- Do Toll-like Receptors Play a New Role as a Biomarker of Irritable Bowel Syndrome?
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Kim HJ
- KMID: 2422841
- J Neurogastroenterol Motil.
- 2018 Oct;24(4):510-511.
- doi: 10.5056/jnm18153
No abstract available. -
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- Bacterial 23S Ribosomal RNA, a Ligand for Toll-like Receptor 13
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Manzoor Z, Koh YS
- KMID: 2168672
- J Bacteriol Virol.
- 2012 Dec;42(4):357-358.
- doi: 10.4167/jbv.2012.42.4.357
Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition... -
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- Nucleic Acid Recognition and Signaling by Toll-like Receptor 9: Compartment-dependent Regulation
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Koh YS
- KMID: 2168631
- J Bacteriol Virol.
- 2011 Jun;41(2):131-132.
- doi: 10.4167/jbv.2011.41.2.131
Toll-like receptor 9 binds to DNA from bacteria or viruses and activates a signaling pathway that leads to the induction of proinflammatory cytokines and type I interferon. Adaptor complex AP-3... -
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- The role of CD14 and Toll-like receptors on the release of MMP-8 in the LPS recognition pathway
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Yang SM, Kim TI, Seol YJ, Lee YM, Ku Y, Chung CP, Han SB, Rhyu IC
- KMID: 2424988
- J Korean Acad Periodontol.
- 2006 Sep;36(3):579-590.
No abstract available. -
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- The Gate Way of Communication between Microorganism and Human Body: Toll-like Receptors
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Park JY, Han DS
- KMID: 1647232
- Korean J Gastroenterol.
- 2002 Nov;40(5):287-293.
Innate immunity is the first line of defense against invading microorganisms and does not require the memory or lymphocytic clonal expansion. Toll-like receptors (TLRs) play an important role in this... -
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- Innate Immunity and Toll Like Receptors
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Kim KH
- KMID: 2140971
- Korean J Pediatr.
- 2004 Jan;47(1):6-11.
The innate immune system is essential for host defense and is responsible for early detection of pathogenic microorganisms. Whereas the structure of microbial compounds has been extensively studied, the molecular... -
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- Helper T Cell Polarizing Through Dendritic Cells
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Han M
- KMID: 2279595
- Korean J Pediatr.
- 2005 Jan;48(1):6-12.
In the last few years, a spectrum of dendritic cells(DCs), including toll like receptors(TLRs), might play a critical role in regulating allergy and asthma. DC plays a central role in... -
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- Toll-Like Receptors and Kidney Diseases
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Noh JW
- KMID: 2307150
- Korean J Nephrol.
- 2011 Jan;30(1):4-17.
Toll-like receptors (TLRs) are pattern-recognition receptors which identify pathogens or microorganisms associated molecular patterns (PAMP or MAMP) at the very early stage of their invasion to the host. So TLRs... -
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- Clinical Significance of Toll-Like Receptor and Toll-Like Receptor Blocker
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Choi JY, Song PH, Ko YH
- KMID: 2319421
- Urogenit Tract Infect.
- 2016 Apr;11(1):1-6.
- doi: 10.14777/uti.2016.11.1.1
The mammalian Toll-like receptor (TLR) family, consisting of 13 members, plays an important role in innate recognition of specific patterns of microbial products. TLR-dependent recognition subsequently causes an activation of... -
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- Neonatal innate immunity and Toll-like receptor
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Yoon HS
- KMID: 1455872
- Korean J Pediatr.
- 2010 Dec;53(12):985-988.
- doi: 10.3345/kjp.2010.53.12.985
The innate immune response is the first line of defense against microbial infections. Innate immunity is made up of the surface barrier, cellular immunity and humoral immunity. In newborn, immunologic... -
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- The Innate Immune Responses in Pathogenesis of Chronic Rhinosinusitis
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Mo JH
- KMID: 2146667
- J Rhinol.
- 2014 May;21(1):22-27.
- doi: 10.0000/jr.2014.21.1.22
Chronic rhinosinusitis (CRS) is a multifactorial and heterogeneous disease, and variousfactors, such as inflammation, infection, fungus, and superantigens, have been proposed to play crucial roles in its pathogenesis. Recently, the... -
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- Dendritic Cell Functions in Allergen Recognition and Response
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Han M
- KMID: 2314366
- Pediatr Allergy Respir Dis.
- 2005 Jun;15(2):87-97.
Dendritic cells (DCs) are crucial in the defense against pathogens and allergen. The ability of allergens to cause allergic inflammation is contingent upon the presence of microenvironment that either privileges... -
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- Systematic Analysis of Translocator Protein 18 kDa (TSPO) Ligands on Toll-like Receptors-mediated Pro-inflammatory Responses in Microglia and Astrocytes
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Lee JW, Nam H, Yu SW
- KMID: 2354879
- Exp Neurobiol.
- 2016 Oct;25(5):262-268.
- doi: 10.5607/en.2016.25.5.262
Translocator protein 18 kDa (TSPO) is a mitochondrial protein highly expressed on reactive microglia and astrocytes, and is considered as a biomarker for neurodegeneration and brain damage, especially neuroinflammation. Toll-like... -
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- Autophagy as an Innate Immune Modulator
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Oh JE, Lee HK
- KMID: 2150764
- Immune Netw.
- 2013 Feb;13(1):1-9.
- doi: 10.4110/in.2013.13.1.1
Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which... -
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- Lipopolysaccharide: Basic Biochemistry, Intracellular Signaling, and Physiological Impacts in the Gut
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Rhee SH
- KMID: 2284892
- Intest Res.
- 2014 Apr;12(2):90-95.
- doi: 10.5217/ir.2014.12.2.90
Lipopolysaccharide (LPS), a main constituent of Gram-negative bacterial membrane, specifically activates Toll-like receptor 4, leading to the production of pleiotropic cytokines/chemokines which in turn regulate inflammatory and innate and subsequent... -
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- Cloning of Danio rerio toll-like receptor 1
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Choi HY
- KMID: 2036973
- Korean Lepr Bull.
- 2005 Dec;38(2):3-14.
Toll-like receptors (TLRs) play a central role of innate immunity as well as of enhancing the adaptive immunity. TLR1 interacts with TLR2 to recognize the mycobacterial 19-kD lipoprotein. Danio rerio... -
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- Toll-like Receptors and Innate Immunity
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Yuk JM, Jo EK
- KMID: 2168650
- J Bacteriol Virol.
- 2011 Dec;41(4):225-235.
- doi: 10.4167/jbv.2011.41.4.225
Toll-like receptors (TLRs) are the best-characterized membrane-bound receptors in innate immune cells, including macrophages and dendritic cells. Upon recognition of specific ligands originating from pathogen- and modified self-derived molecules, TLRs... -
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- Toll-like Receptors and NOD-like Receptors in Innate Immune Defense during Pathogenic Infection
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Jin HS, Park JK, Jo EK
- KMID: 1726971
- J Bacteriol Virol.
- 2014 Sep;44(3):215-225.
- doi: 10.4167/jbv.2014.44.3.215
In response to invading pathogens, the body immune system develops an immediate defense mechanism, i.e., innate immune response, which is detected in almost all living organisms including mammals, plants, insects,... -
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- Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
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Krishnan J, Choi S
- KMID: 1806244
- Genomics Inform.
- 2012 Sep;10(3):153-166.
- doi: 10.5808/GI.2012.10.3.153
A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. Such receptors include Toll-like receptors (TLRs), which recognize various patterns of... -
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- Toll-Like Receptor Ligands as Cancer Immunotherapeutics
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Lee SE, Rhee JH
- KMID: 1434755
- J Bacteriol Virol.
- 2012 Sep;42(3):255-262.
- doi: 10.4167/jbv.2012.42.3.255
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in a wide spectrum of cell types that recognize distinctive ligands and subsequently activate adaptive immune responses. TLR ligands are considered... -
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