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Two Evaluation Budgets for the Measurement Uncertainty of Glucose in Clinical Chemistry

Chen H, Zhang L, Bi X, Deng X

BACKGROUND: Measurement uncertainty characterizes the dispersion of the quantity values attributed to a measurand. Although this concept was introduced to medical laboratories some years ago, not all medical researchers are...
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Emergence of Clostridium difficile Ribotype 027 in Korea

Kim H, Lee Y, Moon HW, Lim CS, Lee K, Chong Y

BACKGROUND: Clostridium difficile infection (CDI) has markedly risen and is associated with hypervirulent ribotype 027 outbreaks in North America and Europe since 2003. The aims of this study were to...
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Leptin:Adiponectin Ratio and Metabolic Syndrome in the General Japanese Population

Kotani K, Sakane N

BACKGROUND: Circulating leptin:adiponectin ratio (L:A) is a potential surrogate marker for cardiometabolic diseases; however, the relationship of the L:A with the occurrence of metabolic syndrome (MetS) has not yet been...
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Microangiopathic Hemolytic Anemia as the First Manifestation of Metastatic Signet Ring Cell Carcinoma of Unknown Origin: A Case Report and Review of Literature

Shin SY, Park H, Chae SW, Woo HY

Microangiopathic hemolytic anemia (MAHA) occurs occasionally as a paraneoplastic syndrome in some solid tumors, but MAHA accompanied by signet ring cell carcinoma of an unknown origin is very rare. In...
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Comparative Quantitative Analysis of Cluster of Differentiation 45 Antigen Expression on Lymphocyte Subsets

Im M, Chae H, Kim T, Park HH, Lim J, Oh EJ, Kim Y, Park YJ, Han K

BACKGROUND: Since the recent introduction of radioimmunotherapy (RIT) using antibodies against cluster of differentiation (CD) 45 for the treatment of lymphoma, the clinical significance of the CD45 antigen has been...
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Acquired Factor X Deficiency in Light Chain Amyloidosis: A Report of 2 Korean Cases

Ma Y, Kwon EH, Lee JE, Kim K, Kim HJ, Kim SH

Amyloidosis is a heterogeneous group of diseases in which misfolding of extracellular proteins is the pathogenic factor. Light chain amyloidosis (AL) is the most common form of amyloidosis, and the...
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Evaluation of the MicroScan MICroSTREP Plus Antimicrobial Panel for Testing beta-Hemolytic Streptococci and Viridans Group Streptococci

Kim SJ, Uh Y, Jang IH, Lee KS, Park SD, Yoon KJ

BACKGROUND: In order to determine the clinical usefulness of the MicroScan (Siemens Healthcare Diagnostics, USA) MICroSTREP plus antimicrobial panel (MICroSTREP) for testing antimicrobial susceptibility of beta-hemolytic streptococci (BHS) and viridans...
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Human Bocavirus in Patients with Respiratory Tract Infection

Kim JS, Lim CS, Kim YK, Lee KN, Lee CK

BACKGROUND: Human bocavirus (HBoV) is a newly identified viral pathogen, and its clinical epidemiology and significance in respiratory infections have not yet been completely elucidated. We investigated the prevalence of...
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Subcutaneous Phaeohyphomycosis Caused by Phaeoacremonium Species in a Kidney Transplant Patient: The First Case in Korea

Choi J, Lee Y, Chung HS, Koo JS, Yong D, Kim YS, Lee K, Chong Y

Phaeohyphomycosis is a subcutaneous infection caused by dark pigmented fungi, including fungi of the species Phaeoacremonium, Alternaria, Exophiala, and Pyrenochaeta. In August 2005, a 54-yr-old man who had received a...
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Evaluation of the Diagnostic Performance of Fibrin Monomer in Disseminated Intravascular Coagulation

Park KJ, Kwon EH, Kim HJ, Kim SH

BACKGROUND: Fibrin-related markers (FRM) such as fibrin monomer (FM) and D-dimer (DD) are considered useful biological markers for the diagnosis of disseminated intravascular coagulation (DIC). However, no studies on the...
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Mycobacterial Infection after Intravesical Bacillus Calmette-Guerin Treatment for Bladder Cancer: A Case Report

Park CH, Jang MA, Ahn YH, Hwang YY, Ki CS, Lee NY

Bacillus Calmette-Guerin (BCG) has been traditionally used as a vaccine against tuberculosis. Further, intravesical administration of BCG has been shown to be effective in treating bladder cancer. Although BCG contains...
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Streptococcus suis Meningitis with Bilateral Sensorineural Hearing Loss

Huh HJ, Park KJ, Jang JH, Lee M, Lee JH, Ahn YH, Kang CI, Ki CS, Lee NY

Streptococcus suis infection is an emerging zoonosis in Asia. The most common disease manifestation is meningitis, which is often associated with hearing loss and cochleovestibular signs. S. suis infection in...
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Reliable, Accurate Determination of the Leukocyte Differential of Leukopenic Samples by Using Hematoflow Method

Jo Y, Kim SH, Koh K, Park J, Shim YB, Lim J, Kim Y, Park YJ, Han K

BACKGROUND: Hematology analyzers may ineffectively recognize abnormal cells, and manual differential counts may be imprecise for leukopenic samples. We evaluated the efficacy of the Hematoflow method for determining the leukocyte...
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Heterogeneous Spectrum of CFTR Gene Mutations in Korean Patients with Cystic Fibrosis

Jung H, Ki CS, Koh WJ, Ahn KM, Lee SI, Kim JH, Ko JS, Seo JK, Cha SI, Lee ES, Kim JW

BACKGROUND: Cystic fibrosis (CF) is one of the most common hereditary disorders among Caucasians. The most common mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene have been well...
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Individual Variation in Growth Factor Concentrations in Platelet-rich Plasma and Its Influence on Human Mesenchymal Stem Cells

Cho HS, Song IH, Park SY, Sung MC, Ahn MW, Song KE

BACKGROUND: The objective of this study was to explore whether individual variations in the concentration of growth factors (GFs) influence the biologic effects of platelet-rich plasma (PRP) on human mesenchymal...
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Detection of alpha-thalassemia-1 Southeast Asian and Thai Type Deletions and beta-thalassemia 3.5-kb Deletion by Single-tube Multiplex Real-time PCR with SYBR Green1 and High-resolution Melting Analysis

Pornprasert S, Wiengkum T, Srithep S, Chainoi I, Singboottra P, Wongwiwatthananukit S

BACKGROUND: Prevention and control of thalassemia requires simple, rapid, and accurate screening tests for carrier couples who are at risk of conceiving fetuses with severe thalassemia. METHODS: Single-tube multiplex real-time PCR...
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Diagnostic Performance of High-Sensitivity Troponin T, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A Assays for Triage of Patients with Acute Myocardial Infarction

Khan DA, Sharif MS, Khan FA

BACKGROUND: Early diagnosis is the cornerstone of management of acute myocardial infarction (AMI). We aimed to compare the diagnostic accuracy of high-sensitivity troponin T (hs-cTnT) with myeloperoxidase (MPO) and pregnancy-associated...
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