, Lee KS, Heo C, Nam TK, Kim JW, Park SW

  • KMID: 2258720
  • Korean J Med.
  • 2008 Dec;75(6):680-684.
Valproic acid is an effective anticonvulsant used in neurology and psychiatry. Valproic acid-induced hyperammonemic encephalopathy is an unusual complication characterized by a decreasing level of consciousness, the development of progressive...
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A Case of Valproic Acid Induced DRESS Syndrome

Kim YH, Choi CW, Lee GY, Kim WS

  • KMID: 2247515
  • Korean J Dermatol.
  • 2012 Jan;50(1):85-88.
DRESS syndrome is an uncommon but potentially life-threatening subset of severe drug eruption characterized by fever, rash, leukocytosis with eosinophilia or atypical lymphocytosis, lymphadenopathy, and liver or renal dysfunction. The...
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The Effect of Valproic Acid on Ovary of Pubertal Child

Moon EK, Lim HK, Yoo JH, Lee KS

  • KMID: 2137165
  • J Korean Child Neurol Soc.
  • 2001 May;9(1):86-94.
PURPOSE: Valproic acid is effective and safe in adults and children for the treatment of a variety of seizure types. But, according to the recent reports, this drug induce hyperandrogenism,...
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Study for the hepatotoxicity in mice with long-term administration of valproate

Lee KH

  • KMID: 1684830
  • J Korean Child Neurol Soc.
  • 1993 Sep;1(1):24-32.
No abstract available.
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Effect of Valproic Acid on Nitric Oxide and Nitric Oxide Synthase in Trabecular Meshwork Cell

Son MS, Park CH, Kim JW

PURPOSE: To investigate the effects of valproic acid on the production of nitric oxide (NO) and expression of endothelial nitric oxide synthase (eNOS) in cultured human trabecular meshwork cells (HTMC). METHODS:...
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Two Cases of Stevens-Johnson Syndrome Related to Concomitant Use of Lamotrigine and Valproic Acid

Kim JW, Kim KS

  • KMID: 2302509
  • Korean J Dermatol.
  • 2005 Aug;43(8):1105-1109.
Lamotrigine (LTG) is a relatively safe and new antiepiletic drug which is effective for bipolar depression and partial or generalized seizures. However, administration of LTG in combination with valproic acid...
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A Case of Drug Rash with Eosinophilia and Systemic Symptoms Associated with Valproic Acid and Olanzapine Treatment in Patient with Bipolar Disorder

Lee U, Lim SW

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening, medication-induced hypersensitivity reaction with long latency. It is characterized by fever, rash, leukocytosis with eosinophilia, atypical lymphocytosis,...
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The Recurrence of Seizure due to Decreased Valproic Acid Level after Administration of Carbapenem

Kim DG, Kim OJ

  • KMID: 1510308
  • J Korean Epilepsy Soc.
  • 2007 Jun;11(1):64-66.
Valproic acid (VPA) is one of the most commonly used antiepileptic drug, but has many drug-drug interactions. A 58-year-old male under the vegetative state has been well controlled with valproic...
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Curly Hair Induced by Valproate in Bipolar Disorder

Yasemin G

No abstract available.
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Comparative Add-on Trial of Vigabatrin and Valproic Acid on Intractable Partial Seizures with Carbamazepine Monotherapy

Lee SK, Nam HW, Chang IJ

  • KMID: 2016243
  • J Korean Neurol Assoc.
  • 1997 Aug;15(4):754-761.
PURPOSE: To evaluate the efficacy of vigabatrin and valproic acid add-on therapy in the treatment of uncontrolled partial-onset seizures through randomized active controlled parallel-group trial. METHODS: Criteria for entry included...
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A life-threatening case of acute valproic acid overdose treated successfully with serial hemoperfusion and hemodialysis

Park JH, Park JS, Park MY, Joo HS, Yang JO, Lee EY, Hong SY

  • KMID: 2306014
  • Korean J Med.
  • 2004 Oct;67(4):404-408.
Valproic acid is available as an antiepileptic therapy and has been used treat bipolar disorder and migraine headaches. In the setting of accidental or intentional ingestion of valproic acid overdose,...
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Valproate Induced Hair Loss and Curly Hair in Bipolar Disorder

Uygur OF, Uygur H

No abstract available.
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Valproic Acid-Induced Hyperammonemic Encephalopathy as a Cause of Neurologic Deterioration after Unruptured Aneurysm Surgery

Lee S, Cheong J, Kim C, Kim JM

Neurological deficits after brain surgery are not uncommon, and correct and prompt differential diagnosis is essential to initiate appropriate treatment. We describe a patient suffering from loss of consciousness due...
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A Case of Epilepsia Arithmetices

Byun YJ, Jung C, Park MY, Park CS

  • KMID: 1686136
  • J Korean Neurol Assoc.
  • 1992 Mar;10(1):113-118.
Activation of epileptic seizure or electroencephalographic epileptiform discharges by mental calculation is rare, not reported in Korea. We report a 10-year-old right handed school girl without previous seizure history who...
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Erythema Nodosum Associated with Valproate

Woo YR, Koo DW, Jung KE, Lee JS

No abstract available.
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