- Intervention with costimulatory pathways as a therapeutic approach for graft-versus-host disease
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Kwon B
- KMID: 964662
- Exp Mol Med.
- 2010 Oct;42(10):675-683.
- doi: 10.3858/emm.2010.42.10.071
Graft-versus-host disease (GVHD) is mediated by mature donor T cells contained in the hematopoietic stem cell graft. During the development of GVHD, signaling through a variety of costimulatory receptors plays... -
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- Lymphoepithelioma-like Carcinoma of the Urinary Bladder
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Yun HK, Yun SI, Lee YH, Kang KM, Kwak EK, Kim JS, Cho SR, Kwon JB
- KMID: 1779242
- J Korean Med Sci.
- 2010 Nov;25(11):1672-1675.
- doi: 10.3346/jkms.2010.25.11.1672
A 78-yr-old woman presented with gross hematuria for 2 weeks. On cystoscopy, a frond-like mass was observed at the bladder trigone. Transurethral resection of bladder tumor was performed for the... -
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- Comparative Quantitative Analysis of Cluster of Differentiation 45 Antigen Expression on Lymphocyte Subsets
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Im M, Chae H, Kim T, Park HH, Lim J, Oh EJ, Kim Y, Park YJ, Han K
- KMID: 1735845
- Korean J Lab Med.
- 2011 Jul;31(3):148-153.
- doi: 10.3343/kjlm.2011.31.3.148
BACKGROUND: Since the recent introduction of radioimmunotherapy (RIT) using antibodies against cluster of differentiation (CD) 45 for the treatment of lymphoma, the clinical significance of the CD45 antigen has been... -
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- Helicobacter pylori in Human Stomach: Can It Be Called Mutualism or a Disease?
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Cheung DY, Kim TH
- KMID: 1792831
- Korean J Gastroenterol.
- 2012 May;59(5):329-337.
- doi: 10.4166/kjg.2012.59.5.329
Helicobacter pylori (H. pylori) has been a major concern as a gastric pathogen with unique features since discovered in the end of the 20th century. Recent data on comparative genome... -
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- Intratumoral Administration of Secondary Lymphoid Chemokine and Unmethylated Cytosine-phosphorothioate-guanine Oligodeoxynucleotide Synergistically Inhibits Tumor Growth in Vivo
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Oh SM, Oh K, Lee DS
- KMID: 1785982
- J Korean Med Sci.
- 2011 Oct;26(10):1270-1276.
- doi: 10.3346/jkms.2011.26.10.1270
Secondary lymphoid tissue chemokine (SLC), which is expressed in T cell zones of secondary lymphoid organs, including the spleen and lymph nodes, strongly recruits both T lymphocytes and mature dendritic... -
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- Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
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Kim S, Chung HW, Kong HY, Lim JB
- KMID: 2374187
- Yonsei Med J.
- 2017 Jan;58(1):43-50.
- doi: 10.3349/ymj.2017.58.1.43
PURPOSE: To identify new immunogenic HLA-A*33;03-restricted epitopes from the human papillomavirus (HPV) 16 E7 protein for immunotherapy against cervical cancer. MATERIALS AND METHODS: We synthesized fourteen overlapping 15-amino acid peptides and... -
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- Effects of Laughter Therapy on Depression, Quality of Life, Resilience and Immune Responses in Breast Cancer Survivors
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Cho EA, Oh HE
- KMID: 1015478
- J Korean Acad Nurs.
- 2011 Jun;41(3):285-293.
- doi: 10.4040/jkan.2011.41.3.285
PURPOSE: In this study, the effects of laughter therapy on levels of depression, quality of life, resilience and immune responses in breast cancer survivors were examined. METHODS: A quasi-experimental nonequivalent control... -
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- Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells
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Park H, Park OJ, Shin J, Choi Y
- KMID: 1116197
- Exp Mol Med.
- 2005 Dec;37(6):524-532.
Receptor activator of NFkappaB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,... -
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- Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders
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Cai Q, Chen K, Young KH
- KMID: 2155398
- Exp Mol Med.
- 2015 Jan;47(1):e133.
- doi: 10.1038/emm.2014.105
Epstein-Barr virus, a ubiquitous human herpesvirus, can induce both lytic and latent infections that result in a variety of human diseases, including lymphoproliferative disorders. The oncogenic potential of Epstein-Barr virus... -
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- Introduction of the CIITA gene into tumor cells produces exosomes with enhanced anti-tumor effects
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Lee YS, Kim SH, Cho JA, Kim CW
- KMID: 1009967
- Exp Mol Med.
- 2011 May;43(5):281-290.
- doi: 10.3858/emm.2011.43.5.029
Exosomes are small membrane vesicles secreted from various types of cells. Tumor-derived exosomes contain MHC class I molecules and tumor-specific antigens, receiving attention as a potential cancer vaccine. For induction... -
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- Clinical Usefulness of T-SPOT.TB Test for the Diagnosis of Tuberculosis
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Kim HS, Kim CH, Hur M, Hyun IG, Park MJ, Song W, Park JY, Kang HJ, Lee KM
- KMID: 1096804
- Korean J Lab Med.
- 2010 Apr;30(2):171-177.
- doi: 10.3343/kjlm.2010.30.2.171
BACKGROUND: Tuberculosis-specific ELISPOT assay (T-SPOT.TB, Oxford Immunotec, UK) is a test that detects interferon-gamma producing T-cells after stimulating patient's lymphocytes with two kinds of tuberculosis-specific antigens (ESAT-6 and CFP-10). We... -
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- Inflammatory Bowel Diseases and Enteric Microbiota
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Kim JM
- KMID: 1775921
- Korean J Gastroenterol.
- 2010 Jan;55(1):4-18.
- doi: 10.4166/kjg.2010.55.1.4
Intestinal mucosal layers are colonized by a complex microbiota that provides beneficial effects under normal physiological conditions, but is capable of contributing to chronic inflammatory disease such as inflammatory bowel... -
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- The enhanced expression of IL-17-secreting T cells during the early progression of atherosclerosis in ApoE-deficient mice fed on a western-type diet
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Jeon US, Choi JP, Kim YS, Ryu SH, Kim YK
- KMID: 2155655
- Exp Mol Med.
- 2015 May;47(5):e163.
- doi: 10.1038/emm.2015.19
Atherosclerosis is a chronic progressive inflammatory disorder and the leading cause of cardiovascular mortality. Here we assessed the dynamic changes of T-cell-derived cytokines, such as inteferon (IFN)-gamma, interleukin (IL)-17 and... -
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- Predictive Value of Conjointly Examined IL-1ra, TNF-R I, TNF-R II, and RANTES in Patients with Primary Glomerulonephritis
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Zwiech R
- KMID: 1429194
- J Korean Med Sci.
- 2013 Feb;28(2):261-267.
- doi: 10.3346/jkms.2013.28.2.261
Interleukin-1 receptor antagonist (IL-1ra), tumor necrosis factor soluble receptors (sTNF-R) type I and II, and regulated upon activation, normal T-cell expressed and secreted (RANTES) play an important role in the... -
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- EC-18, a Synthetic Monoacetyldiacylglyceride, Inhibits Hematogenous Metastasis of KIGB-5 Biliary Cancer Cell in Hamster Model
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Kim MH, Chang HM, Kim TW, Lee SK, Park JS, Kim YH, Lee TY, Jang SJ, Suh CW, Lee TS, Kim SH, Lee SG
- KMID: 1779166
- J Korean Med Sci.
- 2009 Jun;24(3):474-480.
- doi: 10.3346/jkms.2009.24.3.474
EC-18 (monoacetyldiacylglyceride) stimulates T cell production of IL-2, IL-4, IL-12, IFN-gamma, and GM-CSF in vitro. To study the effects of these cytokines stimulated by EC-18 on cancer cells, we applied... -
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