- Mini-review; Melamine-related Urinary Stone Disease
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Kang HG
- KMID: 2197124
- J Korean Soc Pediatr Nephrol.
- 2009 Apr;13(1):21-25.
Last year, an epidemic of infantile urinary stone disease developed in China. Investigation revealed that melamine-tainted diary product caused urinary stone in these infants. Young infants were susceptible to the... -
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- A case of antiepileptic drug hypersensitivity syndrome by lamotrigine mimicking infectious mononucleosis and atypical Kawasaki disease
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Yoo SJ, Park IS, Suh ES
- KMID: 2281121
- Korean J Pediatr.
- 2009 Mar;52(3):389-391.
- doi: 10.3345/kjp.2009.52.3.389
Antiepileptic drug hypersensitivity syndrome (AHS), a delayed immunological reaction, is a relatively rare side effect of antiepileptic drugs and is usually overlooked. An array of symptoms can occur one to... -
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- Predictive Factors for Valproate Treatment in Childhood Absence Epilepsy
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Chi GH, Hwang TG
- KMID: 2329440
- J Korean Child Neurol Soc.
- 2010 May;18(1):7-13.
PURPOSE: To determine the clinical and demographic factors associated with long-term remission of valproate(VPA) therapy in childhood absence epilepsy. METHODS: Fifty-six cases of childhood and juvenile absence epilepsy were identified by... -
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- Rhabdomyolysis after Lamotrigine Poisoning: A Case report
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Kim GB, Gu HD
- KMID: 2203446
- J Korean Soc Clin Toxicol.
- 2008 Dec;6(2):142-145.
Lamotrigine is a newer anti-epileptic drug for adjunctive treatment of refractory epilepsy, partial seizures, generalized tonic-clonic seizures, and bipolar disorder. Lamotrigine overdose causes serious central nervous and cardiovascular problems, but... -
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- Treatment Strategy for Non-Responders to PDE5 Inhibitors
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Park NC, Kim TN, Park HJ
- KMID: 2320852
- World J Mens Health.
- 2013 Apr;31(1):31-35.
Currently, phosphodiesterase type 5 (PDE5) inhibitors are the initial treatment option for erectile dysfunction. The reported efficacy of PDE5 inhibitors is about 70%, although it is significantly lower in difficult-to-treat... -
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- A Study of Antidepressant and Mood Stabilizer's Effect on Phase of Peripheral Circadian Rhythm in Rat Fibroblast
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Koh SH, Noh JS
- KMID: 1856477
- Korean J Psychopharmacol.
- 2011 Jan;22(1):23-28.
OBJECTIVE: Circadian rhythm is cyclic variations in biological activity, which is crucial for physiology in mammals and alterations in circadian rhythm may be related to mood disorders. However, the effect... -
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- Occupational Risk Factors for Prostate Cancer: A Meta-analysis
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Krstev S, Knutsson A
- KMID: 2454669
- J Cancer Prev.
- 2019 Jun;24(2):91-111.
- doi: 10.15430/JCP.2019.24.2.91
Prostate cancer is the second most common cancer in men worldwide. There are many occupational factors that have been suggested to cause prostate cancer. Our aim was to evaluate the... -
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- Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
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Im SG, Yoo SH, Park YM, Lee SJ, Jang SK, Jeon DO, Cho HJ, Oh MJ
- KMID: 2164369
- Clin Mol Hepatol.
- 2015 Jun;21(2):180-182.
- doi: 10.3350/cmh.2015.21.2.180
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs.... -
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- Past, Present and Future of PDE5 Inhibitor
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Kim JJ, Moon DG
- KMID: 2226569
- Korean J Androl.
- 2008 Jun;26(2):49-60.
The phosphodiesterase type-5 inhibitors (PDE5-Is) sildenafil, vardenafil and tadalafil are widely used as first-line therapy for erectile dysfunction (ED). Since the approval of sildenafil in 1998, more than 40 million... -
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- Target Therapy for Hepatocellular Carcinoma
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Yoon SK
- KMID: 2168205
- Hanyang Med Rev.
- 2012 May;32(2):118-125.
- doi: 10.7599/hmr.2012.32.2.118
Hepatocellular carcinoma (HCC) is a highly malignant tumor that has limited treatment options in its advanced state. The efficacy of current anti-cancer chemotherapy in advanced HCC has not been satisfactory,... -
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- The pharmacological management of neuropathic pain
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Ko Y, Kim YH
- KMID: 2015657
- J Korean Med Assoc.
- 2012 Jun;55(6):582-592.
- doi: 10.5124/jkma.2012.55.6.582
Neuropathic pain has recently been defined as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system". Neuropathic pain is a debilitating chronic condition that... -
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- Intrathecal lamotrigine blocks and reverses antinociceptive morphine tolerance in rats
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Jun IG, Park JY, Choi YS, Kim TH
- KMID: 2092202
- Korean J Anesthesiol.
- 2009 Jun;56(6):687-692.
- doi: 10.4097/kjae.2009.56.6.687
BACKGROUND: Chronic administration of morphine leads to the development of tolerance. We investigated the effects of intrathecal lamotrigine on the spinal morphine tolerance in rats that are undergoing tail flick... -
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- New antiepileptic drugs. II. Clinical use
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Lee BI
- KMID: 1123812
- J Korean Med Sci.
- 1996 Aug;11(4):289-304.
- doi: 10.3346/jkms.1996.11.4.289
No abstract available. -
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- The Effects of Antiepileptic Drugs on Balance in Older People
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Lee GH
- KMID: 2185061
- J Korean Neurol Assoc.
- 2008 Aug;26(3):186-193.
BACKGROUND: The purpose of this study was to quantitatively assess the subclinical balance dysfunction in elderly people taking antiepileptic drugs. METHODS: We recruited sixty-three patients who were at least 50 years... -
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- The Clinical Analysis of Paroxysmal Kinesigenic Dyskinesia
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Suh J, Moon HH, Kwon S
- KMID: 1441215
- J Korean Child Neurol Soc.
- 2012 Jun;20(2):57-63.
PURPOSE: Paroxysmal kinesigenic dyskinesia (PKD) is one of the movement disorders in which dyskinesia occurs in a part of the body by a sudden movement after a rest under a... -
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- Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats
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Jun IG, Kim SH, Yoon YI, Park JY
- KMID: 1429208
- J Korean Med Sci.
- 2013 Feb;28(2):300-307.
- doi: 10.3346/jkms.2013.28.2.300
Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This... -
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- An Open, Randomized, Multicenter Comparative Clinical Trial of Lamotrigine and Carbamazepine as Initial Monotherapy in Previously Untreated Epilepsies
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Korean Lamotrigine Study Group
- KMID: 2181929
- J Korean Epilepsy Soc.
- 2008 Jun;12(1):27-34.
PURPOSE: To evaluate the efficacy and safety of lamotrigine compared to carbamazepine as the initial drug for previously untreated epilepsies. METHODS: Previously untreated epileptic patients were randomly allocated into the lamotrigine... -
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- Effect of Antiepileptic Drugs on Fetal Congenital Malformation and Cognitive Function
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Lee SJ
- KMID: 2343364
- J Korean Neurol Assoc.
- 2010 Nov;28(4):249-256.
Although the majority of women with epilepsy give birth to healthy children, intrauterine exposure to antiepileptic drugs (AEDs) increases the risk of fetal major congenital malformations (MCMs), a two-to threefold... -
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- Synergistic effect of melamine in combination with cyanuric acid on urinary tract toxicity in rats
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Lee IC, Kim SH, Baek HS, Kang SS, Kim JC
- KMID: 2055100
- J Biomed Res.
- 2013 Sep;14(3):145-153.
The present study investigated the urinary tract toxicity of melamine alone or in combination with cyanuric acid in rats. Male rats were orally administered melamine alone (800 mg/kg) or melamine... -
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- Bone Mineral Density in Ambulatory Epileptic Children with New Antiepileptic Drug Monotherapy
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Ko JH, Lee GM, Lee EH, Chung S
- KMID: 2329481
- J Korean Child Neurol Soc.
- 2011 Dec;19(3):184-190.
PURPOSE: This study was conducted for evaluation of the effects of new antiepileptic drugs on bone mineral density in children with epilepsy. METHODS: The study group consisted of 35 age and... -
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