J Korean Med Assoc.  2014 Feb;57(2):145-154.

The principles of tissue engineering and its recent advances and future prospects

Affiliations
  • 1Department of Plastic Surgery, Chung-Ang University College of Medicine, Seoul, Korea. kimws@cau.ac.kr

Abstract

The definition of tissue engineering by Langer is "an interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function." This technology has achieved remarkable growth in the past 20 years, provoked by its potential role in regenerating new tissues and naturally healing injured or diseased organs. Although stem cells are still in the research phase, their pluripotency and unlimited capacity for self-renewal may enable significant advances for reconstructive and cosmetic procedures with this engineering technology. This article aims at outlining the principles of tissue engineering and its recent advances and future prospects.

Keyword

Engineering; Tissue; Regenerative Medicine; Stem Cells; Tissue Scaffolds; Reconstructive Surgical Procedures

MeSH Terms

Biological Science Disciplines
Reconstructive Surgical Procedures
Regenerative Medicine
Stem Cells
Tissue Engineering*
Tissue Scaffolds

Reference

1. Rhie JW. Adipose-derived stem cells: characterization and clinical application. J Korean Med Assoc. 2012; 55:757–769.
Article
2. Lee JH, Lee KH, Kim MH, Kim JP, Lee SJ, Yoon J. Possibility of undifferentiated human thigh adipose stem cells differentiating into functional hepatocytes. Arch Plast Surg. 2012; 39:593–599.
Article
3. Rodeheffer MS, Birsoy K, Friedman JM. Identification of white adipocyte progenitor cells in vivo. Cell. 2008; 135:240–249.
Article
4. Kocher AA, Schuster MD, Szabolcs MJ, Takuma S, Burkhoff D, Wang J, Homma S, Edwards NM, Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med. 2001; 7:430–436.
Article
5. Aziz Aly LA, Menoufy HE, Ragae A, Rashed LA, Sabry D. Adipose stem cells as alternatives for bone marrow mesenchymal stem cells in oral ulcer healing. Int J Stem Cells. 2012; 5:104–114.
Article
6. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131:861–872.
Article
7. Kang HJ, Kim JY, Lee HJ, Kim KH, Kim TY, Lee CS, Lee HC, Park TH, Kim HS, Park YB. Magnetic bionanoparticle enhances homing of endothelial progenitor cells in mouse hindlimb ischemia. Korean Circ J. 2012; 42:390–396.
Article
8. Discher DE, Janmey P, Wang YL. Tissue cells feel and respond to the stiffness of their substrate. Science. 2005; 310:1139–1143.
Article
9. Castner DG, Ratner BD. Biomedical surface science: foundations to frontiers. Surf Sci. 2002; 500:28–60.
Article
10. Hoffman AS. Hydrogels for biomedical applications. Adv Drug Deliv Rev. 2002; 54:3–12.
Article
11. Boudou T, Crouzier T, Ren K, Blin G, Picart C. Multiple functionalities of polyelectrolyte multilayer films: new biomedical applications. Adv Mater. 2010; 22:441–467.
Article
12. Hollister SJ. Scaffold design and manufacturing: from concept to clinic. Adv Mater. 2009; 21:3330–3342.
Article
13. Cao Y, Mitchell G, Messina A, Price L, Thompson E, Penington A, Morrison W, O'Connor A, Stevens G, Cooper-White J. The influence of architecture on degradation and tissue ingrowth into three-dimensional poly(lactic-co-glycolic acid) scaffolds in vitro and in vivo. Biomaterials. 2006; 27:2854–2864.
Article
14. Norotte C, Marga FS, Niklason LE, Forgacs G. Scaffold-free vascular tissue engineering using bioprinting. Biomaterials. 2009; 30:5910–5917.
Article
15. Vashi AV, Abberton KM, Thomas GP, Morrison WA, O'Connor AJ, Cooper-White JJ, Thompson EW. Adipose tissue engineering based on the controlled release of fibroblast growth factor-2 in a collagen matrix. Tissue Eng. 2006; 12:3035–3043.
Article
16. Folkman J, Hochberg M. Self-regulation of growth in three dimensions. J Exp Med. 1973; 138:745–753.
Article
17. Demarchez M, Hartmann DJ, Prunieras M. An immunohistological study of the revascularization process in human skin transplanted onto the nude mouse. Transplantation. 1987; 43:896–903.
Article
18. Khouri RK, Schlenz I, Murphy BJ, Baker TJ. Nonsurgical breast enlargement using an external soft-tissue expansion system. Plast Reconstr Surg. 2000; 105:2500–2512.
Article
19. Kim H, Son D, Choi TH, Jung S, Kwon S, Kim J, Han K. Evaluation of an amniotic membrane-collagen dermal substitute in the management of full-thickness skin defects in a pig. Arch Plast Surg. 2013; 40:11–18.
Article
20. Kang BS, Na YC, Jin YW. Comparison of the wound healing effect of cellulose and gelatin: an in vivo study. Arch Plast Surg. 2012; 39:317–321.
Article
21. Jeon H, Kim J, Yeo H, Jeong H, Son D, Han K. Treatment of diabetic foot ulcer using matriderm in comparison with a skin graft. Arch Plast Surg. 2013; 40:403–408.
Article
22. Yang JD, Choi DS, Cho YK, Kim TK, Lee JW, Choi KY, Chung HY, Cho BC, Byun JS. Effect of amniotic fluid stem cells and amniotic fluid cells on the wound healing process in a white rat model. Arch Plast Surg. 2013; 40:496–504.
Article
23. Sung HM, Suh IS, Lee HB, Tak KS, Moon KM, Jung MS. Case reports of adipose-derived stem cell therapy for nasal skin necrosis after filler injection. Arch Plast Surg. 2012; 39:51–54.
Article
24. Salibian AA, Widgerow AD, Abrouk M, Evans GR. Stem cells in plastic surgery: a review of current clinical and translational applications. Arch Plast Surg. 2013; 40:666–675.
Article
25. Choi J, Minn KW, Chang H. The efficacy and safety of platelet-rich plasma and adipose-derived stem cells: an update. Arch Plast Surg. 2012; 39:585–592.
Article
26. Stillaert F, Findlay M, Palmer J, Idrizi R, Cheang S, Messina A, Abberton K, Morrison W, Thompson EW. Host rather than graft origin of Matrigel-induced adipose tissue in the murine tissue-engineering chamber. Tissue Eng. 2007; 13:2291–2300.
Article
27. Min BH, Li TZ. Stem cells in musculoskeletal system for clinical application. J Korean Med Assoc. 2011; 54:491–501.
Article
28. Kanno S, Oda N, Abe M, Saito S, Hori K, Handa Y, Tabayashi K, Sato Y. Establishment of a simple and practical procedure applicable to therapeutic angiogenesis. Circulation. 1999; 99:2682–2687.
Article
29. Dennis RG, Kosnik PE 2nd. Excitability and isometric contractile properties of mammalian skeletal muscle constructs engineered in vitro. In Vitro Cell Dev Biol Anim. 2000; 36:327–335.
Article
30. De Coppi P, Bellini S, Conconi MT, Sabatti M, Simonato E, Gamba PG, Nussdorfer GG, Parnigotto PP. Myoblast-acellular skeletal muscle matrix constructs guarantee a long-term repair of experimental full-thickness abdominal wall defects. Tissue Eng. 2006; 12:1929–1936.
Article
31. Bellamkonda R, Aebischer P. Review: tissue engineering in the nervous system. Biotechnol Bioeng. 1994; 43:543–554.
Article
32. Straley KS, Foo CW, Heilshorn SC. Biomaterial design strategies for the treatment of spinal cord injuries. J Neurotrauma. 2010; 27:1–19.
Article
33. Yoo SJ, Kim J, Lee CS, Nam Y. Simple and novel three dimensional neuronal cell culture using a micro mesh scaffold. Exp Neurobiol. 2011; 20:110–115.
Article
34. Hwang SJ, Kim SW, Choo SJ, Lee BW, Im IR, Yun HJ, Lee SK, Song H, Cho WC, Lee JW. The decellularized vascular allograft as an experimental platform for developing a biocompatible small-diameter graft conduit in a rat surgical model. Yonsei Med J. 2011; 52:227–233.
Article
35. Konig G, McAllister TN, Dusserre N, Garrido SA, Iyican C, Marini A, Fiorillo A, Avila H, Wystrychowski W, Zagalski K, Maruszewski M, Jones AL, Cierpka L, de la Fuente LM, L'Heureux N. Mechanical properties of completely autologous human tissue engineered blood vessels compared to human saphenous vein and mammary artery. Biomaterials. 2009; 30:1542–1550.
Article
36. Stosich MS, Moioli EK, Wu JK, Lee CH, Rohde C, Yoursef AM, Ascherman J, Diraddo R, Marion NW, Mao JJ. Bioengineering strategies to generate vascularized soft tissue grafts with sustained shape. Methods. 2009; 47:116–121.
Article
37. Van Gaalen SM, Kruyt MC, Geuze RE, de Bruijn JD, Alblas J, Dhert WJ. Use of fluorochrome labels in in vivo bone tissue engineering research. Tissue Eng Part B Rev. 2010; 16:209–217.
38. Zhao L, Patel PK, Cohen M. Application of virtual surgical planning with computer assisted design and manufacturing technology to cranio-maxillofacial surgery. Arch Plast Surg. 2012; 39:309–316.
Article
39. Ohba S, Hojo H, Chung UI. Current progress on tissue engineering of bone and cartilage. Endocrinol Metab. 2012; 27:1–11.
Article
40. Yoo JJ, Olson J, Atala A, Kim B. Regenerative medicine strategies for treating neurogenic bladder. Int Neurourol J. 2011; 15:109–119.
Article
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