- Immunological abnormalities in patient with IgA nephropathy
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Ihm CG, Woo JT, Chang YW, Kwon OS, Kim MJ
- KMID: 1421234
- J Korean Med Sci.
- 1986 Sep;1(1):43-48.
- doi: 10.3346/jkms.1986.1.1.43
T cell immunity and phagocytic activity were studied in the blood of patients with IgA nephropathy in order to clarify their roles in the pathogenesis of IgA nephropathy. The percentages... -
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- Immunology of Hepatitis C: Clinical Significance of T Cell Response
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Shin EC
- KMID: 760641
- Korean J Hepatol.
- 2006 Jun;12(2):140-153.
Hepatitis C virus (HCV) infection is a worldwide problem in terms of public health. It causes chronic hepatitis C in 60-80% of patients after acute hepatitis C. Chronic hepatitis C... -
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- Maintenance of CD8+T-cell anergy by CD4+CD25+ regulatory T cells in chronic graft-versus-host disease
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Kim J, Kim HJ, Choi WS, Nam SH, Cho HR, Kwon B
- KMID: 1098083
- Exp Mol Med.
- 2006 Oct;38(5):494-501.
In a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD), donor CD8+T cells rapidly fall into anergy to host cells, while donor CD4+T cells hyperactivate B cells... -
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- Regulatory T Cells - An Emerging Role in Transplantation
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Feng G, Wood K
- KMID: 1726158
- Yonsei Med J.
- 2004 Dec;45(6):968-977.
- doi: 10.3349/ymj.2004.45.6.968
No abstract available. -
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- Gamma/delta T lymphocytes in the BCG granulomatous lesions
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Kim DS, Lee KY, Yang WI, Han SJ, Hwang EH
- KMID: 699909
- Yonsei Med J.
- 1996 Oct;37(5):319-324.
- doi: 10.3349/ymj.1996.37.5.319
Recent studies in man and animal models have demonstrated that TCR-gamma delta-bearing T cells (gamma delta T cells) are activated by mycobacteria and accumulate in the sites of mycobacterial infection.... -
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- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
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La S, Kim E, Kwon B
- KMID: 1056231
- Exp Mol Med.
- 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive... -
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- CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta
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Oh KI, Kim BK, Ban YL, Choi EY, Jung KC, Lee IS, Park SH
- KMID: 1094658
- Exp Mol Med.
- 2007 Apr;39(2):176-184.
We investigated the co-stimulatory role of a cell-surface protein, CD99. Co-ligation of CD99 and suboptimal CD3 induced T-cell activation to a level comparable to that obtained with optimal CD3 or... -
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- Antibody Response of Mouse Splenocytes Using Mixture of Supernatants of Thymocytes, Adherent and Non-adherent Splenocytes: In-vitro Immunization-II
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Kim D, Noh GW, Kim DH, Kwon OH
- KMID: 1421475
- J Korean Med Sci.
- 1990 Mar;5(1):25-31.
- doi: 10.3346/jkms.1990.5.1.25
We adapted one of the in-vitro immunization methods to induce antibody responses and confirmed the success of the immunization by enzyme-linked immunosorbent assay (ELISA) without hybridization. We have previously reported... -
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- The presence of CD8+ invariant NKT cells in mice
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Lee H, Hong C, Shin J, Oh S, Jung S, Park YK, Hong S, Lee GR, Park SH
- KMID: 1099863
- Exp Mol Med.
- 2009 Dec;41(12):866-872.
- doi: 10.3858/emm.2009.41.12.092
Invariant natural killer T (iNKT) cells develop in the thymus upon recognition of CD1d expressed on developing thymocytes. Although CD4 and CD8 coreceptors are not directly involved in the interaction... -
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- Analysis of the immunologic mechanism of intravesical bacillus Calmette-Guerin therapy for superficial bladder tumors: distribution and function of immune cells
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Chung JY, Lee ES, Lee WJ, Kim HH, Min KJ, Lee CW
- KMID: 1421965
- J Korean Med Sci.
- 1993 Apr;8(2):135-144.
- doi: 10.3346/jkms.1993.8.2.135
Intravesical bacillus Calmette-Guerin (BCG) administration has been used as an adjuvant therapy after transurethral resection for superficial bladder cancer, but the exact mechanisms of its antitumor activity are not yet... -
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- Suppression of CD4+ T-Cells in the Spleen of Mice Infected with Toxoplasma gondii KI-1 Tachyzoites
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Kim WH, Shin EH, Kim JL, Yu SY, Jung BK, Chai JY
- KMID: 1104700
- Korean J Parasitol.
- 2010 Dec;48(4):325-329.
- doi: 10.3347/kjp.2010.48.4.325
Toxoplasma gondii KI-1, a recent new isolate from Korea, shows similar pathogenicity and infectivity to mice compared to the virulent RH strain. To understand characteristics of host immunity, including immune... -
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- Fulminant Epstein-Barr Virus-associated T-cell Lymphoproliferative Disorder in an Immunocompetent Middle-aged Man Presenting with Chronic Diarrhea and Gastrointestinal Bleeding
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Abdul-Ghafar J, Kim JW, Park KH, Cho MY
- KMID: 1777852
- J Korean Med Sci.
- 2011 Aug;26(8):1103-1107.
- doi: 10.3346/jkms.2011.26.8.1103
The World Health Organization (WHO) recently defined systemic Epstein-Barr virus (EBV)-positive T-cell lymphoproliferative disorders (LPD) of childhood as a life-threatening illness. However, this rare disease has not been extensively studied.... -
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- Expression of Hepatitis C Virus Core Protein in Hepatocytes Does Not Modulate Proliferation or Apoptosis of CD8+ T Cells
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Jin YH, Crispe IN, Park S
- KMID: 2428300
- Yonsei Med J.
- 2005 Dec;46(6):827-834.
Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein... -
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- T Cell-specific Immunosuppression Using Tautomycetin or PTD-conjugated Protein Drugs
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Chae WJ, Choi JM, Yang JJ, Lee SK
- KMID: 1726159
- Yonsei Med J.
- 2004 Dec;45(6):978-990.
- doi: 10.3349/ymj.2004.45.6.978
No abstract available. -
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- Clinical Significance of Monitoring Circulating CD4+CD25+ Regulatory T Cells in Kidney Transplantation during the Early Posttransplant Period
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Kim SH, Oh EJ, Ghee JY, Song HK, Han DH, Yoon HE, Choi BS, Yoon SK, Choi JY, Moon IS, Kim DG, Yang CW
- KMID: 1778153
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S135-S142.
- doi: 10.3346/jkms.2009.24.S1.S135
The CD4+CD25+ T regulatory cells (Tregs) play an important role in immune tolerance in experimental transplantation but the clinical significance of circulating Tregs in the peripheral blood is undetermined. In... -
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- Immunosuppression by T regulatory cells in cows infected with Staphylococcal superantigen
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Chang BS, Bohach GA, Lee SU, Davis WC, Fox LK, Ferens WA, Seo KS, Koo HC, Kwon NH, Park YH
- KMID: 1091208
- J Vet Sci.
- 2005 Sep;6(3):247-250.
Our recent study has provided that the in vitro SEC-induced proliferation of bovine T cells is preceded by a period of a non-proliferative immunoregulation of T cells that may be... -
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- BCG-Induced Dendritic Cell Responses and Suppression of Interleukin-5 Production from T Cells in Atopic Asthmatics
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Choi IS, Lin XH, Koh YA, Cui Y
- KMID: 1785821
- J Korean Med Sci.
- 2008 Aug;23(4):628-634.
- doi: 10.3346/jkms.2008.23.4.628
Bacille Calmette-Guerin (BCG) induces potent Th1 responses with the help of interleukin (IL)-10 and IL-12 released from dendritic cells (DCs), and suppresses Th2- associated allergic reactions. However, there are still... -
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- Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek's disease virus exposure
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Kim Y, Brown TP, Pantin-Jackwood MJ
- KMID: 1089605
- J Vet Sci.
- 2003 Dec;4(3):245-255.
In this study, we investigated the effects of T-cell suppression on the pathogenesis of subgroup J avian leukosis virus (ALV-J). Chickens were treated with cyclosporin A (CSP) 50 mg/Kg body... -
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- CD8+ T-cell Activation in Mice Injected with a Plasmid DNA Vaccine Encoding AMA-1 of the Reemerging Korean Plasmodium vivax
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Kim HJ, Jung BK, Lee JJ, Pyo KH, Kim TY, Choi BI, Kim TW, Hisaeda H, Himeno K, Shin EH, Chai JY
- KMID: 1715639
- Korean J Parasitol.
- 2011 Mar;49(1):85-90.
- doi: 10.3347/kjp.2011.49.1.85
Relatively little has been studied on the AMA-1 vaccine against Plasmodium vivax and on the plasmid DNA vaccine encoding P. vivax AMA-1 (PvAMA-1). In the present study, a plasmid DNA... -
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- Subdominant H60 antigen-specific CD8 T-cell response precedes dominant H4 antigen-specific response during the initial phase of allogenic skin graft rejection
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Yoo KI, Jeon JY, Ryu SJ, Nam G, Youn H, Choi EY
- KMID: 2155405
- Exp Mol Med.
- 2015 Feb;47(2):e140.
- doi: 10.1038/emm.2014.107
In allogeneic transplantation, including the B6 anti-BALB.B settings, H60 and H4 are two representative dominant minor histocompatibility antigens that induce strong CD8 T-cell responses. With different distribution patterns, H60 expression... -
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