- Nanotechnology Biomimetic Cartilage Regenerative Scaffolds
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Lim EH, Sardinha J, Myers S
- KMID: 2120868
- Arch Plast Surg.
- 2014 May;41(3):231-240.
- doi: 10.5999/aps.2014.41.3.231
Cartilage has a limited regenerative capacity. Faced with the clinical challenge of reconstruction of cartilage defects, the field of cartilage engineering has evolved. This article reviews current concepts and strategies... -
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- In situ tissue regeneration through host stem cell recruitment
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Ko IK, Lee SJ, Atala A, Yoo JJ
- KMID: 2154276
- Exp Mol Med.
- 2013 Nov;45(11):e57.
The field of tissue engineering has made steady progress in translating various tissue applications. Although the classical tissue engineering strategy, which involves the use of culture-expanded cells and scaffolds to... -
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- The principles of tissue engineering and its recent advances and future prospects
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Kim WS
- KMID: 2342367
- J Korean Med Assoc.
- 2014 Feb;57(2):145-154.
The definition of tissue engineering by Langer is "an interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain,... -
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- Toward angiogenesis of implanted bio-artificial liver using scaffolds with type I collagen and adipose tissue-derived stem cells
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Lee JG, Bak SY, Nahm JH, Lee SW, Min SO, Kim KS
- KMID: 2243049
- Korean J Hepatobiliary Pancreat Surg.
- 2015 May;19(2):47-58.
- doi: 10.14701/kjhbps.2015.19.2.47
BACKGROUNDS/AIMS: Stem cell therapies for liver disease are being studied by many researchers worldwide, but scientific evidence to demonstrate the endocrinologic effects of implanted cells is insufficient, and it is... -
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- Periodontal regeneration with nano-hyroxyapatite-coated silk scaffolds in dogs
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Yang C, Lee JS, Jung UW, Seo YK, Park JK, Choi SH
- KMID: 2329652
- J Periodontal Implant Sci.
- 2013 Dec;43(6):315-322.
PURPOSE: In this study, we investigated the effect of silk scaffolds on one-wall periodontal intrabony defects. We conjugated nano-hydroxyapatite (nHA) onto a silk scaffold and then seeded periodontal ligament cells... -
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- Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct
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Lim EH, Sardinha J, Myers S, Stevens M
- KMID: 2167853
- Arch Plast Surg.
- 2013 Nov;40(6):676-686.
- doi: 10.5999/aps.2013.40.6.676
BACKGROUND: To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation... -
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- State-of-the-Art Strategies for the Vascularization of Three-Dimensional Engineered Organs
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Min S, Ko IK, Yoo JJ
- KMID: 2455137
- Vasc Spec Int.
- 2019 Jun;35(2):77-89.
- doi: 10.5758/vsi.2019.35.2.77
Engineering three-dimensional (3D) implantable tissue constructs is a promising strategy for replacing damaged or diseased tissues and organs with functional replacements. However, the efficient vascularization of new 3D organs is... -
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- Meniscal Transplants and Scaffolds: A Systematic Review of the Literature
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Dangelmajer S, Familiari , Simonetta , Kaymakoglu M, Huri G
- KMID: 2371527
- Knee Surg Relat Res.
- 2017 Mar;29(1):3-10.
- doi: 10.5792/ksrr.16.059
The reported incidence of meniscal tears is approximately 61 per 100,000. In instances where preservation of the native meniscus is no longer a feasible option, meniscal allograft transplantation (MAT) and... -
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- Development of Artificial Substitutes for Upper Digestive Tract: Personal Experience of Trials and Errors
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Chung EJ
- KMID: 2469951
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Dec;62(12):675-680.
- doi: 10.3342/kjorl-hns.2019.00710
The current treatments for esophageal diseases, such as carcinomas, trauma or congenital malformations, require surgical intervention, and esophageal reconstruction using redundant parts of the gastrointestinal tract. However, the use of... -
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- Periodontal tissue reaction to customized nano-hydroxyapatite block scaffold in one-wall intrabony defect: a histologic study in dogs
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Lee JS, Park WY, Cha JK, Jung UW, Kim CS, Lee YK, Choi SH
- KMID: 2027787
- J Periodontal Implant Sci.
- 2012 Apr;42(2):50-58.
- doi: 10.5051/jpis.2012.42.2.50
PURPOSE: This study evaluated histologically the tissue responses to and the effects of a customized nano-hydroxyapatite (n-HA) block bone graft on periodontal regeneration in a one-wall periodontal-defect model. METHODS: A customized... -
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- Hybrid Additive Microfabrication Scaffold Incorporated with Highly Aligned Nanofibers for Musculoskeletal Tissues
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Sooriyaarachchi D, Minière H, Maharubin , Tan GZ
- KMID: 2441253
- Tissue Eng Regen Med.
- 2019 Feb;16(1):29-38.
- doi: 10.1007/s13770-018-0169-z
BACKGROUND: Latest tissue engineering strategies for musculoskeletal tissues regeneration focus on creating a biomimetic microenvironment closely resembling the natural topology of extracellular matrix. This paper presents a novel musculoskeletal tissue... -
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- Effects of combined mechanical stimulation on the proliferation and differentiation of pre-osteoblasts
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Kang KS, Lee SJ, Lee H, Moon W, Cho DW
- KMID: 1107378
- Exp Mol Med.
- 2011 Jun;43(6):367-373.
- doi: 10.3858/emm.2011.43.6.040
We observed how combined mechanical stimuli affect the proliferation and differentiation of pre-osteoblasts. For this research, a bioreactor system was developed that can simultaneously stimulate cells with cyclic strain and... -
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- Porous Polyurethane Scaffold as a Tracheal Prosthesis Material
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Kim HS, Chung SM, Jung SY, Kim SJ, Kim KY
- KMID: 2277309
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2012 Jan;55(1):30-36.
- doi: 10.3342/kjorl-hns.2012.55.1.30
BACKGROUND AND OBJECTIVES: The purpose of this study was to confirm the usefulness of the porous polyurethane scaffold as a tracheal prosthesis for repair of partial tracheal defect. SUBJECTS AND METHOD:... -
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- 3D Printing Technology and Its Applications for Tissue/Organ Regeneration
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Ahn CB, Son KH, Lee JW
- KMID: 2202603
- J Korean Soc Transplant.
- 2015 Dec;29(4):187-193.
- doi: 10.4285/jkstn.2015.29.4.187
Three-dimensional (3D) printing, also known as additive manufacturing (AM), has been used frequently in regenerative or translational medicine. In addition, recent advances in 3D printing technologies have opened the door... -
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- Evaluation of a canine small intestinal submucosal xenograft and polypropylene mesh as bioscaffolds in an abdominal full-thickness resection model of growing rats
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Lee AJ, Lee SH, Chung WH, Kim DH, Chung DJ, Do SH, Kim HY
- KMID: 1705519
- J Vet Sci.
- 2013 Jun;14(2):175-184.
- doi: 10.4142/jvs.2013.14.2.175
We evaluated the biological scaffold properties of canine small intestinal submucosa (SIS) compared to a those of polypropylene mesh in growing rats with full-thickness abdominal defects. SIS is used to... -
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- Assessment of stem cell viability in the initial healing period in rabbits with a cranial bone defect according to the type and form of scaffold
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Kang SH, Park JB, Kim I, Lee W, Kim H
- KMID: 2455803
- J Periodontal Implant Sci.
- 2019 Aug;49(4):258-267.
- doi: 10.5051/jpis.2019.49.4.258
PURPOSE: Increased bone regeneration has been achieved through the use of stem cells in combination with graft material. However, the survival of transplanted stem cells remains a major concern. The... -
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- The effect of silk fibroin and rhBMP-2 on bone regeneration in rat calvarial defect model
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Nam JH, Noh KL, Pang EO, Yu WG, Kang ES, Kweon HY, Kim SG, Park YJ
- KMID: 2328501
- J Korean Assoc Oral Maxillofac Surg.
- 2010 Oct;36(5):366-374.
INTRODUCTION: This study evaluated the capability of silk fibroin (SF) and recombinant human bone morphogenetic protein-2 loaded SF (SF-BMP) as a bone defect replacement matrix when grafted in a calvarial... -
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- Transplantation of Mesenchymal Stem Cells for Acute Spinal Cord Injury in Rats: Comparative Study between Intralesional Injection and Scaffold Based Transplantation
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Kim YC, Kim YH, Kim JW, Ha KY
- KMID: 2468268
- J Korean Med Sci.
- 2016 Sep;31(9):1373-1382.
- doi: 10.3346/jkms.2016.31.9.1373
Experimental stem cell therapy for spinal cord injury (SCI) has been extensively investigated. The selection of effective cell transplantation route is also an important issue. Although various types of scaffold... -
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- Fibroblasts in three dimensional matrices: cell migration and matrix remodeling
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Rhee S
- KMID: 1099862
- Exp Mol Med.
- 2009 Dec;41(12):858-865.
- doi: 10.3858/emm.2009.41.12.096
Fibroblast-collagen matrix culture has facilitated the analysis of cell physiology under conditions that more closely resemble an in vivo-like environment compared to conventional 2-dimensional (2D) cell culture. Furthermore, it has... -
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- Treatment of Osteochondritis Dissecans of the Knee with Autologous Iliac Bone Graft and Hyaluronic Acid Scaffold
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Hinzpeter , Zamorano A, Barahona M, Campos P
- KMID: 2451850
- Knee Surg Relat Res.
- 2019 Jun;31(2):143-146.
- doi: 10.5792/ksrr.18.053
Osteochondritis dissecans (OCD) is a condition that corresponds to an idiopathic focal lesion affecting the subchondral bone with possible compromise of the stability of the adjacent cartilage. Treatment depends on... -
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