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Clinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study

Imamura K, Yao K, Nimura S, Kanemitsu T, Miyaoka M, Ono Y, Ueki T, Tanabe H

Background/Aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC. Methods: This single-center...
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White Opaque Substance, a New Optical Marker on Magnifying Endoscopy: Usefulness in Diagnosing Colorectal Epithelial Neoplasms

Yamasaki K, Hisabe T, Yao K, Ishihara H, Imamura K, Yasaka T, Tanabe H, Iwashita A, Ueki T

Background/Aims: A white substance that is opaque to endoscopic light is sometimes observed in the epithelium during narrowband imaging with magnifying endoscopy of gastric or colorectal epithelial neoplasms. This prospective...
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Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancer

Ono Y, Yao K, Takaki Y, Ishikawa S, Imamura K, Koga A, Ohtsu K, Kanemitsu T, Miyaoka M, Hisabe T, Ueki T, Ota A, Tanabe H, Haraoka S, Nimura S, Iwashita A, Sato S, Wakasaki R

Background/Aims: Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous...
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Association between occurrence of multiple white and flat elevated gastric lesions and oral proton pump inhibitor intake

Hasegawa R, Yao K, Kanemitsu T, Arima H, Hirase T, Hiratsuka Y, Takeda K, Imamura K, Ohtsu K, Ono Y, Miyaoka M, Hisabe T, Ueki T, Tanabe H, Ohta A, Nimura S

Background/Aims: Multiple white and flat elevated lesions (MWFL) that develop from the gastric corpus to the fornix may be strongly associated with oral antacid intake. Therefore, this study aimed to...
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Histological Architecture of Gastric Epithelial Neoplasias That Showed Absent Microsurface Patterns, Visualized by Magnifying Endoscopy with Narrow-Band Imaging

Chuman K, Yao K, Kanemitsu T, Nagahama T, Miyaoka M, Takahashi H, Imamura K, Hasegawa R, Ueki T, Tanabe H, Haraoka S, Iwashita A

Background/Aims: The objective of this study was to elucidate the histological structure of the absent microsurface patterns (MSPs) that were visualized by magnifying endoscopy with narrow-band imaging (M-NBI). Methods: The study...
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Magnified Endoscopic Findings of Multiple White Flat Lesions: A New Subtype of Gastric Hyperplastic Polyps in the Stomach

Hasegawa R, Yao K, Ihara S, Miyaoka M, Kanemitsu , Chuman K, Ikezono G, Hirano A, Ueki T, Tanabe H, Ota A, Haraoka S, Iwashita A

BACKGROUND/AIMS:: While the occurrence of multiple whitish flat elevated lesions (MWFL) was first reported in 2007, no studies on MWFL have been published to date. The present retrospective observational study...
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Risk factors for severity of colonic diverticular hemorrhage

Kinjo K, Matsui T, Hisabe T, Ishihara H, Kojima T, Chuman K, Yasukawa S, Beppu T, Koga A, Ishikawa S, Kishi M, Takatsu N, Hirai F, Yao K, Ueki T, Washio M

BACKGROUND/AIMS: Colonic diverticular hemorrhage (DH) was a rare disease until the 1990s, and its incidence has increased rapidly since 2000 in Japan. In recent years, colonic DH has been the...
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