- The Apical Junctional Complex in Respiratory Diseases
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Jang AS
- KMID: 1889755
- Chonnam Med J.
- 2014 Apr;50(1):1-5.
- doi: 10.4068/cmj.2014.50.1.1
The epithelium, including the respiratory system, acts as a selective gate between the outside environment and underlying tissue. Epithelial cells are polarized due to the formation of the apical junctional... -
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- Uterine expression of tight junctions in the Canine uterus
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Ahn C, Shin DH, Lee D, Kang HY, Jeung EB
- KMID: 2169092
- J Biomed Res.
- 2015 Sep;16(3):98-103.
- doi: 10.12729/jbr.2015.16.3.098
Tight junctions (TJs) form continuous intercellular contacts in intercellular junctions. TJs involve integral proteins such as occludin (OCLN) and claudins (CLDNs) as well as peripheral proteins such as zona occludens-1... -
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- Electron Microscopic Observation of Experimentally Induced Comedones in Rabbit
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Myung KB
- KMID: 2231483
- Korean J Dermatol.
- 1987 Aug;25(4):492-499.
Accurnulation of keratinized cells within the infundibulum of pilosebaceous canal is important in the pathogenesis of acne. Light and electron microscopic study of experimentally induced comedones, from the rabbit's external... -
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- Altered Transendothelial Transport of Hormones as a Contributor to Diabetes
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Yoon N, Dang TQ, Chasiotis , Kelly SP, Sweeney G
- KMID: 2280699
- Diabetes Metab J.
- 2014 Apr;38(2):92-99.
- doi: 10.4093/dmj.2014.38.2.92
The vascular endothelium is a dynamic structure responsible for the separation and regulated movement of biological material between circulation and interstitial fluid. Hormones and nutrients can move across the endothelium... -
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- Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases
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Lee SH
- KMID: 1807372
- Intest Res.
- 2015 Jan;13(1):11-18.
- doi: 10.5217/ir.2015.13.1.11
Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of macromolecules. The TJ is multi-protein complex that forms a selective permeable seal between adjacent epithelial cells and demarcates... -
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- Relevance of Ultrastructural Alterations of Intercellular Junction Morphology in Inflamed Human Esophagus
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Liu CC, Lee JW, Liu TT, Yi CH, Chen CL
- KMID: 2326232
- J Neurogastroenterol Motil.
- 2013 Jul;19(3):324-331.
BACKGROUND/AIMS: Detailed characterization of the ultrastructural morphology of intercellular space in gastroesophageal reflux disease has not been fully studied. We aimed to investigate whether subtle alteration in intercellular space structure... -
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- Increase in Transepithelial Resistance Mouse Sertoli Cells by Leydig Cells Coculture
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Gye MC
- KMID: 2298659
- Korean J Androl.
- 2001 Aug;19(2):115-118.
PURPOSE: To verify the regulation of transepithelial resistance (TER) of Sertoli cells by Leydig cells in mouse. MATERIALS AND METHODS: Primary culture of Sertoli cells was established on cell culture plate... -
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- Changes of Tight Junction and Epithelial Cells after Treatment of Cadmium
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Lee SJ, Kim KY, Kim DJ, Chung YH, Kim SS, Lee WB, Cho DY, Sohn DS
- KMID: 1512957
- Korean J Phys Anthropol.
- 2007 Mar;20(1):69-82.
Cadmium (Cd) affects cell proliferation, differentiation, apoptosis and other cellular activities and can cause numerous molecular lesions that would be relevant to carcinogenesis. The mechanism of adverse effects of Cd... -
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- Oxidative Stress Induced--Expression Changes of Zonular Occludens--1 in Tight Junction
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Sohn D, Lee H, Kim D, Choi H, Lee K, Cho H, Kim S, Lee J, Jeong Y, Kim S, Lee W, Kim K
- KMID: 1609551
- Korean J Phys Anthropol.
- 2004 Dec;17(4):281-288.
The homeostasis of microenvironment in central nervous system, essential for normal function, is maintained by blood-brain barrier (BBB). ZO-1 in tight junctions (TJs) plays an important role in maintaining BBB... -
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- Ultrastrual Study on Changes of the Capillaries in Experimental Brain Infarcts of Rats
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Cho JH, Lee JH, Juhng SW
- KMID: 2068308
- J Korean Neurosurg Soc.
- 1987 Mar;16(1):203-216.
Experimental brain infarcts in rats were studied light and electron microscopically to investigate the factor(s) controlling contrast enhancement on CT scans of the infarcts. Brain infarction was induced by injection... -
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- Electron Microsopic study of Diabetic Preretinal Membranes
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Rhee KC, Huh K
- KMID: 2108201
- J Korean Ophthalmol Soc.
- 1997 Apr;38(4):628-636.
We conducted electron microscopic observation of twenty diabetic preretinal membranes removed during vitrectomy. Membranes were composed of many different types of cells and vessels and intercellular substance. Vessels of develping... -
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- Effects of High Glucose and Dexamethasone on the Permeability in Trabecular Meshwork Cells
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Kang SH, Kim JW
- KMID: 2406960
- J Korean Ophthalmol Soc.
- 2018 Mar;59(3):252-260.
- doi: 10.3341/jkos.2018.59.3.252
PURPOSE: To investigate the effects of high glucose (HG) and dexamethasone (DEX) on the survival and permeability of trabecular meshwork cells (HTMC), and associated changes in tight junctions. METHODS: Primary cultured... -
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- Regional Variation in the Expression of 'Tight Junction' Protein 'Occludin' in the Epidermis
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Yoo SR, Kim JS, Ko JY, Lee CW
- KMID: 2302105
- Korean J Dermatol.
- 2008 Feb;46(2):196-201.
BACKGROUND: 'Tight junctions (TJ)' have recently been identified in the granular cell layer of the human epidermis, where they contribute to the normal adhesion between keratinocytes and to the physiologic... -
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- Physiological understanding of host-microbial pathogen interactions in the gut
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Lee SJ, Choi SH, Han HJ
- KMID: 2368745
- Korean J Vet Res.
- 2016 Jun;56(2):57-66.
- doi: 10.14405/kjvr.2016.56.2.57
The gut epithelial barrier, which is composed of the mucosal layer and the intestinal epithelium, has multiple defense mechanisms and interconnected regulatory mechanisms against enteric microbial pathogens. However, many bacterial... -
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- Freeze-fracture Scanning Electron Microscopy of the Human Retina
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Lee SC, Kwon OW, Davidorf F
- KMID: 1949589
- J Korean Ophthalmol Soc.
- 1991 Dec;32(12):1080-1085.
Our current understanding of the ultrastructure of the retina has been gained using transmis sion electron microscopy (TEM) of thin sections. Scanning electron microscopy was proven to be a very... -
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- A Prospective Study of Eosinophilic Esophagitis and the Expression of Tight Junction Proteins in Patients with Gastroesophageal Reflux Disease Symptoms
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Okimoto K, Arai M, Ishigami H, Saito K, Minemura S, Maruoka D, Matsumura , Nakagawa T, Katsuno T, Suzuki M, Nakatani Y, Yokosuka O
- KMID: 2404714
- Gut Liver.
- 2018 Jan;12(1):30-37.
- doi: 10.5009/gnl16600
BACKGROUND/AIMS: Eosinophilic esophagitis (EoE) is often erroneously diagnosed as gastroesophageal reflux disease (GERD). The aim of this study is to investigate the prevalence of EoE and the expression of tight... -
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- German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells
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Lee KE, Jee HM, Hong JY, Kim MN, Oh MS, Kim YS, Kim KW, Kim KE, Sohn MH
- KMID: 2426337
- Yonsei Med J.
- 2018 Dec;59(10):1222-1231.
- doi: 10.3349/ymj.2018.59.10.1222
PURPOSE: Cockroach exposure is a pivotal cause of asthma. Tight junctions are intercellular structures required for maintenance of the barrier function of the airway epithelium, which is impaired in this... -
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- Indol-3-Carbinol Regulated Tight Junction Permeability and Associated-Protein Level and Suppressed Cell Invasion in Human Colon Cancer Cell Line, HT-29
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Kim SO, Choi YH, Choe WK
- KMID: 2261191
- Korean J Nutr.
- 2008 Jan;41(1):13-21.
To determine whether indol-3-carbinol (I3C, C9H9NO), an autolysis product of a glucosinolate and a glucobrassicin in vegetables, regulated tight junction proteins (TJ) and suppressed cell invasion in colon cancer cells,this... -
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- Reduced Expression of Claudin-7 Correlates with Invasiveness and Nuclear Grade of Breast Carcinomas
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Seok SH, Kang SH, Lee SJ, Hwang TY, Bae YK
- KMID: 1521664
- Korean J Pathol.
- 2007 Jun;41(3):158-164.
Background : Claudins are important components of the tight junctions in the intercellular barriers and cell polarity. Among them, claudin-7 is down-regulated in breast cancers compared with the normal breast... -
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- Expression of Claudin-1 in the Fetal Skin during the Developmental Stage
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Kim HK, Ko YS, Joh OJ, Lee JS, Song KY
- KMID: 1771543
- Korean J Dermatol.
- 2008 Aug;46(8):1048-1055.
BACKGROUND: Claudins are integral membrane proteins at tight junctions of simple epithelium and have an important role in cell-cell adhesion and barrier function. Their altered expression modifies the biological function... -
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