- Expression of Matrix Metalloproteinase (MMP)-2, MMP-9, Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2 in Adenocarcinomas of The Gallbladder
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Bae JY, Choi J, Chung HC, Park C, Park YN
- KMID: 1725949
- Korean J Pathol.
- 2003 Feb;37(1):1-9.
BACKGROUND: Matrix metalloproteinase (MMP)-2 and MMP-9 degrade type IV collagen and are antagonized by the tissue inhibitors of metalloproteinase (TIMP)-2 and TIMP-1, respectively. METHODS: We studied by immunohistochemistry the expressions of... -
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- Altered Expression of Tissue Inhibitor of Matrix Metalloproteinase-2 in Complicated Mice Heart Secondary to Experimentally Induced Viral Myocarditis
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Kim SS, Eom DW, Woo YJ, Suh JH, Huh J, Hong YM, Choi I
- KMID: 2275603
- Korean J Pathol.
- 2001 Jun;35(3):196-200.
BACKGROUND: The pathogenesis of transition from viral myocarditis to dilated cardiomyopathy is elusive, although the incidence of dilated cardiomyopathy in human is increasing. METHODS: To clarify the role of the... -
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- Expression of Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) in Pancreatic Ductal Adenocarcinoma
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Gu MJ, Bae YK, Choi JH
- KMID: 2275507
- Korean J Pathol.
- 2004 Apr;38(2):73-78.
BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is known to be one of the key molecules for tumor invasion and metastasis. MMP-2 activity is modulated through interaction with the tissue inhibitor of metalloproteinase-2... -
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- The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus
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Shin DS, Park JW, Suh JY, Lee JM
- KMID: 2094713
- J Periodontal Implant Sci.
- 2010 Feb;40(1):33-38.
- doi: 10.5051/jpis.2010.40.1.33
PURPOSE: The purpose of this study was to observe and quantify the expression of interleukin-4 (IL-4), interferon-gamma (IFN-gamma), and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in the gingival tissue of... -
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- Regulation of Matrix Metalloproteinase 2 Expression by an Adenosine A1 Agonist in Trabecular Meshwork Cells
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Baek MJ, Kim KH, Kim JW
- KMID: 2422583
- J Korean Ophthalmol Soc.
- 2018 Oct;59(10):946-952.
- doi: 10.3341/jkos.2018.59.10.946
PURPOSE: We investigated the extent of adenosine A1 agonist-induced expression and regulation of matrix metalloproteinase 2 (MMP-2) synthesis in human trabecular meshwork cells (HTMC). METHODS: Primary HTMC cultures were exposed to... -
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- Expressions of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinase in Great Saphenous Veins of Patients with Varicose Veins
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Huh S, Kwun SH, Park TI, Na MC
- KMID: 2204429
- J Korean Soc Vasc Surg.
- 2004 May;20(1):16-23.
PURPOSE: Although varicose veins are common, the primary cause predisposing to venous reflux of great saphenous vein is controversial. We compared histologic features and expressions of matrix metalloproteinases (MMPs) and... -
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- Immunodetections of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in the Uterine Endometrium
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Woo YJ, Park YS
- KMID: 2260896
- Korean J Obstet Gynecol.
- 1998 Mar;41(3):892-896.
Matrix metalloproteinases[MMP] have the ability to degrade all protein components of the extracellular matrix and are strongly implicated in menstruation. MMPs play a major role in normal tissue remodeling as... -
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- MMP-2 and MMP-9 Expressions in Breast Carcinomas and Relationship with Major Prognostic Factors
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Yoon HK, Park SM
- KMID: 2275508
- Korean J Pathol.
- 2004 Apr;38(2):79-85.
BACKGROUND: MMP-2 and MMP-9 are involved in the degradation of extracellular matrix, and MMP-2 and MMP-9 expressions in breast carcinomas have been reported as a poor prognostic factor. The aim... -
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- Immunolocalization of Matrix Metalloproteinase-2, -9 and Tissue Inhibitor of Metalloproteinase-1, -2 in Suture-induced Corneal Neovascularization
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Heo JG, Kim WS, Hwang DG
- KMID: 2337021
- J Korean Ophthalmol Soc.
- 2002 Jun;43(6):1051-1061.
PURPOSE: Metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) have been linked to the angiogenic process in general. In order to understand the potential roles of MMPs and TIMPs in... -
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- Immunohistochemical study of metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1, -2 in the idiopathic interstitial pneumonia
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Kyung SY, Lim YH, An CH, Park JW, Jeong SH, Shin EK, Ha SY, Lee JW
- KMID: 1620613
- Korean J Med.
- 2003 Aug;65(2):196-204.
BACKGROUND: In the idiopathic interstitial pneumonia (IIP), it has been known that imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is important factor for abnormal remodeling of... -
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- Expression of MMP-2, MT1-MMP, and TIMP-2 mRNA in Breast Carcinomas
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Kim DW, Jin SY, Lee DW
- KMID: 1979368
- Korean J Pathol.
- 2003 Dec;37(6):400-406.
BACKGROUND: The activation of proMMP-2 is induced by membrane type 1-matrix metalloproteinase (MT1-MMP), but inhibited by tissue inhibitors of matrix metalloproteinase type 2 (TIMP-2). This study was carried out to... -
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- The influence of type 2 diabetes mellitus on the expression of inflammatory mediators and tissue inhibitor of metalloproteinases-2 in human chronic periodontitis
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Kim JB, Jung MH, Cho JY, Park JW, Suh JY, Lee JM
- KMID: 1783600
- J Periodontal Implant Sci.
- 2011 Jun;41(3):109-116.
- doi: 10.5051/jpis.2011.41.3.109
PURPOSE: The purpose of this study was to compare and quantify the expression of C-reactive protein (CRP), matrix metalloproteinase (MMP)-14, and tissue inhibitor of metalloproteinases (TIMP)-2 in gingival tissues of... -
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- The Matrix metalloproteinase-2 & -9, Tissue inhibitor of metalloproteinase-1 & -2 mRNA Expression in Invasive Cervical Cancer
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Moon HS, Choi EA, Yoo MY, Chung HW
- KMID: 2076200
- Korean J Obstet Gynecol.
- 2001 Mar;44(3):532-539.
OBJECTIVE: Invasive cancer cells penetrate the extracellular matrix(ECM), including basement membrane during the metastatic cascades. Matrix metalloproteinases(MMPs) play a critical role in tumor invasion and metastasis and their activities are... -
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- Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease
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Yun KW, Yun SW, Lee JJ, Chae SA, Lim IS, Choi ES, Yoo BH, Lee MK
- KMID: 2073576
- Korean J Pediatr.
- 2010 Apr;53(4):510-518.
- doi: 10.3345/kjp.2010.53.4.510
PURPOSE: Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary... -
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- Expression of matrix-metalloproteinases(MMP-2,9) and tissue inhibitor of matrix-metalloproteinase(TIMP-2) in cervical carcinoma
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Jeon CS, Lee SG, Kim SB, Lee JH
- KMID: 2262175
- Korean J Obstet Gynecol.
- 2001 Jan;44(1):93-100.
OBJECTIVE: This study was performed to investigate the role of matrix-metalloproteinases(MMP-2,9) and tissue inhibitor of matrix-metalloproteinase(TIMP-2) in tumor metastasis and to correlate the expression of MMP-2,9 and TIMP-2 in cervical... -
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- Expression of Matrix Metalloproteinase and Tissue Inhibitors of Matrix Metalloproteinase in Malignant Lymphoma
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Lee AW, Lee AH, Kang CS, Kim BK
- KMID: 1979389
- Korean J Pathol.
- 2000 Apr;34(4):249-256.
Matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitors of matrix metalloproteinases, TIMPs) play essential roles in the remodelling of the extracellular matrix. The balance between MMPs and TIMPs is altered... -
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- Effects of Bisphosphonate on the Expression of Matrix Enzymes during Endochondral Ossification
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Yoo HI, Jung SY, Kim SH
- KMID: 2068826
- Korean J Phys Anthropol.
- 2015 Sep;28(3):155-165.
- doi: 10.11637/kjpa.2015.28.3.155
Bisphosphonates have been reported to have chondroprotective activities in addition to its original functions. However, mechanisms for these just began to be elucidated. Under the hypothesis that bisphosphonates may regulate... -
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- Clinical significance of the serum levels of matrix metalloproteinases and the tissue inhibitors of metalloproteinases for gastric and colorectal cancer patients
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Yoon SJ, Shim KN, Cho YK, Song HJ, Jung SA, Kim TH, Yoo K
- KMID: 2256411
- Korean J Med.
- 2007 May;72(5):491-500.
BACKGROUND: Matrix metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinase (TIMPs), are important factors related to invasion and metastasis in various human cancers. Different results have been reported... -
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- An Immunohistochemical Study on the Expression of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Angiogenesis in Human Laryngeal Squamous Cell Carcinoma
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Kim CN, Chung SM, Min JH, Kim SS, Kim MY
- KMID: 2074281
- Korean J Otolaryngol-Head Neck Surg.
- 1997 May;40(5):670-681.
The clinical staging systems for laryngeal cancer is limited as a prognostic indicator because of different biological characteristics of cancer in this region. To determine biological characteristics of laryngeal cancer... -
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- Expressions of MMP-2, MMP-9, TIMP-1, and TIMP-2 as prognostic factors in endometrial cancer
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Choi JR, Lee TH, Oh YL, Lee CJ, Kim WG
- KMID: 1979502
- Korean J Gynecol Oncol.
- 2008 Mar;19(1):57-67.
- doi: 10.3802/kjgo.2008.19.1.57
OBJECTIVE: Homeostasis of the extracellular matrix (ECM) is maintained by the action of a specific system of proteolytic enzymes known as matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP).... -
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