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Neutraceuticals may supplement pharmaceutical treatment of neuropathic pain

Kim WM

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Targeting nerve growth factor for pain relief: pros and cons

Jaffal S, Khalil R

Nerve growth factor (NGF) is a neurotrophic protein that has crucial roles in survival, growth and differentiation. It is expressed in neuronal and non-neuronal tissues. NGF exerts its effects via...
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A critical factor in resistant piriformis syndrome cases: awareness of sacrotuberous ligament pain

Dede BT, Oğuz M, Ada A, Alyanak B, Bağcıer F

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Efficacy and safety of low-dose naltrexone for the management of fibromyalgia: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

Vatvani AD, Patel P, Hariyanto TI, Yanto TA

Background: Fibromyalgia is characterized by the presence of chronic widespread pain that may impair patient’s quality of life. Currently, the use of naltrexone as a therapeutic agent for fibromyalgia is...
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Ultrasound-guided transoral pterygopalatine fossa block: cadaveric elaboration of a novel technique

Chang KV, Lin JA, Tseng TJ, Hsu CW, Liao TR, Wu WT, Özçakar L

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Low level laser therapy alleviates mechanical allodynia in a postoperative and neuropathic pain model and alters the levels of inflammatory factors in rats

Han X, Jang Kc, Kim WM, Lee HG

Background: This study aimed to investigate the analgesic and preventive effect of low-level laser therapy (LLLT) on the incisional pain model and spinal nerve ligation (SNL) model in rats and...
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Methylcobalamin as a candidate for chronic peripheral neuropathic pain therapy: review of molecular pharmacology action

Ramadhani A, Astuti I, Widiastuti MG, Purwanti N

Chronic peripheral neuropathic pain therapy currently focuses on modulating neuroinflammatory conditions. Methylcobalamin (MeCbl), a neuroregenerative agent, modulates neuroinflammation. This review aimed to explore the molecular pharmacology action of MeCbl as...
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Down-regulation of microRNA-382-5p reduces neuropathic pain by targeting regulation of dual specificity phosphatase-1

Xu A, Shen H, Mei S, Wang Z, Xie Q, Cui H, Chu Y, Feng B

Background: MicroRNA (miRNA) plays a crucial role in neuropathic pain (NP) by targeting mRNAs. This study aims to analyze the regulatory function and mechanism of miR-382-5p/dual specificity phosphatase-1 (DUSP1) axis...
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Effect of ultrasound-guided ilioinguinaliliohypogastric nerve block on chronic pain in patients undergoing open inguinal hernia surgery under spinal anesthesia: a randomized doubleblind study

Sahoo RK, Pradhan A, Samanta P, Senapati LK, Satapathy GC

Background: Pre-operative ilioinguinal-iliohypogastric nerve block (II-IHNB) has a proven role in lessening acute postoperative pain and opioid consumption following hernia repair. However, its role in preventing post-herniorrhaphy groin pain (PHGP)...
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Impact of general anesthesia type on chronic postsurgical pain following video-assisted thoracoscopic surgery for lung cancer: a retrospective propensity-matched cohort study

Yoon SH, Choi S, Yoon S, Na KJ, Bahk J, Lee HJ

Background: Anesthetic agents are potential modifiable factors that can mitigate chronic postsurgical pain (CPSP) development. This study aimed to investigate the association between propofol-based total intravenous anesthesia (TIVA) and the...
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Assessment of ultrasound-guided intercostal nerve block for acute herpes zoster and its' possible prophylaxis for postherpetic neuralgia: a retrospective and case-controlled trial

Li X, Yuan R, Yang Y, Qin Z, Fu R

Background: This study aimed to compare the intercostal nerve block (ICNB) and thoracic paravertebral block (TPVB) for acute herpes zoster-associated pain (ZAP) and possible prophylaxis for post-herpetic neuralgia (PHN). Methods: This...
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